Find Protein-Protein Interactions (PPI) Network

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Protein/NCBI_ID(s): Refseq_ID(s): KEGG_KO(s):	Adat3
Level of PPIs:		or Upload text file:	Update repository

Visible interactions:

Visible interactors:

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Visualization interactions

Cytoscape.js taxid = 1026970 for: protein(s) Adat3 (from a repository: Fri Apr 13 09:20:27 2018)

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Statistics and Network structure information

Statistics of PPI	Value(s)
The number of interactors (fusion and proteins)	3
The number (and %) of the onco-proteins	0 (0.00 %)
The number (and %) of the tumor suppressors	1 (33.33 %)
Total number of binary PPIs (saturation %)	4 (133.33 %)
The number (and %) of affected PPIs	2 (50.00 %)
PPI diameter	2
PPI radius	1
The average degree of PPI	1.333
Assortativity coefficient	0
The network average Clustering coefficient	0.000
The number (and %) of a zero Clustering coefficients	3 (100.00 %)
The number (and %) of a zero Betweenness Centrality	2 (66.67 %)

ACTIVE INTERACTORS

List of active interactors

Interactor,
Domain structure

Type

Number
of PPI (degree)

Clustering
Coefficient

Betweenness
Centrality

Domains (Pfam ID): description

Adat3

XP_008835351.1

Domain structure obtained by HMM

Protein ID: XP_008835351.1 - probable inactive tRNA-specific adenosine deaminase-like protein 3
KEEG Ortholog ID: K15442

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
DUF1525	PF07511	114	0.0000091	12.100	143	195	131	201	Protein of unknown function (DUF1525)
dCMP_cyt_deam_1	PF00383	101	1.9e-17	49.400	167	304	163	305	Cytidine and deoxycytidylate deaminase zinc-binding region
MafB19-deam	PF14437	138	0.000000000016	30.400	279	339	273	342	MafB19-like deaminase

user protein

2.000

DUF1525 (PF07511): Protein of unknown function (DUF1525)
dCMP_cyt_deam_1 (PF00383): Cytidine and deoxycytidylate deaminase zinc-binding region
MafB19-deam (PF14437): MafB19-like deaminase

Kat2a

XP_008833507.1

Domain structure obtained by HMM

Protein ID: XP_008833507.1 - histone acetyltransferase KAT2A isoform X1
KEEG Ortholog ID: K06062

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
NICE-1	PF15845	89	0.011	2.800	34	72	31	95	Cysteine-rich C-terminal 1 family
PCAF_N	PF06466	251	1.1e-120	388.000	84	334	84	334	PCAF (P300/CBP-associated factor) N-terminal domain
Acetyltransf_1	PF00583	117	0.000000000000097	37.900	542	626	516	626	Acetyltransferase (GNAT) family
Bromodomain	PF00439	84	1.9e-26	78.300	736	817	736	819	Bromodomain

interactor

NICE-1 (PF15845): Cysteine-rich C-terminal 1 family
PCAF_N (PF06466): PCAF (P300/CBP-associated factor) N-terminal domain
Acetyltransf_1 (PF00583): Acetyltransferase (GNAT) family
Bromodomain (PF00439): Bromodomain

Thrb

XP_008831368.1

Domain structure obtained by HMM

Protein ID: XP_008831368.1 - thyroid hormone receptor beta isoform X1
KEEG Ortholog ID: K08362

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
zf-C4	PF00105	70	7.2e-34	102.400	106	175	105	176	Zinc finger, C4 type (two domains)
Hormone_recep	PF00104	208	1.6e-21	63.000	269	439	265	445	Ligand-binding domain of nuclear hormone receptor

tumor suppressor

zf-C4 (PF00105): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104): Ligand-binding domain of nuclear hormone receptor

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