Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Zxdc (from a repository: Thu Apr 12 12:15:48 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)13
The number (and %) of the onco-proteins3 (23.08 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)25 (32.05 %)
The number (and %) of affected PPIs12 (48.00 %)
PPI diameter2
PPI radius1
The average degree of PPI2.923
Assortativity coefficient-0.6832
The network average Clustering coefficient0.543
The number (and %) of a zero Clustering coefficients4 (30.77 %)
The number (and %) of a zero Betweenness Centrality10 (76.92 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Zxdc
user protein120.106102.000zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-C2H2_aberr (PF17017): Aberrant zinc-finger
zf-C2H2_8 (PF15909): C2H2-type zinc ribbon
zf-C2H2_4 (PF13894): C2H2-type zinc finger
App
interactor80.28615.000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Atxn1
interactor200ATXN-1_C (PF12547): Capicua transcriptional repressor modulator
AXH (PF08517): Ataxin-1 and HBP1 module (AXH)
Jtb
interactor21.0000JTB (PF05439): Jumping translocation breakpoint protein (JTB)
Nr1h2
oncogene100zf-C4 (PF00105): Zinc finger, C4 type (two domains)
DUF1180 (PF06679): Protein of unknown function (DUF1180)
Hormone_recep (PF00104): Ligand-binding domain of nuclear hormone receptor
Nr1h3
interactor21.0000zf-C4 (PF00105): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104): Ligand-binding domain of nuclear hormone receptor
Nxf1
interactor31.0000Tap-RNA_bind (PF09162): Tap, RNA-binding
LRR_8 (PF13855): Leucine rich repeat
NTF2 (PF02136): Nuclear transport factor 2 (NTF2) domain
TAP_C (PF03943): TAP C-terminal domain
Pogz
interactor30.6671.000zf-UDP (PF14569): Zinc-binding RING-finger
zf-C2H2_6 (PF13912): C2H2-type zinc finger
Rubredoxin (PF00301): Rubredoxin
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-RRN7 (PF11781): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-RING_5 (PF14634): zinc-RING finger domain
HTH_28 (PF13518): Helix-turn-helix domain
HTH_Tnp_Tc5 (PF03221): Tc5 transposase DNA-binding domain
DDE_1 (PF03184): DDE superfamily endonuclease
Rora
interactor100zf-C4 (PF00105): Zinc finger, C4 type (two domains)
zf-C3HC (PF07967): C3HC zinc finger-like
Hormone_recep (PF00104): Ligand-binding domain of nuclear hormone receptor
Sh3gl2
oncogene31.0000BAR (PF03114): BAR domain
SH3_1 (PF00018): SH3 domain
Smn1
interactor200SMN (PF06003): Survival motor neuron protein (SMN)
Tk1
oncogene31.0000TK (PF00265): Thymidine kinase
Wdr5
interactor21.0000WD40 (PF00400): WD domain, G-beta repeat

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