Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adcy6 (from a repository: Fri Apr 13 02:20:23 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins2 (14.29 %)
The number (and %) of the tumor suppressors1 (7.14 %)
Total number of binary PPIs (saturation %)19 (20.88 %)
The number (and %) of affected PPIs13 (68.42 %)
PPI diameter2
PPI radius1
The average degree of PPI2.286
Assortativity coefficient-0.4237
The network average Clustering coefficient0.431
The number (and %) of a zero Clustering coefficients7 (50.00 %)
The number (and %) of a zero Betweenness Centrality13 (92.86 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adcy6
user protein130.038150.000AC_N (PF16214): Adenylyl cyclase N-terminal extracellular and transmembrane region
Guanylate_cyc (PF00211): Adenylate and Guanylate cyclase catalytic domain
DUF1053 (PF06327): Domain of Unknown Function (DUF1053)
DUF2207 (PF09972): Predicted membrane protein (DUF2207)
Shisa (PF13908): Wnt and FGF inhibitory regulator
HNOBA (PF07701): Heme NO binding associated
Ankmy2
interactor100Ank_2 (PF12796): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_3 (PF13606): Ankyrin repeat
zf-C6H2 (PF15801): zf-MYND-like zinc finger, mRNA-binding
zf-MYND (PF01753): MYND finger
Atxn1
interactor31.0000ATXN-1_C (PF12547): Capicua transcriptional repressor modulator
AXH (PF08517): Ataxin-1 and HBP1 module (AXH)
B4gat1
interactor100GspL_C (PF12693): GspL periplasmic domain
Glyco_transf_49 (PF13896): Glycosyl-transferase for dystroglycan
Cav1
oncogene, tumor suppressor21.0000Caveolin (PF01146): Caveolin
Cd70
interactor100TNF (PF00229): TNF(Tumour Necrosis Factor) family
Gdpd5
interactor100zf-DHHC (PF01529): DHHC palmitoyltransferase
DUF4407 (PF14362): Domain of unknown function (DUF4407)
GDPD (PF03009): Glycerophosphoryl diester phosphodiesterase family
GDPD_2 (PF13653): Glycerophosphoryl diester phosphodiesterase family
Gnas
oncogene200Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
NUFIP2 (PF15293): Nuclear fragile X mental retardation-interacting protein 2
G-alpha (PF00503): G-protein alpha subunit
Ippk
interactor21.0000Ins_P5_2-kin (PF06090): Inositol-pentakisphosphate 2-kinase
LOC103748066
interactor21.0000Neur_chan_LBD (PF02931): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
Lgals3
oncogene31.0000Gal-bind_lectin (PF00337): Galactoside-binding lectin
Lgals8
interactor100Gal-bind_lectin (PF00337): Galactoside-binding lectin
Syne4
interactor100Spectrin (PF00435): Spectrin repeat
KASH (PF10541): Nuclear envelope localisation domain
Yipf3
interactor21.0000Yip1 (PF04893): Yip1 domain
DUF4133 (PF13571): Domain of unknown function (DUF4133)

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