Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adamts12 (from a repository: Mon Apr 16 21:16:04 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins1 (9.09 %)
The number (and %) of the tumor suppressors1 (9.09 %)
Total number of binary PPIs (saturation %)12 (21.82 %)
The number (and %) of affected PPIs10 (83.33 %)
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5164
The network average Clustering coefficient0.184
The number (and %) of a zero Clustering coefficients8 (72.73 %)
The number (and %) of a zero Betweenness Centrality10 (90.91 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adamts12
user protein100.02288.000Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
TSP_1 (PF00090): Thrombospondin type 1 domain
ADAM_spacer1 (PF05986): ADAM-TS Spacer 1
PLAC (PF08686): PLAC (protease and lacunin) domain
Calm2
interactor100EF-hand_7 (PF13499): EF-hand domain pair
Fkbp9
interactor100FKBP_C (PF00254): FKBP-type peptidyl-prolyl cis-trans isomerase
EF-hand_7 (PF13499): EF-hand domain pair
Meox2
interactor100SelP_N (PF04592): Selenoprotein P, N terminal region
Homeobox (PF00046): Homeobox domain
Myl6
interactor100EF-hand_6 (PF13405): EF-hand domain
EF-hand_8 (PF13833): EF-hand domain pair
EF-hand_7 (PF13499): EF-hand domain pair
Ppm1a
tumor suppressor100PP2C (PF00481): Protein phosphatase 2C
PP2C_C (PF07830): Protein serine/threonine phosphatase 2C, C-terminal domain
Snrk
interactor100Pkinase (PF00069): Protein kinase domain
Sp3
interactor100ANAPC_CDC26 (PF10471): Anaphase-promoting complex APC subunit CDC26
DUF1610 (PF07754): Domain of unknown function (DUF1610)
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
Ubr1
interactor100zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-UBR (PF02207): Putative zinc finger in N-recognin (UBR box)
ClpS (PF02617): ATP-dependent Clp protease adaptor protein ClpS
zf-RING_5 (PF14634): zinc-RING finger domain
zf-RING_2 (PF13639): Ring finger domain
Usf1
oncogene31.0000HLH (PF00010): Helix-loop-helix DNA-binding domain
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
Usf2
interactor21.0000HLH (PF00010): Helix-loop-helix DNA-binding domain
DUF2100 (PF09873): Uncharacterized protein conserved in archaea (DUF2100)

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