Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adap1 (from a repository: Fri Apr 20 03:46:57 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)15
The number (and %) of the onco-proteins2 (13.33 %)
The number (and %) of the tumor suppressors5 (33.33 %)
Total number of binary PPIs (saturation %)27 (25.71 %)
The number (and %) of affected PPIs14 (51.85 %)
PPI diameter2
PPI radius1
The average degree of PPI2.267
Assortativity coefficient-0.7963
The network average Clustering coefficient0.236
The number (and %) of a zero Clustering coefficients10 (66.67 %)
The number (and %) of a zero Betweenness Centrality13 (86.67 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adap1
user protein140.033173.000ArfGap (PF01412): Putative GTPase activating protein for Arf
PH (PF00169): PH domain
Anp32a
oncogene, tumor suppressor100LRR_4 (PF12799): Leucine Rich repeats (2 copies)
LRR_9 (PF14580): Leucine-rich repeat
SDA1 (PF05285): SDA1
Csnk1a1
oncogene, tumor suppressor200Pkinase (PF00069): Protein kinase domain
Dvl3
interactor200DIX (PF00778): DIX domain
Dishevelled (PF02377): Dishevelled specific domain
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
DEP (PF00610): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dsh_C (PF12316): Segment polarity protein dishevelled (Dsh) C terminal
Gsk3b
oncogene, tumor suppressor31.0000Pkinase (PF00069): Protein kinase domain
LOC103727574
interactor100Atg14 (PF10186): Vacuolar sorting 38 and autophagy-related subunit 14
CENP-Q (PF13094): CENP-Q, a CENPA-CAD centromere complex subunit
DUF2046 (PF09755): Uncharacterized conserved protein H4 (DUF2046)
BRE1 (PF08647): BRE1 E3 ubiquitin ligase
FliJ (PF02050): Flagellar FliJ protein
GOLGA2L5 (PF15070): Putative golgin subfamily A member 2-like protein 5
Ncl
interactor31.0000PBP1_TM (PF14812): Transmembrane domain of transglycosylase PBP1 at N-terminal
YL1 (PF05764): YL1 nuclear protein
Myc_N (PF01056): Myc amino-terminal region
ANAPC15 (PF15243): Anaphase-promoting complex subunit 15
Sigma70_ner (PF04546): Sigma-70, non-essential region
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608): Limkain b1
Pik3ca
oncogene100PI3K_p85B (PF02192): PI3-kinase family, p85-binding domain
PI3K_rbd (PF00794): PI3-kinase family, ras-binding domain
PI3K_C2 (PF00792): Phosphoinositide 3-kinase C2
PI3Ka (PF00613): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
DUF2321 (PF10083): Uncharacterized protein conserved in bacteria (DUF2321)
PI3_PI4_kinase (PF00454): Phosphatidylinositol 3- and 4-kinase
Prkce
tumor suppressor200C2 (PF00168): C2 domain
PP_M1 (PF03012): Phosphoprotein
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
Pkinase (PF00069): Protein kinase domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Prkci
interactor21.0000PB1 (PF00564): PB1 domain
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
Pkinase (PF00069): Protein kinase domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Prkcz
interactor50.5003.000PB1 (PF00564): PB1 domain
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
Pkinase (PF00069): Protein kinase domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Prkd1
oncogene200C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
PH (PF00169): PH domain
Pkinase (PF00069): Protein kinase domain
Psme3
interactor200PA28_alpha (PF02251): Proteasome activator pa28 alpha subunit
PA28_beta (PF02252): Proteasome activator pa28 beta subunit
Ranbp9
tumor suppressor200SPRY (PF00622): SPRY domain
LisH (PF08513): LisH
CLTH (PF10607): CTLH/CRA C-terminal to LisH motif domain
Sdcbp2
interactor200PadR (PF03551): Transcriptional regulator PadR-like family
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)

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