Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Zscan18 (from a repository: Fri May 11 03:21:08 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors1 (12.50 %)
Total number of binary PPIs (saturation %)12 (42.86 %)
The number (and %) of affected PPIs7 (58.33 %)
PPI diameter2
PPI radius1
The average degree of PPI2.250
Assortativity coefficient-0.5250
The network average Clustering coefficient0.345
The number (and %) of a zero Clustering coefficients4 (50.00 %)
The number (and %) of a zero Betweenness Centrality6 (75.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure		 Type Number
of PPI (degree)		 Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam ID): description
Zscan18

Domain structure obtained by HMM

Protein ID: XP_008820989.2 - zinc finger and SCAN domain-containing protein 18
KEEG Ortholog ID: K09230
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
MitofilinPF097316230.0140.200271159123Mitochondrial inner membrane protein
AmelogeninPF029481730.0251.400181244166256Amelogenin
Herpes_BTRF1PF046822590.0240.100395442388450Herpesvirus BTRF1 protein conserved region
Pro_CAPF004841560.0231.200494529462542Carbonic anhydrase
SCANPF02023901.8e-38116.600580666579668SCAN domain
Neur_chan_membPF029322380.0240.800815869727915Neurotransmitter-gated ion-channel transmembrane region
PTPRCAPPF157131480.0181.500849902826917Protein tyrosine phosphatase receptor type C-associated
zf-C2H2PF00096230.00003910.500956978956978Zinc finger, C2H2 type
user protein70.09537.000Mitofilin (PF09731): Mitochondrial inner membrane protein
Amelogenin (PF02948): Amelogenin
Herpes_BTRF1 (PF04682): Herpesvirus BTRF1 protein conserved region
Pro_CA (PF00484): Carbonic anhydrase
SCAN (PF02023): SCAN domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
PTPRCAP (PF15713): Protein tyrosine phosphatase receptor type C-associated
zf-C2H2 (PF00096): Zinc finger, C2H2 type
App

Domain structure obtained by HMM

Protein ID: XP_017657176.1 - amyloid beta A4 protein
KEEG Ortholog ID: K04520
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
APP_NPF021771008.1e-49150.5003113131131Amyloid A4 N-terminal heparin-binding
APP_Cu_bdPF12924571.8e-2988.600132188132188Copper-binding of amyloid precursor, CuBD
SDA1PF052853470.000005912.000193270155307SDA1
YtxHPF12732750.00483.800251291245298YtxH-like protein
Kunitz_BPTIPF00014531.4e-2369.200291342291343Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2PF129251901e-78249.500365547365547E2 domain of amyloid precursor protein
YtxHPF12732750.0291.300520565516576YtxH-like protein
Beta-APPPF03494393.3e-2883.600676712674712Beta-amyloid peptide (beta-APP)
APP_amyloidPF10515523.7e-2987.400715765715765beta-amyloid precursor protein C-terminus
interactor31.0000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Epm2aip1

Domain structure obtained by HMM

Protein ID: XP_008828632.1 - EPM2A-interacting protein 1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
KxDLPF10241860.00002710.700465487459491Uncharacterized conserved protein
interactor200KxDL (PF10241): Uncharacterized conserved protein
Hoxd4

Domain structure obtained by HMM

Protein ID: XP_008853536.1 - homeobox protein Hox-D4
KEEG Ortholog ID: K09304
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
HomeoboxPF00046574.9e-2676.700153209153209Homeobox domain
SR-25PF105002270.00000114.600203233154249Nuclear RNA-splicing-associated protein
DGF-1_CPF11040870.000005712.600217250205253Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
interactor100Homeobox (PF00046): Homeobox domain
SR-25 (PF10500): Nuclear RNA-splicing-associated protein
DGF-1_C (PF11040): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
Lig4

Domain structure obtained by HMM

Protein ID: XP_008853418.1 - DNA ligase 4
KEEG Ortholog ID: K10777
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DNA_ligase_A_NPF046751739.6e-46142.4001520815208DNA ligase N terminus
APG17PF041083940.000005111.800200266146292Autophagy protein Apg17
DNA_ligase_A_MPF010682043.3e-58182.800248451248451ATP dependent DNA ligase domain
DNA_ligase_A_CPF04679991.3e-2163.400476588476588ATP dependent DNA ligase C terminal region
BRCT_2PF16589850.000000000001334.300657740655742BRCT domain, a BRCA1 C-terminus domain
DNA_ligase_IVPF11411344.6e-2161.000750782750783DNA ligase IV
BRCTPF00533790.000000001824.300845898811898BRCA1 C Terminus (BRCT) domain
RTT107_BRCT_5PF167701000.000098.600878911820911Regulator of Ty1 transposition protein 107 BRCT domain
interactor100DNA_ligase_A_N (PF04675): DNA ligase N terminus
APG17 (PF04108): Autophagy protein Apg17
DNA_ligase_A_M (PF01068): ATP dependent DNA ligase domain
DNA_ligase_A_C (PF04679): ATP dependent DNA ligase C terminal region
BRCT_2 (PF16589): BRCT domain, a BRCA1 C-terminus domain
DNA_ligase_IV (PF11411): DNA ligase IV
BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
RTT107_BRCT_5 (PF16770): Regulator of Ty1 transposition protein 107 BRCT domain
Safb2

