Find Protein-Protein Interactions (PPI) Network

Choose & Enter
Choose animal: Visualization driver:
Protein/NCBI_ID(s):
Refseq_ID(s):
KEGG_KO(s):


Level of PPIs:
or Upload text file:
Update repository

Visible interactions: Visible interactors: Size of node:

Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adam9 (from a repository: Thu Apr 19 20:15:23 2018)
Examples

Layout Breadthfirst

Circle

Concentric

Cose

Grid

Random
Export graph PNG file
JPG file
JSON file

Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins1 (8.33 %)
The number (and %) of the tumor suppressors2 (16.67 %)
Total number of binary PPIs (saturation %)18 (27.27 %)
The number (and %) of affected PPIs11 (61.11 %)
PPI diameter2
PPI radius1
The average degree of PPI2.167
Assortativity coefficient-0.5654
The network average Clustering coefficient0.225
The number (and %) of a zero Clustering coefficients8 (66.67 %)
The number (and %) of a zero Betweenness Centrality10 (83.33 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Adam9
user protein, oncogene110.036105.000Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
Disintegrin (PF00200): Disintegrin
ADAM_CR (PF08516): ADAM cysteine-rich
EGF_2 (PF07974): EGF-like domain
Adam32
interactor100Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
Disintegrin (PF00200): Disintegrin
ADAM_CR (PF08516): ADAM cysteine-rich
EGF_2 (PF07974): EGF-like domain
Cd1b
interactor100MHC_I_3 (PF16497): MHC-I family domain
Ig_3 (PF13927): Immunoglobulin domain
C1-set (PF07654): Immunoglobulin C1-set domain
Insl5
interactor30.6671.000Insulin (PF00049): Insulin/IGF/Relaxin family
Itgav
tumor suppressor21.0000VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP (PF01839): FG-GAP repeat
Integrin_alpha2 (PF08441): Integrin alpha
Integrin_alpha (PF00357): Integrin alpha cytoplasmic region
Itgb5
interactor21.0000PSI_integrin (PF17205): Integrin plexin domain
Integrin_beta (PF00362): Integrin beta chain VWA domain
EGF_2 (PF07974): EGF-like domain
Integrin_B_tail (PF07965): Integrin beta tail domain
DUF2975 (PF11188): Protein of unknown function (DUF2975)
Integrin_b_cyt (PF08725): Integrin beta cytoplasmic domain
Mad2l2
interactor200HORMA (PF02301): HORMA domain
Prkcd
oncogene, tumor suppressor200C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
Pkinase (PF00069): Protein kinase domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Rnf2
interactor200zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-C4_Topoisom (PF01396): Topoisomerase DNA binding C4 zinc finger
RAWUL (PF16207): RAWUL domain RING finger- and WD40-associated ubiquitin-like
Sh3gl2
oncogene200BAR (PF03114): BAR domain
SH3_1 (PF00018): SH3 domain
Snx9
interactor200SH3_1 (PF00018): SH3 domain
PX (PF00787): PX domain
BAR_3_WASP_bdg (PF10456): WASP-binding domain of Sorting nexin protein
Vegfd
interactor100PDGF (PF00341): PDGF/VEGF domain
CXCXC (PF03128): CXCXC repeat

B a c k    t o    T o p ⇑