Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Znf581 (from a repository: Fri May 11 01:58:22 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)36
The number (and %) of the onco-proteins8 (22.22 %)
The number (and %) of the tumor suppressors6 (16.67 %)
Total number of binary PPIs (saturation %)77 (12.22 %)
The number (and %) of affected PPIs35 (45.45 %)
PPI diameter2
PPI radius1
The average degree of PPI3.056
Assortativity coefficient-0.5502
The network average Clustering coefficient0.389
The number (and %) of a zero Clustering coefficients16 (44.44 %)
The number (and %) of a zero Betweenness Centrality24 (66.67 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure		 Type Number
of PPI (degree)		 Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam ID): description
Znf581

Domain structure obtained by HMM

Protein ID: XP_017657046.1 - LOW QUALITY PROTEIN: zinc finger protein 581
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
PBP_NPF170931380.000004913.10029762594Penicillin-binding protein N-terminus
zf-C2H2_4PF13894240.00000006519.5009011190113C2H2-type zinc finger
zf-H2C2_2PF13465260.000000003523.200105128104128Zinc-finger double domain
zf-C2H2PF00096230.00001411.800118133118135Zinc finger, C2H2 type
zf-C2H2_4PF13894240.000527.400150170148171C2H2-type zinc finger
zf-H2C2_2PF13465260.000006712.900163180162184Zinc-finger double domain
user protein350.0341114.000PBP_N (PF17093): Penicillin-binding protein N-terminus
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-C2H2 (PF00096): Zinc finger, C2H2 type
Adnp

Domain structure obtained by HMM

Protein ID: XP_008833378.1 - activity-dependent neuroprotector homeobox protein isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
zf-C2H2_4PF13894240.00634.00074977497C2H2-type zinc finger
zf-H2C2_2PF13465260.000138.8008811488118Zinc-finger double domain
zf-Di19PF05605540.00000413.400108133106136Drought induced 19 protein (Di19), zinc-binding
Rpr2PF04032910.0241.300144170120171RNAse P Rpr2/Rpp21/SNM1 subunit domain
zf-C2H2_4PF13894240.00823.600165188165188C2H2-type zinc finger
zf-C2H2_2PF127561010.0570.100220249167255C2H2 type zinc-finger (2 copies)
zf-Di19PF05605540.00004610.000438469437470Drought induced 19 protein (Di19), zinc-binding
zf-C2H2_4PF13894240.0000005716.600513535512535C2H2-type zinc finger
Rpr2PF04032910.000168.300606668589669RNAse P Rpr2/Rpp21/SNM1 subunit domain
zf-BEDPF02892440.00184.700657688652689BED zinc finger
HomeoboxPF00046570.00000000004228.900770811766814Homeobox domain
interactor100zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-Di19 (PF05605): Drought induced 19 protein (Di19), zinc-binding
Rpr2 (PF04032): RNAse P Rpr2/Rpp21/SNM1 subunit domain
zf-C2H2_2 (PF12756): C2H2 type zinc-finger (2 copies)
zf-BED (PF02892): BED zinc finger
Homeobox (PF00046): Homeobox domain
App

Domain structure obtained by HMM

Protein ID: XP_017657176.1 - amyloid beta A4 protein
KEEG Ortholog ID: K04520
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
APP_NPF021771008.1e-49150.5003113131131Amyloid A4 N-terminal heparin-binding
APP_Cu_bdPF12924571.8e-2988.600132188132188Copper-binding of amyloid precursor, CuBD
SDA1PF052853470.000005912.000193270155307SDA1
YtxHPF12732750.00483.800251291245298YtxH-like protein
Kunitz_BPTIPF00014531.4e-2369.200291342291343Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2PF129251901e-78249.500365547365547E2 domain of amyloid precursor protein
YtxHPF12732750.0291.300520565516576YtxH-like protein
Beta-APPPF03494393.3e-2883.600676712674712Beta-amyloid peptide (beta-APP)
APP_amyloidPF10515523.7e-2987.400715765715765beta-amyloid precursor protein C-terminus
interactor70.33310.000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Banp

