Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adgrl1 (from a repository: Thu Apr 19 20:59:48 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)20
The number (and %) of the onco-proteins1 (5.00 %)
The number (and %) of the tumor suppressors1 (5.00 %)
Total number of binary PPIs (saturation %)26 (13.68 %)
The number (and %) of affected PPIs19 (73.08 %)
PPI diameter2
PPI radius1
The average degree of PPI2.100
Assortativity coefficient-0.5966
The network average Clustering coefficient0.134
The number (and %) of a zero Clustering coefficients16 (80.00 %)
The number (and %) of a zero Betweenness Centrality18 (90.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adgrl1
user protein190.012337.000Gal_Lectin (PF02140): Galactose binding lectin domain
OLF (PF02191): Olfactomedin-like domain
HRM (PF02793): Hormone receptor domain
GAIN (PF16489): GPCR-Autoproteolysis INducing (GAIN) domain
GPS (PF01825): GPCR proteolysis site, GPS, motif
7tm_2 (PF00002): 7 transmembrane receptor (Secretin family)
Latrophilin (PF02354): Latrophilin Cytoplasmic C-terminal region
Apc
oncogene, tumor suppressor200APC_N_CC (PF16689): Coiled-coil N-terminus of APC, dimerisation domain
SAS4 (PF15460): Something about silencing, SAS, complex subunit 4
Suppressor_APC (PF11414): Adenomatous polyposis coli tumour suppressor protein
DUF972 (PF06156): Protein of unknown function (DUF972)
Arm (PF00514): Armadillo/beta-catenin-like repeat
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_15aa (PF05972): APC 15 residue motif
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_r (PF05923): APC repeat
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
SAMP (PF05924): SAMP Motif
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_basic (PF05956): APC basic domain
EB1_binding (PF05937): EB-1 Binding Domain
Atp6v0d1
interactor100vATP-synt_AC39 (PF01992): ATP synthase (C/AC39) subunit
B4gat1
interactor100GspL_C (PF12693): GspL periplasmic domain
Glyco_transf_49 (PF13896): Glycosyl-transferase for dystroglycan
Cacna1a
interactor100Fungus-induced (PF10917): Fungus-induced protein
Ion_trans (PF00520): Ion transport protein
PNK3P (PF08645): Polynucleotide kinase 3 phosphatase
GPHH (PF16905): Voltage-dependent L-type calcium channel, IQ-associated
Ca_chan_IQ (PF08763): Voltage gated calcium channel IQ domain
SelP_N (PF04592): Selenoprotein P, N terminal region
Cd1b
interactor100MHC_I_3 (PF16497): MHC-I family domain
Ig_3 (PF13927): Immunoglobulin domain
C1-set (PF07654): Immunoglobulin C1-set domain
Edil3
interactor100EGF (PF00008): EGF-like domain
F5_F8_type_C (PF00754): F5/8 type C domain
Elavl1
oncogene31.0000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fam189a2
interactor100CD20 (PF04103): CD20-like family
Flrt1
interactor100LRRNT (PF01462): Leucine rich repeat N-terminal domain
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
LRRCT (PF01463): Leucine rich repeat C-terminal domain
fn3 (PF00041): Fibronectin type III domain
Gpr21
interactor1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
LOC103732400
interactor100UL45 (PF05473): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059): Lectin C-type domain
LOC103736087
interactor200Cadherin_2 (PF08266): Cadherin-like
Cadherin_3 (PF16184): Cadherin-like
Cadherin (PF00028): Cadherin domain
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
LOC103736112
interactor200Cadherin_2 (PF08266): Cadherin-like
Cadherin (PF00028): Cadherin domain
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
Nrg1
interactor100I-set (PF07679): Immunoglobulin I-set domain
EGF (PF00008): EGF-like domain
Neuregulin (PF02158): Neuregulin family
Nrn1
interactor100NRN1 (PF15056): Neuritin protein family
Psma3
interactor200Proteasome_A_N (PF10584): Proteasome subunit A N-terminal signature
Proteasome (PF00227): Proteasome subunit
Tmem30a
interactor30.6671.000CDC50 (PF03381): LEM3 (ligand-effect modulator 3) family / CDC50 family
Tmem30b
interactor21.0000CDC50 (PF03381): LEM3 (ligand-effect modulator 3) family / CDC50 family
Upk1a
interactor100Tetraspannin (PF00335): Tetraspanin family

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