Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Znrf1 (from a repository: Fri Apr 20 03:29:38 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)22
The number (and %) of the onco-proteins4 (18.18 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)42 (18.18 %)
The number (and %) of affected PPIs22 (52.38 %)
PPI diameter2
PPI radius1
The average degree of PPI2.818
Assortativity coefficient-0.6937
The network average Clustering coefficient0.515
The number (and %) of a zero Clustering coefficients9 (40.91 %)
The number (and %) of a zero Betweenness Centrality20 (90.91 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Znrf1
user protein220.048380.000zf-Di19 (PF05605): Drought induced 19 protein (Di19), zinc-binding
RNF220 (PF15926): E3 ubiquitin-protein ligase RNF220
zf-RING_2 (PF13639): Ring finger domain
Aars2
oncogene21.0000tRNA-synt_2c (PF01411): tRNA synthetases class II (A)
tRNA_SAD (PF07973): Threonyl and Alanyl tRNA synthetase second additional domain
Seryl_tRNA_N (PF02403): Seryl-tRNA synthetase N-terminal domain
Atp1a1
interactor21.0000Cation_ATPase_N (PF00690): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122): E1-E2 ATPase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
Cation_ATPase_C (PF00689): Cation transporting ATPase, C-terminus
Bhmt
interactor200S-methyl_trans (PF02574): Homocysteine S-methyltransferase
HrcA (PF01628): HrcA protein C terminal domain
Cdc34
oncogene31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Fbxw5
interactor100F-box-like (PF12937): F-box-like
WD40 (PF00400): WD domain, G-beta repeat
Glul
interactor31.0000Gln-synt_N (PF03951): Glutamine synthetase, beta-Grasp domain
Gln-synt_C (PF00120): Glutamine synthetase, catalytic domain
Nceh1
interactor100Abhydrolase_3 (PF07859): alpha/beta hydrolase fold
Nmt1
oncogene100NST1 (PF13945): Salt tolerance down-regulator
SR-25 (PF10500): Nuclear RNA-splicing-associated protein
NMT (PF01233): Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
NMT_C (PF02799): Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
Nmt2
interactor100Nop53 (PF07767): Nop53 (60S ribosomal biogenesis)
NMT (PF01233): Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
NMT_C (PF02799): Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
Tsen2
interactor21.0000Ovate (PF04844): Transcriptional repressor, ovate
tRNA_int_endo_N (PF02778): tRNA intron endonuclease, N-terminal domain
tRNA_int_endo (PF01974): tRNA intron endonuclease, catalytic C-terminal domain
Tsen54
interactor21.0000tRNA_int_end_N2 (PF12928): tRNA-splicing endonuclease subunit sen54 N-term
tRNA_int_endo_N (PF02778): tRNA intron endonuclease, N-terminal domain
Ubc
interactor90.28620.000ubiquitin (PF00240): Ubiquitin family
Ube2d1
interactor41.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2d2
oncogene41.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2d4
interactor200UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2e1
interactor200SR-25 (PF10500): Nuclear RNA-splicing-associated protein
UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2e3
interactor21.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2n
interactor31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2v1
interactor100UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2w
interactor200UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ywhaq
interactor21.000014-3-3 (PF00244): 14-3-3 protein

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