Domain structure obtained by HMM

Protein ID: XP_017655486.1 - protein BANP isoform X9
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF1845PF089002150.0000005115.7005011239116Domain of unknown function (DUF1845)
BENPF10523770.000000000008431.500259326258327BEN domain
tumor suppressor40.6671.000DUF1845 (PF08900): Domain of unknown function (DUF1845)
BEN (PF10523): BEN domain
Calcoco2

Domain structure obtained by HMM

Protein ID: XP_008836515.1 - calcium-binding and coiled-coil domain-containing protein 2 isoform X1
KEEG Ortholog ID: K21348
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
CALCOCO1PF078886069.7e-3296.3002213921144Calcium binding and coiled-coil domain (CALCOCO1) like
bZIP_1PF00170640.0000007815.500140170137171bZIP transcription factor
DUF641PF048591270.000006412.800154227117229Plant protein of unknown function (DUF641)
YlqDPF110681310.00018.900192264188268YlqD protein
HALZPF02183430.000004313.200321347321349Homeobox associated leucine zipper
interactor40.6671.000CALCOCO1 (PF07888): Calcium binding and coiled-coil domain (CALCOCO1) like
bZIP_1 (PF00170): bZIP transcription factor
DUF641 (PF04859): Plant protein of unknown function (DUF641)
YlqD (PF11068): YlqD protein
HALZ (PF02183): Homeobox associated leucine zipper
Ccdc136

Domain structure obtained by HMM

Protein ID: XP_017656918.1 - coiled-coil domain-containing protein 136 isoform X4
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ribosomal_60sPF00428880.00453.9006579608660s Acidic ribosomal protein
Baculo_PEP_CPF045131400.000004513.000124229119235Baculovirus polyhedron envelope protein, PEP, C terminus
HIP1_clath_bdgPF16515990.000003413.900226302221304Clathrin-binding domain of Huntingtin-interacting protein 1
HAP1_NPF048493090.000003212.600274390272397HAP1 N-terminal conserved region
ERMPF007692430.000009511.700335503310507Ezrin/radixin/moesin family
FliD_NPF02465970.0025.200518561514602Flagellar hook-associated protein 2 N-terminus
Sec34PF041361490.0000001118.100575627568634Sec34-like family
MacoilinPF097266710.00000113.600655972639984Transmembrane protein
FlxAPF142821010.00001811.00095910369551038FlxA-like protein
DUF2924PF111491350.00165.0001029107610201089Protein of unknown function (DUF2924)
AIF_CPF147211310.00852.7001041110310231104Apoptosis-inducing factor, mitochondrion-associated, C-term
tumor suppressor100Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
Baculo_PEP_C (PF04513): Baculovirus polyhedron envelope protein, PEP, C terminus
HIP1_clath_bdg (PF16515): Clathrin-binding domain of Huntingtin-interacting protein 1
HAP1_N (PF04849): HAP1 N-terminal conserved region
ERM (PF00769): Ezrin/radixin/moesin family
FliD_N (PF02465): Flagellar hook-associated protein 2 N-terminus
Sec34 (PF04136): Sec34-like family
Macoilin (PF09726): Transmembrane protein
FlxA (PF14282): FlxA-like protein
DUF2924 (PF11149): Protein of unknown function (DUF2924)
AIF_C (PF14721): Apoptosis-inducing factor, mitochondrion-associated, C-term
Ccndbp1

Domain structure obtained by HMM

Protein ID: XP_008845063.1 - cyclin-D1-binding protein 1 isoform X1
KEEG Ortholog ID: K21626
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
GCIPPF133242611e-80257.2007333472335Grap2 and cyclin-D-interacting
tumor suppressor100GCIP (PF13324): Grap2 and cyclin-D-interacting
Chd4

