Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Znhit1 (from a repository: Fri Apr 20 11:11:26 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)17
The number (and %) of the onco-proteins3 (17.65 %)
The number (and %) of the tumor suppressors1 (5.88 %)
Total number of binary PPIs (saturation %)43 (31.62 %)
The number (and %) of affected PPIs16 (37.21 %)
PPI diameter2
PPI radius1
The average degree of PPI4.353
Assortativity coefficient-0.4064
The network average Clustering coefficient0.599
The number (and %) of a zero Clustering coefficients4 (23.53 %)
The number (and %) of a zero Betweenness Centrality9 (52.94 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Znhit1
user protein160.175180.067zf-HIT (PF04438): HIT zinc finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Actr6
interactor70.7623.067Actin (PF00022): Actin
Dapp1
interactor100SH2 (PF00017): SH2 domain
PH (PF00169): PH domain
Grb7
interactor100RA (PF00788): Ras association (RalGDS/AF-6) domain
PH (PF00169): PH domain
BPS (PF08947): BPS (Between PH and SH2)
SH2 (PF00017): SH2 domain
Hinfp
interactor21.0000FOXP-CC (PF16159): FOXP coiled-coil domain
zf-met (PF12874): Zinc-finger of C2H2 type
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-Dof (PF02701): Dof domain, zinc finger
SLIDE (PF09111): SLIDE
LOC103733695
interactor70.9330.400Histone (PF00125): Core histone H2A/H2B/H3/H4
EOS1 (PF12326): N-glycosylation protein
LOC103746136
interactor80.7145.400Histone (PF00125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211): C-terminus of histone H2A
DUF1764 (PF08576): Eukaryotic protein of unknown function (DUF1764)
Macro (PF01661): Macro domain
Lca5
interactor100Lebercilin (PF15619): Ciliary protein causing Leber congenital amaurosis disease
IFP_35_N (PF07334): Interferon-induced 35 kDa protein (IFP 35) N-terminus
GreA_GreB_N (PF03449): Transcription elongation factor, N-terminal
DUF5082 (PF16888): Domain of unknown function (DUF5082)
GAS (PF13851): Growth-arrest specific micro-tubule binding
Mapk14
oncogene40.6671.000Pkinase (PF00069): Protein kinase domain
Nfatc2ip
interactor21.0000Rad60-SLD (PF11976): Ubiquitin-2 like Rad60 SUMO-like
P4ha3
interactor40.6672.000P4Ha_N (PF08336): Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
SPO22 (PF08631): Meiosis protein SPO22/ZIP4 like
2OG-FeII_Oxy_3 (PF13640): 2OG-Fe(II) oxygenase superfamily
Ruvbl1
oncogene51.0000TIP49 (PF06068): TIP49 C-terminus
Ruvbl2
oncogene61.0000TIP49 (PF06068): TIP49 C-terminus
Sh2d1a
interactor21.0000SH2 (PF00017): SH2 domain
Tnip1
interactor200Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
Pinin_SDK_memA (PF04696): pinin/SDK/memA/ protein conserved region
DUF4337 (PF14235): Domain of unknown function (DUF4337)
Filament (PF00038): Intermediate filament protein
CC2-LZ (PF16516): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Mnd1 (PF03962): Mnd1 family
Tp53
tumor suppressor50.5003.000P53_TAD (PF08563): P53 transactivation motif
P53 (PF00870): P53 DNA-binding domain
P53_tetramer (PF07710): P53 tetramerisation motif
Yeats4
interactor70.7623.067YEATS (PF03366): YEATS family
SOGA (PF11365): Protein SOGA

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