Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Zyg11b (from a repository: Thu Apr 19 16:01:11 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins3 (30.00 %)
The number (and %) of the tumor suppressors1 (10.00 %)
Total number of binary PPIs (saturation %)23 (51.11 %)
The number (and %) of affected PPIs9 (39.13 %)
PPI diameter2
PPI radius1
The average degree of PPI4.000
Assortativity coefficient-0.2169
The network average Clustering coefficient0.724
The number (and %) of a zero Clustering coefficients1 (10.00 %)
The number (and %) of a zero Betweenness Centrality6 (60.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Zyg11b
user protein90.30640.000DUF3361 (PF11841): Domain of unknown function (DUF3361)
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
BAF250_C (PF12031): SWI/SNF-like complex subunit BAF250/Osa
Ap3s1
interactor21.0000Clat_adaptor_s (PF01217): Clathrin adaptor complex small chain
Atp13a1
interactor21.0000E1-E2_ATPase (PF00122): E1-E2 ATPase
Hydrolase (PF00702): haloacid dehalogenase-like hydrolase
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
zf-DHHC (PF01529): DHHC palmitoyltransferase
Crocc
interactor100SOGA (PF11365): Protein SOGA
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
JIP_LZII (PF16471): JNK-interacting protein leucine zipper II
Rho_Binding (PF08912): Rho Binding
KfrA_N (PF11740): Plasmid replication region DNA-binding N-term
APG6 (PF04111): Autophagy protein Apg6
DUF4472 (PF14739): Domain of unknown function (DUF4472)
DUF724 (PF05266): Protein of unknown function (DUF724)
CENP-F_leu_zip (PF10473): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Reo_sigmaC (PF04582): Reovirus sigma C capsid protein
HIP1_clath_bdg (PF16515): Clathrin-binding domain of Huntingtin-interacting protein 1
DUF1664 (PF07889): Protein of unknown function (DUF1664)
COG2 (PF06148): COG (conserved oligomeric Golgi) complex component, COG2
TPR_MLP1_2 (PF07926): TPR/MLP1/MLP2-like protein
Spc7 (PF08317): Spc7 kinetochore protein
DUF972 (PF06156): Protein of unknown function (DUF972)
DUF4140 (PF13600): N-terminal domain of unknown function (DUF4140)
Imm1 (PF14430): Immunity protein Imm1
DUF3450 (PF11932): Protein of unknown function (DUF3450)
BLOC1_2 (PF10046): Biogenesis of lysosome-related organelles complex-1 subunit 2
ERM (PF00769): Ezrin/radixin/moesin family
Cul2
tumor suppressor60.6006.000Cullin (PF00888): Cullin family
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Elavl1
oncogene50.6672.000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Elob
interactor41.0000ubiquitin (PF00240): Ubiquitin family
Eloc
oncogene41.0000Skp1_POZ (PF03931): Skp1 family, tetramerisation domain
Nedd8
interactor51.0000ubiquitin (PF00240): Ubiquitin family
Ntrk1
oncogene50.6672.000LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase

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