Domain structure obtained by HMM

Protein ID: XP_008823635.1 - chromodomain-helicase-DNA-binding protein 4 isoform X7
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DTHCTPF080701040.0000939.40010314798155DTHCT (NUC029) region
FAM176PF148511440.000237.100118169102184FAM176 family
CHDNTPF08073541.2e-2988.300165217164217CHDNT (NUC034) domain
Ribosomal_60sPF00428880.021.80022323419624960s Acidic ribosomal protein
Coilin_NPF158621390.00124.800311357310366Coilin N-terminus
zf-RING_9PF139012060.000157.900325378304403Putative zinc-RING and/or ribbon
PHDPF00628520.00000000000001140.400359403359404PHD-finger
PHDPF00628520.00000000000001140.400438482438483PHD-finger
ChromoPF00385550.000000008921.500527558518564Chromo (CHRromatin Organisation MOdifier) domain
ChromoPF00385551.8e-1646.100611654609661Chromo (CHRromatin Organisation MOdifier) domain
SNF2_NPF001763503.7e-63199.40072810116861012SNF2 family N-terminal domain
Helicase_CPF002711111.4e-2679.3001038115110371151Helicase conserved C-terminal domain
DUF1087PF06465631.6e-3091.3001281133912791339Domain of Unknown Function (DUF1087)
DUF1086PF064611387.9e-65203.1001370150713671508Domain of Unknown Function (DUF1086)
CDC27PF095074270.00791.6001493168114811686DNA polymerase subunit Cdc27
CHDCT2PF080741723.8e-89283.5001713188417121884CHDCT2 (NUC038) domain
oncogene60.4006.000DTHCT (PF08070): DTHCT (NUC029) region
FAM176 (PF14851): FAM176 family
CHDNT (PF08073): CHDNT (NUC034) domain
Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
Coilin_N (PF15862): Coilin N-terminus
zf-RING_9 (PF13901): Putative zinc-RING and/or ribbon
PHD (PF00628): PHD-finger
Chromo (PF00385): Chromo (CHRromatin Organisation MOdifier) domain
SNF2_N (PF00176): SNF2 family N-terminal domain
Helicase_C (PF00271): Helicase conserved C-terminal domain
DUF1087 (PF06465): Domain of Unknown Function (DUF1087)
DUF1086 (PF06461): Domain of Unknown Function (DUF1086)
CDC27 (PF09507): DNA polymerase subunit Cdc27
CHDCT2 (PF08074): CHDCT2 (NUC038) domain
Dazap2

Domain structure obtained by HMM

Protein ID: XP_008838230.1 - DAZ-associated protein 2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DAZAP2PF110291292.1e-43134.60021081108DAZ associated protein 2 (DAZAP2)
interactor50.5003.000DAZAP2 (PF11029): DAZ associated protein 2 (DAZAP2)
Diras2

Domain structure obtained by HMM

Protein ID: XP_008845575.1 - GTP-binding protein Di-Ras2
KEEG Ortholog ID: K07841
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
RasPF000711623.1e-53165.900101679171Ras family
ArgKPF033082670.0000448.60012118987197ArgK protein
interactor100Ras (PF00071): Ras family
ArgK (PF03308): ArgK protein
Dmwd

Domain structure obtained by HMM

Protein ID: XP_008850318.1 - dystrophia myotonica WD repeat-containing protein
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ANAPC4_WD40PF12894920.00115.600137183127189Anaphase-promoting complex subunit 4 WD40 domain
WD40PF00400380.000003914.000226250215251WD domain, G-beta repeat
WD40PF00400380.00000002720.800268293260293WD domain, G-beta repeat
WD40PF00400380.0000410.800304332297335WD domain, G-beta repeat
interactor100ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
WD40 (PF00400): WD domain, G-beta repeat
Dock8