Domain structure obtained by HMM

Protein ID: XP_008835173.1 - scaffold attachment factor B2 isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
SAPPF02037350.00000000000001140.20020532054SAP domain
Asp-B-Hydro_NPF052792430.0151.5005112323139Aspartyl beta-hydroxylase N-terminal region
Asp-B-Hydro_NPF052792430.000675.900186301161353Aspartyl beta-hydroxylase N-terminal region
RRM_1PF00076704.7e-1748.000426494426496RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
tumor suppressor100SAP (PF02037): SAP domain
Asp-B-Hydro_N (PF05279): Aspartyl beta-hydroxylase N-terminal region
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Zscan10

Domain structure obtained by HMM

Protein ID: XP_008844048.1 - zinc finger and SCAN domain-containing protein 10
KEEG Ortholog ID: K09230
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
SCANPF02023906.9e-3398.7004012540128SCAN domain
zf-C2H2PF00096230.000002414.300346369346369Zinc finger, C2H2 type
zf-C2H2_4PF13894240.00004710.600375397375398C2H2-type zinc finger
zf-H2C2_2PF13465260.00000001121.700390413390414Zinc-finger double domain
zf-C2H2PF00096230.0000001518.100403425403425Zinc finger, C2H2 type
zf-C2H2PF00096230.0000005916.200431453431453Zinc finger, C2H2 type
zinc_ribbon_9PF14369350.000148.400470484460486zinc-ribbon
zf-C2H2PF00096230.00000006519.200477497476497Zinc finger, C2H2 type
zf-H2C2_2PF13465260.000178.500489531489532Zinc-finger double domain
zf-C2H2PF00096230.0000000000728.600521543521543Zinc finger, C2H2 type
zf-H2C2_2PF13465260.000000002423.800535559535560Zinc-finger double domain
zf-H2C2_2PF13465260.00000000006928.600564587563588Zinc-finger double domain
zf-C2H2PF00096230.00000007919.000577599577599Zinc finger, C2H2 type
zf-C2H2_6PF13912270.00000006618.700605628604630C2H2-type zinc finger
zf-H2C2_2PF13465260.0000000005925.700619643619644Zinc-finger double domain
zf-H2C2_2PF13465260.0000000003126.600647672647672Zinc-finger double domain
zf-H2C2_2PF13465260.000000000001533.900675699675700Zinc-finger double domain
zf-C2H2PF00096230.0000000004526.000689711689711Zinc finger, C2H2 type
zf-H2C2_2PF13465260.000000007322.200703732703733Zinc-finger double domain
zf-C2H2PF00096230.000000006222.400723744722744Zinc finger, C2H2 type
zf-C2H2PF00096230.000000001724.200750772750772Zinc finger, C2H2 type
zf-H2C2_2PF13465260.0241.700764777764778Zinc-finger double domain
interactor40.6671.000SCAN (PF02023): SCAN domain
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_2 (PF13465): Zinc-finger double domain
zinc_ribbon_9 (PF14369): zinc-ribbon
zf-C2H2_6 (PF13912): C2H2-type zinc finger
Zscan20

Domain structure obtained by HMM

Protein ID: XP_008827450.1 - zinc finger and SCAN domain-containing protein 20 isoform X1
KEEG Ortholog ID: K09230
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
SCANPF02023908.8e-43130.4004813448137SCAN domain
Myb_DNA-bind_4PF13837902.3e-2059.100323406321406Myb/SANT-like DNA-binding domain
Fer4_8PF13183650.050.4003974553904574Fe-4S dicluster domain
Myb_DNA-bind_4PF13837904.2e-2058.300483566481566Myb/SANT-like DNA-binding domain
PHDPF00628520.0470.000663676656677PHD-finger
zf-C2H2PF00096230.0000008615.700706725706728Zinc finger, C2H2 type
zf-H2C2_2PF13465260.000000003223.400721744720745Zinc-finger double domain
zf-C2H2PF00096230.00000001821.000734756734756Zinc finger, C2H2 type
zf-H2C2_2PF13465260.00000000124.900751772748773Zinc-finger double domain
zf-H2C2_2PF13465260.00000002920.300777800776801Zinc-finger double domain
zf-C2H2PF00096230.000000002223.900790812790812Zinc finger, C2H2 type
zf-H2C2_2PF13465260.00284.600804820804822Zinc-finger double domain
zf-H2C2_2PF13465260.00001112.200866880861881Zinc-finger double domain
zf-C2H2PF00096230.0000000002626.800870892870892Zinc finger, C2H2 type
zf-H2C2_2PF13465260.000000000003132.900885908884909Zinc-finger double domain
zf-H2C2_2PF13465260.0000000001827.300913936912937Zinc-finger double domain
zf-C2H2PF00096230.000000003823.100926948926948Zinc finger, C2H2 type
zf-H2C2_2PF13465260.0000000002127.100943963940964Zinc-finger double domain
zf-H2C2_2PF13465260.00000000004529.200968992968993Zinc-finger double domain
zf-C2H2PF00096230.0000000008825.10098210049821004Zinc finger, C2H2 type
zf-H2C2_2PF13465260.00000000001830.400100010219961021Zinc-finger double domain
zf-C2H2PF00096230.000000005822.5001010103210101032Zinc finger, C2H2 type
interactor21.0000SCAN (PF02023): SCAN domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
Fer4_8 (PF13183): 4Fe-4S dicluster domain
PHD (PF00628): PHD-finger
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain

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