Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Zzz3 (from a repository: Thu Apr 19 10:21:45 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins2 (14.29 %)
The number (and %) of the tumor suppressors1 (7.14 %)
Total number of binary PPIs (saturation %)31 (34.07 %)
The number (and %) of affected PPIs13 (41.94 %)
PPI diameter2
PPI radius1
The average degree of PPI3.571
Assortativity coefficient-0.3959
The network average Clustering coefficient0.592
The number (and %) of a zero Clustering coefficients4 (28.57 %)
The number (and %) of a zero Betweenness Centrality9 (64.29 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Zzz3
user protein130.154125.500Myb_DNA-binding (PF00249): Myb-like DNA-binding domain
ZZ (PF00569): Zinc finger, ZZ type
Brca1
oncogene, tumor suppressor31.0000zf-C3HC4 (PF00097): Zinc finger, C3HC4 type (RING finger)
S36_mt (PF10937): Ribosomal protein S36, mitochondrial
BRCT_assoc (PF12820): Serine-rich domain associated with BRCT
BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
RTT107_BRCT_5 (PF16770): Regulator of Ty1 transposition protein 107 BRCT domain
Eps8
oncogene200PTB (PF08416): Phosphotyrosine-binding domain
Mito_fiss_reg (PF05308): Mitochondrial fission regulator
Med2 (PF11214): Mediator complex subunit 2
SH3_3 (PF08239): Bacterial SH3 domain
SH3_1 (PF00018): SH3 domain
DEC-1_N (PF04625): DEC-1 protein, N-terminal region
Hecw2
interactor40.6671.000HECW_N (PF16562): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
C2 (PF00168): C2 domain
Cep57_CLD (PF14073): Centrosome localisation domain of Cep57
WW (PF00397): WW domain
RFXA_RFXANK_bdg (PF15289): Regulatory factor X-associated C-terminal binding domain
HECT (PF00632): HECT-domain (ubiquitin-transferase)
Ikzf5
interactor51.0000zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-C2H2_7 (PF15269): Zinc-finger
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Kat2a
interactor70.6674.500NICE-1 (PF15845): Cysteine-rich C-terminal 1 family
PCAF_N (PF06466): PCAF (P300/CBP-associated factor) N-terminal domain
Acetyltransf_1 (PF00583): Acetyltransferase (GNAT) family
Bromodomain (PF00439): Bromodomain
Maml3
interactor100MamL-1 (PF09596): MamL-1 domain
Rtf2 (PF04641): Rtf2 RING-finger
SRRM_C (PF15230): Serine/arginine repetitive matrix protein C-terminus
Drf_GBD (PF06371): Diaphanous GTPase-binding Domain
TERB2 (PF15101): Telomere-associated protein TERB2
PNISR (PF15996): Arginine/serine-rich protein PNISR
AAA_23 (PF13476): AAA domain
SurA_N_2 (PF13623): SurA N-terminal domain
TFIIA (PF03153): Transcription factor IIA, alpha/beta subunit
Rfpl4b
interactor100zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
PRY (PF13765): SPRY-associated domain
SPRY (PF00622): SPRY domain
zf-RING_UBOX (PF13445): RING-type zinc-finger
Tada2a
interactor50.9000.500Myb_DNA-binding (PF00249): Myb-like DNA-binding domain
SWIRM (PF04433): SWIRM domain
Tada3
interactor50.9000.500Ada3 (PF10198): Histone acetyltransferases subunit 3
GvpL_GvpF (PF06386): Gas vesicle synthesis protein GvpL/GvpF
Tfap4
oncogene21.0000HLH (PF00010): Helix-loop-helix DNA-binding domain
DivIC (PF04977): Septum formation initiator
DUF2407 (PF10302): DUF2407 ubiquitin-like domain
DUF972 (PF06156): Protein of unknown function (DUF972)
Wdr5
interactor41.0000WD40 (PF00400): WD domain, G-beta repeat
Zbtb9
interactor21.0000BTB (PF00651): BTB/POZ domain
Myc_N (PF01056): Myc amino-terminal region
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
zf-C2H2 (PF00096): Zinc finger, C2H2 type
Znf496
interactor200Rpr2 (PF04032): RNAse P Rpr2/Rpp21/SNM1 subunit domain
SCAN (PF02023): SCAN domain
KRAB (PF01352): KRAB box
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_2 (PF13465): Zinc-finger double domain

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