Domain structure obtained by HMM

Protein ID: XP_008849826.1 - dedicator of cytokinesis protein 8
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DOCK-C2PF144291910.0000000000928.100166167C2 domain in Dock180 and Zizimin proteins
DHR-2PF069205285.4e-121390.80078511097821109Dock homology region 2
DHR-2PF069205289.6e-2469.9001108118011071181Dock homology region 2
interactor200DOCK-C2 (PF14429): C2 domain in Dock180 and Zizimin proteins
DHR-2 (PF06920): Dock homology region 2
Erbin

Domain structure obtained by HMM

Protein ID: XP_008837037.1 - protein LAP2 isoform X1
KEEG Ortholog ID: K12796
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
LRR_8PF13855610.000000000002133.0004710446104Leucine rich repeat
LRR_8PF13855610.000001514.3009314692148Leucine rich repeat
LRR_8PF13855610.0000003716.200125173116173Leucine rich repeat
LRR_8PF13855610.000000001523.800139195138196Leucine rich repeat
LRR_8PF13855610.00000000003429.100162219161219Leucine rich repeat
LRR_8PF13855610.000000001423.900209265208265Leucine rich repeat
LRR_8PF13855610.00000000002429.600231288230288Leucine rich repeat
LRR_8PF13855610.000000001124.300254311253311Leucine rich repeat
LRR_4PF12799430.00002411.100301337300343Leucine Rich repeats (2 copies)
LRR_8PF13855610.00000000008427.800330380322380Leucine rich repeat
LRR_8PF13855610.00000000001430.400346402345402Leucine rich repeat
Neur_chan_membPF029322380.000128.300426517361529Neurotransmitter-gated ion-channel transmembrane region
PDZPF00595823.7e-1852.0001370144813631449PDZ domain (Also known as DHR or GLGF)
oncogene200LRR_8 (PF13855): Leucine rich repeat
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Fsd2

Domain structure obtained by HMM

Protein ID: XP_008831249.1 - fibronectin type III and SPRY domain-containing protein 2 isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF4994PF16385980.000576.10028572459Domain of unknown function
Fumerase_CPF056832090.0000111.100129190119207Fumarase C-terminus
DUF3552PF120722010.000004412.400172287160294Domain of unknown function (DUF3552)
fn3PF00041852.5e-1646.200343425336425Fibronectin type III domain
fn3PF00041850.00000004919.600451519435519Fibronectin type III domain
PRYPF13765490.0000000004625.300532579531580SPRY-associated domain
SPRYPF006221200.0000000000001537.200586702586705SPRY domain
interactor100DUF4994 (PF16385): Domain of unknown function
Fumerase_C (PF05683): Fumarase C-terminus
DUF3552 (PF12072): Domain of unknown function (DUF3552)
fn3 (PF00041): Fibronectin type III domain
PRY (PF13765): SPRY-associated domain
SPRY (PF00622): SPRY domain
Gopc

Domain structure obtained by HMM

Protein ID: XP_008834007.1 - Golgi-associated PDZ and coiled-coil motif-containing protein isoform X1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF3209PF114831240.0221.50035653073Protein of unknown function (DUF3209)
NPV_P10PF05531750.00001911.4006910461144Nucleopolyhedrovirus P10 protein
DUF3209PF114831240.000188.2008411374139Protein of unknown function (DUF3209)
DivICPF04977800.000167.8009312067123Septum formation initiator
bZIP_2PF07716540.0000007615.500167200166200Basic region leucine zipper
CENP-HPF058371120.0440.500179219172254Centromere protein H (CENP-H)
PDZPF00595825.6e-2161.100291368289369PDZ domain (Also known as DHR or GLGF)
DUF903PF06004490.000001214.600372399370401Bacterial protein of unknown function (DUF903)
oncogene200DUF3209 (PF11483): Protein of unknown function (DUF3209)
NPV_P10 (PF05531): Nucleopolyhedrovirus P10 protein
DivIC (PF04977): Septum formation initiator
bZIP_2 (PF07716): Basic region leucine zipper
CENP-H (PF05837): Centromere protein H (CENP-H)
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
DUF903 (PF06004): Bacterial protein of unknown function (DUF903)
Hikeshi

