Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adamts1 (from a repository: Fri May 11 04:01:28 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins1 (7.14 %)
The number (and %) of the tumor suppressors1 (7.14 %)
Total number of binary PPIs (saturation %)16 (17.58 %)
The number (and %) of affected PPIs13 (81.25 %)
PPI diameter2
PPI radius1
The average degree of PPI1.857
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients14 (100.00 %)
The number (and %) of a zero Betweenness Centrality13 (92.86 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adamts1
user protein, oncogene130156.000Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
TSP_1 (PF00090): Thrombospondin type 1 domain
ADAM_spacer1 (PF05986): ADAM-TS Spacer 1
Adam32
interactor100Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
Disintegrin (PF00200): Disintegrin
ADAM_CR (PF08516): ADAM cysteine-rich
EGF_2 (PF07974): EGF-like domain
Cep250
interactor100AATF-Che1 (PF13339): Apoptosis antagonizing transcription factor
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
FlaC_arch (PF05377): Flagella accessory protein C (FlaC)
Alanine_zipper (PF11839): Alanine-zipper, major outer membrane lipoprotein
DUF4404 (PF14357): Domain of unknown function (DUF4404)
APG6 (PF04111): Autophagy protein Apg6
DUF724 (PF05266): Protein of unknown function (DUF724)
CENP-F_leu_zip (PF10473): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
DUF3584 (PF12128): Protein of unknown function (DUF3584)
Cnn_1N (PF07989): Centrosomin N-terminal motif 1
HIP1_clath_bdg (PF16515): Clathrin-binding domain of Huntingtin-interacting protein 1
Fib_alpha (PF08702): Fibrinogen alpha/beta chain family
DUF4472 (PF14739): Domain of unknown function (DUF4472)
Med9 (PF07544): RNA polymerase II transcription mediator complex subunit 9
ATG16 (PF08614): Autophagy protein 16 (ATG16)
HAUS-augmin3 (PF14932): HAUS augmin-like complex subunit 3
DUF1664 (PF07889): Protein of unknown function (DUF1664)
Pox_A_type_inc (PF04508): Viral A-type inclusion protein repeat
TPR_MLP1_2 (PF07926): TPR/MLP1/MLP2-like protein
SlyX (PF04102): SlyX
Spc7 (PF08317): Spc7 kinetochore protein
Reo_sigmaC (PF04582): Reovirus sigma C capsid protein
DUF2407_C (PF13373): DUF2407 C-terminal domain
CP12 (PF02672): CP12 domain
DUF641 (PF04859): Plant protein of unknown function (DUF641)
Bacillus_HBL (PF05791): Bacillus haemolytic enterotoxin (HBL)
PKcGMP_CC (PF16808): Coiled-coil N-terminus of cGMP-dependent protein kinase
Fez1 (PF06818): Fez1
DUF630 (PF04783): Protein of unknown function (DUF630)
Cer1
interactor100DAN (PF03045): DAN domain
Hpx
interactor100Hemopexin (PF00045): Hemopexin
Igfbp1
oncogene100IGFBP (PF00219): Insulin-like growth factor binding protein
Thyroglobulin_1 (PF00086): Thyroglobulin type-1 repeat
Klk1
interactor100Trypsin (PF00089): Trypsin
LOC103736148
interactor200Interferon (PF00143): Interferon alpha/beta domain
DIRP (PF06584): DIRP
LOC103745223
interactor200A2M_N (PF01835): MG2 domain
Big_3_5 (PF16640): Bacterial Ig-like domain (group 3)
A2M_N_2 (PF07703): Alpha-2-macroglobulin family N-terminal region
A2M (PF00207): Alpha-2-macroglobulin family
SVA (PF05326): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569): Alpha-macro-globulin thiol-ester bond-forming region
A2M_comp (PF07678): A-macroglobulin complement component
A2M_recep (PF07677): A-macroglobulin receptor
Napsa
interactor100Asp (PF00026): Eukaryotic aspartyl protease
Pla2g12b
interactor100PLA2G12 (PF06951): Group XII secretory phospholipase A2 precursor (PLA2G12)
Pla2g1b
interactor100Phospholip_A2_1 (PF00068): Phospholipase A2
Prss50
interactor100Trypsin (PF00089): Trypsin
Vegfa
oncogene, tumor suppressor200CXCXC (PF03128): CXCXC repeat
VEGF_C (PF14554): VEGF heparin-binding domain

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