Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adgrl2 (from a repository: Sat Apr 21 11:01:18 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins2 (20.00 %)
The number (and %) of the tumor suppressors2 (20.00 %)
Total number of binary PPIs (saturation %)12 (26.67 %)
The number (and %) of affected PPIs9 (75.00 %)
PPI diameter2
PPI radius1
The average degree of PPI1.800
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients10 (100.00 %)
The number (and %) of a zero Betweenness Centrality9 (90.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adgrl2
user protein, oncogene9072.000Gal_Lectin (PF02140): Galactose binding lectin domain
OLF (PF02191): Olfactomedin-like domain
HRM (PF02793): Hormone receptor domain
GAIN (PF16489): GPCR-Autoproteolysis INducing (GAIN) domain
GPS (PF01825): GPCR proteolysis site, GPS, motif
7tm_2 (PF00002): 7 transmembrane receptor (Secretin family)
zf-C2HCIx2C (PF10782): Zinc-finger
Latrophilin (PF02354): Latrophilin Cytoplasmic C-terminal region
Cln3
interactor100CLN3 (PF02487): CLN3 protein
Ctdspl
tumor suppressor100NIF (PF03031): NLI interacting factor-like phosphatase
Flrt1
interactor100LRRNT (PF01462): Leucine rich repeat N-terminal domain
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
LRRCT (PF01463): Leucine rich repeat C-terminal domain
fn3 (PF00041): Fibronectin type III domain
Irf3
tumor suppressor200IRF (PF00605): Interferon regulatory factor transcription factor
IRF-3 (PF10401): Interferon-regulatory factor 3
Nck1
oncogene100SH3_1 (PF00018): SH3 domain
SH3_9 (PF14604): Variant SH3 domain
SH2 (PF00017): SH2 domain
Ntrk1
oncogene200LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Shank1
interactor200FERM_f0 (PF16511): N-terminal or F0 domain of Talin-head FERM
Ank_2 (PF12796): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RSRP (PF17069): Arginine/Serine-Rich protein 1
SH3_2 (PF07653): Variant SH3 domain
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Mito_fiss_reg (PF05308): Mitochondrial fission regulator
CAP_N (PF01213): Adenylate cyclase associated (CAP) N terminal
SAM_1 (PF00536): SAM domain (Sterile alpha motif)
Tmem17
interactor100Transmemb_17 (PF09799): Predicted membrane protein
DUF3043 (PF11241): Protein of unknown function (DUF3043)
Tmem216
interactor100Transmemb_17 (PF09799): Predicted membrane protein

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