Domain structure obtained by HMM

Protein ID: XP_008842361.1 - protein Hikeshi isoform X1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF775PF056032003.8e-56175.900111976197Protein of unknown function (DUF775)
interactor21.0000DUF775 (PF05603): Protein of unknown function (DUF775)
Hmbox1

Domain structure obtained by HMM

Protein ID: XP_008826337.1 - homeobox-containing protein 1 isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF494PF043611530.000001814.1001360775Protein of unknown function (DUF494)
HNF-1_NPF048141941.4e-66211.0002522625227Hepatocyte nuclear factor 1 (HNF-1), N terminus
HomeoboxPF00046570.000000000000009640.500269339268339Homeobox domain
DSBAPF013231930.0000349.800321377280382DSBA-like thioredoxin domain
interactor31.0000DUF494 (PF04361): Protein of unknown function (DUF494)
HNF-1_N (PF04814): Hepatocyte nuclear factor 1 (HNF-1), N terminus
Homeobox (PF00046): Homeobox domain
DSBA (PF01323): DSBA-like thioredoxin domain
Ikzf1

Domain structure obtained by HMM

Protein ID: XP_008847496.1 - DNA-binding protein Ikaros isoform X1
KEEG Ortholog ID: K09220
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ADK_lidPF05191360.012.200112123107124Adenylate kinase, active site lid
zf-metPF12874250.000003713.600118140117140Zinc-finger of C2H2 type
zf-H2C2_2PF13465260.00000000007128.600132155132156Zinc-finger double domain
zf-H2C2_2PF13465260.0000000001527.500159182159184Zinc-finger double domain
zf-H2C2_2PF13465260.00000001821.000187211187212Zinc-finger double domain
zf-C2H2PF00096230.00000008818.800201224201224Zinc finger, C2H2 type
Desulfoferrod_NPF06397360.0000768.600455465454466Desulfoferrodoxin, N-terminal domain
zf-C2H2_4PF13894240.00116.400460479460480C2H2-type zinc finger
zf-H2C2_2PF13465260.000766.400478495474497Zinc-finger double domain
zf-C2H2PF00096230.0000689.700488512488512Zinc finger, C2H2 type
oncogene, tumor suppressor31.0000ADK_lid (PF05191): Adenylate kinase, active site lid
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
zf-C2H2 (PF00096): Zinc finger, C2H2 type
Desulfoferrod_N (PF06397): Desulfoferrodoxin, N-terminal domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Kdm1a

Domain structure obtained by HMM

Protein ID: XP_008846795.1 - lysine-specific histone demethylase 1A
KEEG Ortholog ID: K11450
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF4298PF14131870.0171.50023521560Domain of unknown function (DUF4298)
ZapBPF06005710.0480.50037751681Cell division protein ZapB
SWIRMPF04433898.3e-2160.5009016882168SWIRM domain
Amino_oxidasePF015934514e-139450.700192729192730Flavin containing amine oxidoreductase
interactor60.4006.000DUF4298 (PF14131): Domain of unknown function (DUF4298)
ZapB (PF06005): Cell division protein ZapB
SWIRM (PF04433): SWIRM domain
Amino_oxidase (PF01593): Flavin containing amine oxidoreductase
LOC103727574

