Find Protein-Protein Interactions (PPI) Network

Choose & Enter
Choose animal: Visualization driver:
Protein/NCBI_ID(s):
Refseq_ID(s):
KEGG_KO(s):


Level of PPIs:
or Upload text file:
Update repository

Visible interactions: Visible interactors: Size of node:

Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adarb1 (from a repository: Wed Apr 11 12:04:25 2018)
Examples

Layout Breadthfirst

Circle

Concentric

Cose

Grid

Random
Export graph PNG file
JPG file
JSON file

Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)20
The number (and %) of the onco-proteins4 (20.00 %)
The number (and %) of the tumor suppressors2 (10.00 %)
Total number of binary PPIs (saturation %)38 (20.00 %)
The number (and %) of affected PPIs19 (50.00 %)
PPI diameter2
PPI radius1
The average degree of PPI3.400
Assortativity coefficient-0.5319
The network average Clustering coefficient0.474
The number (and %) of a zero Clustering coefficients7 (35.00 %)
The number (and %) of a zero Betweenness Centrality13 (65.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adarb1
user protein, tumor suppressor190.088300.500dsrm (PF00035): Double-stranded RNA binding motif
A_deamin (PF02137): Adenosine-deaminase (editase) domain
Adgre5
oncogene100EGF_MSP1_1 (PF12946): MSP1 EGF domain 1
cEGF (PF12662): Complement Clr-like EGF-like
EGF_CA (PF07645): Calcium-binding EGF domain
GAIN (PF16489): GPCR-Autoproteolysis INducing (GAIN) domain
GPS (PF01825): GPCR proteolysis site, GPS, motif
7tm_2 (PF00002): 7 transmembrane receptor (Secretin family)
Sre (PF03125): C. elegans Sre G protein-coupled chemoreceptor
App
interactor50.5003.000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Bmi1
oncogene50.5002.000zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207): RAWUL domain RING finger- and WD40-associated ubiquitin-like
Brix1
interactor41.0000Brix (PF04427): Brix domain
Ccdc124
interactor100Cir_N (PF10197): N-terminal domain of CBF1 interacting co-repressor CIR
AAA_17 (PF13207): AAA domain
DUF1014 (PF06244): Protein of unknown function (DUF1014)
Ebna1bp2
interactor41.0000Ebp2 (PF05890): Eukaryotic rRNA processing protein EBP2
Hnrnpa1
interactor60.4005.000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627): Nuclear factor hnRNPA1
Ifrd2
oncogene21.0000IFRD (PF05004): Interferon-related developmental regulator (IFRD)
IFRD_C (PF04836): Interferon-related protein conserved region
Lrpprc
interactor30.6670.500PPR_3 (PF13812): Pentatricopeptide repeat domain
PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
MA3 (PF02847): MA3 domain
PPR (PF01535): PPR repeat
TPR_19 (PF14559): Tetratricopeptide repeat
PPR_2 (PF13041): PPR repeat family
Nifk
interactor41.0000NINJA_B (PF16136): Putative nuclear localisation signal
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
hNIFK_binding (PF12196): FHA Ki67 binding domain of hNIFK
Pin1
tumor suppressor100WW (PF00397): WW domain
Rotamase (PF00639): PPIC-type PPIASE domain
Ppp2cb
tumor suppressor100STPPase_N (PF16891): Serine-threonine protein phosphatase N-terminal domain
Metallophos (PF00149): Calcineurin-like phosphoesterase
Rrs1
interactor41.0000RRS1 (PF04939): Ribosome biogenesis regulatory protein (RRS1)
RR_TM4-6 (PF06459): Ryanodine Receptor TM 4-6
Sdad1
interactor100NUC130_3NT (PF08158): NUC130/3NT domain
YL1 (PF05764): YL1 nuclear protein
Tmemb_18A (PF09771): Transmembrane protein 188
SDA1 (PF05285): SDA1
Strbp
interactor30.6670.500DUF936 (PF06075): Plant protein of unknown function (DUF936)
DZF (PF07528): DZF domain
dsrm (PF00035): Double-stranded RNA binding motif
Tcf20
interactor100G0-G1_switch_2 (PF15103): G0/G1 switch protein 2
IncA (PF04156): IncA protein
DUF2360 (PF10152): Predicted coiled-coil domain-containing protein (DUF2360)
tRNA_synt_1c_R2 (PF04557): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
RBM39linker (PF15519): linker between RRM2 and RRM3 domains in RBM39 protein
DUF3484 (PF11983): Membrane-attachment and polymerisation-promoting switch
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
Usp39
oncogene21.0000zf-UBP (PF02148): Zn-finger in ubiquitin-hydrolases and other protein
UCH (PF00443): Ubiquitin carboxyl-terminal hydrolase
Wwp2
interactor200WW (PF00397): WW domain
HECT (PF00632): HECT-domain (ubiquitin-transferase)
Zfr
interactor30.6670.500Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
K_channel_TID (PF07941): Potassium channel Kv1.4 tandem inactivation domain
TAT_signal (PF10518): TAT (twin-arginine translocation) pathway signal sequence
zf-met (PF12874): Zinc-finger of C2H2 type
ANAPC_CDC26 (PF10471): Anaphase-promoting complex APC subunit CDC26
DZF (PF07528): DZF domain

B a c k    t o    T o p ⇑