Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adap2 (from a repository: Sat Apr 14 03:28:33 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors2 (20.00 %)
Total number of binary PPIs (saturation %)19 (42.22 %)
The number (and %) of affected PPIs9 (47.37 %)
PPI diameter2
PPI radius1
The average degree of PPI2.400
Assortativity coefficient-0.5122
The network average Clustering coefficient0.342
The number (and %) of a zero Clustering coefficients5 (50.00 %)
The number (and %) of a zero Betweenness Centrality7 (70.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adap2
user protein90.08364.000ArfGap (PF01412): Putative GTPase activating protein for Arf
PH (PF00169): PH domain
App
interactor40.6671.000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Eef1g
interactor200GST_N (PF02798): Glutathione S-transferase, N-terminal domain
GST_C (PF00043): Glutathione S-transferase, C-terminal domain
EF1G (PF00647): Elongation factor 1 gamma, conserved domain
Ikbkg
interactor200NEMO (PF11577): NF-kappa-B essential modulator NEMO
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
Golgin_A5 (PF09787): Golgin subfamily A member 5
CC2-LZ (PF16516): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
LLC1 (PF14945): Normal lung function maintenance, Low in Lung Cancer 1 protein
Kctd10
interactor100BTB_2 (PF02214): BTB/POZ domain
Ncl
interactor200PBP1_TM (PF14812): Transmembrane domain of transglycosylase PBP1 at N-terminal
YL1 (PF05764): YL1 nuclear protein
Myc_N (PF01056): Myc amino-terminal region
ANAPC15 (PF15243): Anaphase-promoting complex subunit 15
Sigma70_ner (PF04546): Sigma-70, non-essential region
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608): Limkain b1
Nedd4l
oncogene, tumor suppressor31.0000C2 (PF00168): C2 domain
WW (PF00397): WW domain
HECT (PF00632): HECT-domain (ubiquitin-transferase)
Prnp
interactor100Prion_bPrPp (PF11587): Major prion protein bPrPp - N terminal
Prion_octapep (PF03991): Copper binding octapeptide repeat
Glt_symporter (PF03616): Sodium/glutamate symporter
Prion (PF00377): Prion/Doppel alpha-helical domain
Ranbp9
tumor suppressor31.0000SPRY (PF00622): SPRY domain
LisH (PF08513): LisH
CLTH (PF10607): CTLH/CRA C-terminal to LisH motif domain
Snca
interactor40.6671.000Synuclein (PF01387): Synuclein

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