Domain structure obtained by HMM

Protein ID: XP_008823743.1 - golgin subfamily A member 2 isoform X7
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Atg14PF101863240.00771.40017531065Vacuolar sorting 38 and autophagy-related subunit 14
CENP-QPF130941550.0330.6005614015143CENP-Q, a CENPA-CAD centromere complex subunit
DUF2046PF097553040.00001310.600179246149256Uncharacterized conserved protein H4 (DUF2046)
BRE1PF08647950.0000569.500238328238336BRE1 E3 ubiquitin ligase
FliJPF020501230.00002410.800335406330410Flagellar FliJ protein
GOLGA2L5PF150706223.4e-303993.00038610043861004Putative golgin subfamily A member 2-like protein 5
interactor21.0000Atg14 (PF10186): Vacuolar sorting 38 and autophagy-related subunit 14
CENP-Q (PF13094): CENP-Q, a CENPA-CAD centromere complex subunit
DUF2046 (PF09755): Uncharacterized conserved protein H4 (DUF2046)
BRE1 (PF08647): BRE1 E3 ubiquitin ligase
FliJ (PF02050): Flagellar FliJ protein
GOLGA2L5 (PF15070): Putative golgin subfamily A member 2-like protein 5
LOC103735136

Domain structure obtained by HMM

Protein ID: XP_008832489.1 - heterogeneous nuclear ribonucleoprotein C-like
KEEG Ortholog ID: K12884
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
RRM_1PF00076701.4e-1646.40018801881RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_CPF118002060.000138.200174231165276Replication protein C C-terminal region
Stm1_NPF09598650.00923.200215237195239Stm1
Stm1_NPF09598650.013.100240251240275Stm1
interactor31.0000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_C (PF11800): Replication protein C C-terminal region
Stm1_N (PF09598): Stm1
Lzts2

Domain structure obtained by HMM

Protein ID: XP_008843797.1 - leucine zipper putative tumor suppressor 2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
CAP_NPF012133170.000001514.000265321260351Adenylate cyclase associated (CAP) N terminal
DUF4250PF14056550.000059.600319357318363Domain of unknown function (DUF4250)
ATG16PF086142030.0000769.100330413326415Autophagy protein 16 (ATG16)
DUF3287PF116901280.00002810.100397436369447Protein of unknown function (DUF3287)
CENP-F_leu_zipPF104731400.00003310.200412483409489Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Fez1PF068181987.3e-73231.400439635439636Fez1
DUF1127PF06568370.00000612.300625652622654Domain of unknown function (DUF1127)
tumor suppressor30.6671.000CAP_N (PF01213): Adenylate cyclase associated (CAP) N terminal
DUF4250 (PF14056): Domain of unknown function (DUF4250)
ATG16 (PF08614): Autophagy protein 16 (ATG16)
DUF3287 (PF11690): Protein of unknown function (DUF3287)
CENP-F_leu_zip (PF10473): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Fez1 (PF06818): Fez1
DUF1127 (PF06568): Domain of unknown function (DUF1127)
Mdfi

Domain structure obtained by HMM

Protein ID: XP_008821344.1 - myoD family inhibitor
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Herpes_LMP1PF052973860.00332.7005901149Herpesvirus latent membrane protein 1 (LMP1)
Herpes_UL56PF045341970.000001114.4004212215153Herpesvirus UL56 protein
MDFIPF153161839.5e-58181.6009924866248MyoD family inhibitor
interactor200Herpes_LMP1 (PF05297): Herpesvirus latent membrane protein 1 (LMP1)
Herpes_UL56 (PF04534): Herpesvirus UL56 protein
MDFI (PF15316): MyoD family inhibitor
Mtus2

Domain structure obtained by HMM

Protein ID: XP_008823272.1 - microtubule-associated tumor suppressor candidate 2 isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DivICPF04977800.000496.20035622864Septum formation initiator
DUF148PF025201090.00000214.20010818295186Domain of unknown function DUF148
DUF148PF025201090.0000459.800183248180252Domain of unknown function DUF148
Jnk-SapK_ap_NPF097441560.00001911.100212308207313JNK_SAPK-associated protein-1
RNA_pol_Rpb1_RPF05001140.0000008115.700317330317330RNA polymerase Rpb1 C-terminal repeat
tumor suppressor100DivIC (PF04977): Septum formation initiator
DUF148 (PF02520): Domain of unknown function DUF148
Jnk-SapK_ap_N (PF09744): JNK_SAPK-associated protein-1
RNA_pol_Rpb1_R (PF05001): RNA polymerase Rpb1 C-terminal repeat
Nt5c

