Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Znrd1 (from a repository: Fri Apr 13 14:08:43 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins2 (14.29 %)
The number (and %) of the tumor suppressors1 (7.14 %)
Total number of binary PPIs (saturation %)24 (26.37 %)
The number (and %) of affected PPIs13 (54.17 %)
PPI diameter2
PPI radius1
The average degree of PPI2.429
Assortativity coefficient-0.5230
The network average Clustering coefficient0.361
The number (and %) of a zero Clustering coefficients8 (57.14 %)
The number (and %) of a zero Betweenness Centrality13 (92.86 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Znrd1
user protein130.051148.000DZR (PF12773): Double zinc ribbon
zf-ISL3 (PF14690): zinc-finger of transposase IS204/IS1001/IS1096/IS1165
TFIIS_C (PF01096): Transcription factor S-II (TFIIS)
Atxn2
interactor100SM-ATX (PF14438): Ataxin 2 SM domain
LsmAD (PF06741): LsmAD domain
PAM2 (PF07145): Ataxin-2 C-terminal region
DUF3446 (PF11928): Domain of unknown function (DUF3446)
Dusp1
tumor suppressor200Rhodanese (PF00581): Rhodanese-like domain
DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Gpr20
interactor1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Ivns1abp
interactor200BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Kelch_1 (PF01344): Kelch motif
Mapk8ip2
interactor200PBP_sp32 (PF07222): Proacrosin binding protein sp32
RXT2_N (PF08595): RXT2-like, N-terminal
TonB_N (PF16031): TonB N-terminal region
CENP-B_dimeris (PF09026): Centromere protein B dimerisation domain
S-antigen (PF05756): S-antigen protein
SH3_9 (PF14604): Variant SH3 domain
PID (PF00640): Phosphotyrosine interaction domain (PTB/PID)
Nono
oncogene31.0000SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
NOPS (PF08075): NOPS (NUC059) domain
PAS_7 (PF12860): PAS fold
GvpL_GvpF (PF06386): Gas vesicle synthesis protein GvpL/GvpF
Pms2
oncogene100HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
DNA_mis_repair (PF01119): DNA mismatch repair protein, C-terminal domain
MutL_C (PF08676): MutL C terminal dimerisation domain
Polr1a
interactor31.0000RNA_pol_Rpb1_1 (PF04997): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998): RNA polymerase Rpb1, domain 5
Polr2e
interactor41.0000RNA_pol_Rpb5_N (PF03871): RNA polymerase Rpb5, N-terminal domain
RNA_pol_Rpb5_C (PF01191): RNA polymerase Rpb5, C-terminal domain
Polr2f
interactor31.0000BDHCT_assoc (PF16204): BDHCT-box associated domain on Bloom syndrome protein
RNA_pol_Rpb6 (PF01192): RNA polymerase Rpb6
Sacs
interactor100DUF4368 (PF14287): Domain of unknown function (DUF4368)
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
DnaJ (PF00226): DnaJ domain
HEPN (PF05168): HEPN domain
Tns2
interactor200C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
PTEN_C2 (PF10409): C2 domain of PTEN tumour-suppressor protein
cEGF (PF12662): Complement Clr-like EGF-like
SH2 (PF00017): SH2 domain
PTB (PF08416): Phosphotyrosine-binding domain
Ube2i
interactor31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme

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