Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adcy8 (from a repository: Mon Apr 16 19:24:04 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)3
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors1 (33.33 %)
Total number of binary PPIs (saturation %)3 (100.00 %)
The number (and %) of affected PPIs2 (66.67 %)
PPI diameter2
PPI radius1
The average degree of PPI1.333
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients3 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (66.67 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure		 Type Number
of PPI (degree)		 Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam ID): description
Adcy8

Domain structure obtained by HMM

Protein ID: XP_008843712.1 - adenylate cyclase type 8 isoform X1
KEEG Ortholog ID: K08048
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Herpes_PAPPF033253180.0071.6005012441134Herpesvirus polymerase accessory protein
AC_NPF162144156.2e-40123.600158394124400Adenylyl cyclase N-terminal extracellular and transmembrane region
Guanylate_cycPF002111834e-62195.200405587404588Adenylate and Guanylate cyclase catalytic domain
DUF1053PF063271035.5e-3296.700616711616711Domain of Unknown Function (DUF1053)
DUF4131PF135671760.00253.600857923827941Domain of unknown function (DUF4131)
Guanylate_cycPF002111832.2e-69218.90097311709721171Adenylate and Guanylate cyclase catalytic domain
user protein202.000Herpes_PAP (PF03325): Herpesvirus polymerase accessory protein
AC_N (PF16214): Adenylyl cyclase N-terminal extracellular and transmembrane region
Guanylate_cyc (PF00211): Adenylate and Guanylate cyclase catalytic domain
DUF1053 (PF06327): Domain of Unknown Function (DUF1053)
DUF4131 (PF13567): Domain of unknown function (DUF4131)
Calm2

Domain structure obtained by HMM

Protein ID: XP_008821273.1 - calmodulin
KEEG Ortholog ID: K02183
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
EF-hand_7PF13499718.9e-2057.30013731074EF-hand domain pair
EF-hand_7PF13499712.9e-2368.5008314683147EF-hand domain pair
interactor100EF-hand_7 (PF13499): EF-hand domain pair
Cftr

Domain structure obtained by HMM

Protein ID: XP_008835436.1 - cystic fibrosis transmembrane conductance regulator
KEEG Ortholog ID: K05031
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ABC_membranePF006642742.3e-44138.2007133870339ABC transporter transmembrane region
AAA_15PF131753840.0290.000357416352427AAA ATPase domain
ABC_tranPF000051374.8e-2884.600430564430565ABC transporter
SMC_NPF024632200.000485.700536606506613RecF/RecN/SMC N terminal domain
CFTR_RPF143962132.9e-95303.900628836628836Cystic fibrosis TM conductance regulator (CFTR), regulator domain
ABC_membranePF006642745e-57179.70085011348491134ABC transporter transmembrane region
ABC_tranPF000051376.5e-36110.1001214136112141361ABC transporter
AAA_21PF133043030.000000815.2001331138213051387AAA domain, putative AbiEii toxin, Type IV TA system
AAA_23PF134762000.0142.1001418146013481466AAA domain
tumor suppressor200ABC_membrane (PF00664): ABC transporter transmembrane region
AAA_15 (PF13175): AAA ATPase domain
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
CFTR_R (PF14396): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
AAA_21 (PF13304): AAA domain, putative AbiEii toxin, Type IV TA system
AAA_23 (PF13476): AAA domain

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