Domain structure obtained by HMM

Protein ID: XP_008829655.1 - 5'(3')-deoxyribonucleotidase, cytosolic type
KEEG Ortholog ID: K01081
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
NT5CPF069411809.7e-2986.6001119572015' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
interactor100NT5C (PF06941): 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
Plscr1

Domain structure obtained by HMM

Protein ID: XP_008849578.1 - phospholipid scramblase 1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ScramblasePF038032219.2e-101321.800117337116337Scramblase
interactor30.6671.000Scramblase (PF03803): Scramblase
Pnma1

Domain structure obtained by HMM

Protein ID: XP_008847991.1 - paraneoplastic antigen Ma1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
PNMAPF148933301.4e-137444.60013241325PNMA
oncogene100PNMA (PF14893): PNMA
Rbpms

Domain structure obtained by HMM

Protein ID: XP_017654581.1 - RNA-binding protein with multiple splicing isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
RRM_1PF00076702.9e-1645.4004110241104RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
interactor50.5003.000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Sdcbp2

Domain structure obtained by HMM

Protein ID: XP_008832536.2 - syntenin-2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
PadRPF03551750.00002610.50031572664Transcriptional regulator PadR-like family
PadRPF03551750.00822.500748660101Transcriptional regulator PadR-like family
PDZPF00595820.0000000000001137.700142217141218PDZ domain (Also known as DHR or GLGF)
PDZPF00595820.000000001324.600226296225297PDZ domain (Also known as DHR or GLGF)
interactor200PadR (PF03551): Transcriptional regulator PadR-like family
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Sox5

Domain structure obtained by HMM

Protein ID: XP_008834454.1 - transcription factor SOX-5 isoform X1
KEEG Ortholog ID: K09269
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
MPS2PF170603720.000002812.900135271111296Monopolar spindle protein 2
SOARPF165331010.00001211.500454507446517STIM1 Orai1-activating region
HMG_boxPF00505691.4e-2679.000555623555623HMG (high mobility group) box
oncogene31.0000MPS2 (PF17060): Monopolar spindle protein 2
SOAR (PF16533): STIM1 Orai1-activating region
HMG_box (PF00505): HMG (high mobility group) box
Spert

Domain structure obtained by HMM

Protein ID: XP_008822621.1 - spermatid-associated protein isoform X1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ChibbyPF146451160.00000000000000342.9009419878201Chibby family
ZapBPF06005710.00653.300245271240333Cell division protein ZapB
LatarcinPF10279810.00001411.800319394315400Latarcin precursor
TPR_MLP1_2PF079261290.00003110.300356411352428TPR/MLP1/MLP2-like protein
ChibbyPF146451160.000138.600379430326430Chibby family
interactor200Chibby (PF14645): Chibby family
ZapB (PF06005): Cell division protein ZapB
Latarcin (PF10279): Latarcin precursor
TPR_MLP1_2 (PF07926): TPR/MLP1/MLP2-like protein
Suv39h1

Domain structure obtained by HMM

Protein ID: XP_008840769.1 - histone-lysine N-methyltransferase SUV39H1 isoform X1
KEEG Ortholog ID: K11419
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ChromoPF00385554.6e-1748.00043914392Chromo (CHRromatin Organisation MOdifier) domain
Pre-SETPF050331076.7e-2367.700141235136235Pre-SET motif
SETPF008561696.9e-2884.300255366255366SET domain
Pre-SETPF050331070.0670.200399408358410Pre-SET motif
interactor40.6671.000Chromo (PF00385): Chromo (CHRromatin Organisation MOdifier) domain
Pre-SET (PF05033): Pre-SET motif
SET (PF00856): SET domain
Tmcc2

