Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Znrf3 (from a repository: Wed Apr 11 04:13:28 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins5 (50.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)17 (37.78 %)
The number (and %) of affected PPIs9 (52.94 %)
PPI diameter2
PPI radius1
The average degree of PPI2.600
Assortativity coefficient-0.5309
The network average Clustering coefficient0.561
The number (and %) of a zero Clustering coefficients3 (30.00 %)
The number (and %) of a zero Betweenness Centrality8 (80.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Znrf3
user protein90.11161.000PA (PF02225): PA domain
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
zf-RING_2 (PF13639): Ring finger domain
zf-C3H2C3 (PF17122): Zinc-finger
Dvl2
interactor200DIX (PF00778): DIX domain
Mito_fiss_reg (PF05308): Mitochondrial fission regulator
Dishevelled (PF02377): Dishevelled specific domain
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
DEP (PF00610): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dsh_C (PF12316): Segment polarity protein dishevelled (Dsh) C terminal
Fzd4
interactor100Fz (PF01392): Fz domain
Frizzled (PF01534): Frizzled/Smoothened family membrane region
Gfi1b
oncogene100UBZ_FAAP20 (PF15750): Ubiquitin-binding zinc-finger
SPR1 (PF15356): Psoriasis susceptibility locus 2
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Hspb1
heat shock, oncogene31.0000HSP20 (PF00011): Hsp20/alpha crystallin family
Lgr4
interactor50.5003.000LRRNT (PF01462): Leucine rich repeat N-terminal domain
LRR_8 (PF13855): Leucine rich repeat
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
7tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Rspo1
oncogene21.0000Furin-like_2 (PF15913): Furin-like repeat, cysteine-rich
TSP_1 (PF00090): Thrombospondin type 1 domain
Rspo2
oncogene21.0000Furin-like_2 (PF15913): Furin-like repeat, cysteine-rich
VSP (PF03302): Giardia variant-specific surface protein
CDT1 (PF08839): DNA replication factor CDT1 like
Rspo3
oncogene21.0000Furin-like_2 (PF15913): Furin-like repeat, cysteine-rich
TSP_1 (PF00090): Thrombospondin type 1 domain
RR_TM4-6 (PF06459): Ryanodine Receptor TM 4-6
Ube2n
interactor31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme

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