Domain structure obtained by HMM

Protein ID: XP_017651149.1 - transmembrane and coiled-coil domains protein 2 isoform X1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
IncAPF041561900.00662.4007911577132IncA protein
DUF1690PF079561390.0261.2009514689163Protein of Unknown function (DUF1690)
Tmemb_cc2PF102673961.8e-143464.400282623282629Predicted transmembrane and coiled-coil 2 protein
HbrBPF085391690.00722.500699714692715HbrB-like
interactor31.0000IncA (PF04156): IncA protein
DUF1690 (PF07956): Protein of Unknown function (DUF1690)
Tmemb_cc2 (PF10267): Predicted transmembrane and coiled-coil 2 protein
HbrB (PF08539): HbrB-like
Traf1

Domain structure obtained by HMM

Protein ID: XP_008831687.1 - TNF receptor-associated factor 1
KEEG Ortholog ID: K03172
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
zf-C4H2PF101462020.021.3001958261Zinc finger-containing protein
TRAF_BIRC3_bdPF16673642.6e-2161.600186243181244TNF receptor-associated factor BIRC3 binding domain
SlyXPF04102670.000477.100231261223267SlyX
oncogene200zf-C4H2 (PF10146): Zinc finger-containing protein
TRAF_BIRC3_bd (PF16673): TNF receptor-associated factor BIRC3 binding domain
SlyX (PF04102): SlyX
Traf4

Domain structure obtained by HMM

Protein ID: XP_008826911.1 - TNF receptor-associated factor 4
KEEG Ortholog ID: K09848
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
zf-C3HC4PF00097410.000000000007231.40018551856Zinc finger, C3HC4 type (RING finger)
SinaPF031452000.0000008515.3008313372137Seven in absentia protein family
zf-TRAFPF02176602.5e-2059.300102156102156TRAF-type zinc finger
zf-TRAFPF02176600.0000000000003336.500156210156210TRAF-type zinc finger
zf-TRAFPF02176608.8e-2676.700210269210269TRAF-type zinc finger
SinaPF031452000.00214.200249276238348Seven in absentia protein family
MATHPF009171130.00174.800355414327424MATH domain
MATHPF009171130.0000469.800431463412464MATH domain
oncogene50.5003.000zf-C3HC4 (PF00097): Zinc finger, C3HC4 type (RING finger)
Sina (PF03145): Seven in absentia protein family
zf-TRAF (PF02176): TRAF-type zinc finger
MATH (PF00917): MATH domain
Trim27

Domain structure obtained by HMM

Protein ID: XP_008826545.1 - zinc finger protein RFP isoform X2
KEEG Ortholog ID: K12009
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Prok-RING_4PF14447460.00353.600922727Prokaryotic RING finger family 4
zf-C3HC4_4PF15227420.00000000000001340.40016561656zinc finger of C3HC4-type, RING
zf-AN1PF01428400.000257.50042703171AN1-like Zinc finger
zf-B_boxPF00643425.7e-1644.8009313291132B-box zinc finger
LebercilinPF156191930.00134.600134206131211Ciliary protein causing Leber congenital amaurosis disease
IncAPF041561900.000128.000228311223317IncA protein
PRYPF13765495.5e-2676.300318366318366SPRY-associated domain
SPRYPF006221202e-2575.500370479370487SPRY domain
oncogene31.0000Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
zf-AN1 (PF01428): AN1-like Zinc finger
zf-B_box (PF00643): B-box zinc finger
Lebercilin (PF15619): Ciliary protein causing Leber congenital amaurosis disease
IncA (PF04156): IncA protein
PRY (PF13765): SPRY-associated domain
SPRY (PF00622): SPRY domain

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