Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape.js taxid = 1026970 for: protein(s) Adam33 (from a repository: Tue Apr 17 09:33:57 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)35
The number (and %) of the onco-proteins1 (2.86 %)
The number (and %) of the tumor suppressors1 (2.86 %)
Total number of binary PPIs (saturation %)39 (6.55 %)
The number (and %) of affected PPIs34 (87.18 %)
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5601
The network average Clustering coefficient0.057
The number (and %) of a zero Clustering coefficients32 (91.43 %)
The number (and %) of a zero Betweenness Centrality34 (97.14 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure		 Type Number
of PPI (degree)		 Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam ID): description
Adam33

Domain structure obtained by HMM

Protein ID: XP_017656414.1 - disintegrin and metalloproteinase domain-containing protein 33
KEEG Ortholog ID: K08616
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Pep_M12B_propepPF015621402.6e-2885.200129231104232Reprolysin family propeptide
ReprolysinPF014211990.0000000006325.400262299262302Reprolysin (M12B) family zinc metalloprotease
user protein340.0021120.000Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
Adam15

Domain structure obtained by HMM

Protein ID: XP_008852635.1 - disintegrin and metalloproteinase domain-containing protein 15 isoform X1
KEEG Ortholog ID: K06836
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Pep_M12B_propepPF015621401.1e-1854.1003715323157Reprolysin family propeptide
ReprolysinPF014211992.3e-58183.500214413214416Reprolysin (M12B) family zinc metalloprotease
DisintegrinPF00200761.5e-2576.100431504431504Disintegrin
ADAM_CRPF085161134.4e-3194.000509621509628ADAM cysteine-rich
DisintegrinPF00200760.0054.000632683610684Disintegrin
CD20PF041031560.000005312.800656711614716CD20-like family
interactor100Pep_M12B_propep (PF01562): Reprolysin family propeptide
Reprolysin (PF01421): Reprolysin (M12B) family zinc metalloprotease
Disintegrin (PF00200): Disintegrin
ADAM_CR (PF08516): ADAM cysteine-rich
CD20 (PF04103): CD20-like family
Amigo1

Domain structure obtained by HMM

Protein ID: XP_008848613.1 - amphoterin-induced protein 1 isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
LRRNTPF01462280.0000878.50033593259Leucine rich repeat N-terminal domain
LRR_8PF13855617.2e-1644.1006512161121Leucine rich repeat
LRR_8PF13855611.6e-1955.800109169109169Leucine rich repeat
LRR_4PF12799430.000001115.300184222184228Leucine Rich repeats (2 copies)
LRR_1PF00560230.0650.800215226215235Leucine Rich Repeat
I-setPF07679900.0000000000429.200277357271357Immunoglobulin I-set domain
interactor200LRRNT (PF01462): Leucine rich repeat N-terminal domain
LRR_8 (PF13855): Leucine rich repeat
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
LRR_1 (PF00560): Leucine Rich Repeat
I-set (PF07679): Immunoglobulin I-set domain
Ankrd46

Domain structure obtained by HMM

Protein ID: XP_008829779.1 - ankyrin repeat domain-containing protein 46
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ank_2PF12796842.6e-1749.6001610316105Ankyrin repeats (3 copies)
Ank_4PF13637550.00000001721.2008612886129Ankyrin repeats (many copies)
interactor100Ank_2 (PF12796): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Asb7

Domain structure obtained by HMM

Protein ID: XP_008847758.1 - ankyrin repeat and SOCS box protein 7
KEEG Ortholog ID: K10329
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ank_5PF13857560.000001614.800452153Ankyrin repeats (many copies)
Ank_2PF12796841e-1854.0002010418113Ankyrin repeats (3 copies)
AnkPF00023320.00000000323.5008111580115Ankyrin repeat
Ank_2PF12796844.1e-1852.100114180105180Ankyrin repeats (3 copies)
Ank_2PF12796840.00000000001930.800185267184274Ankyrin repeats (3 copies)
SOCS_boxPF07525350.0000000000003736.000275313275313SOCS box
interactor100Ank_5 (PF13857): Ankyrin repeats (many copies)
Ank_2 (PF12796): Ankyrin repeats (3 copies)
Ank (PF00023): Ankyrin repeat
SOCS_box (PF07525): SOCS box
Atxn7

Domain structure obtained by HMM

Protein ID: XP_017650699.1 - ataxin-7
KEEG Ortholog ID: K11318
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
SCA7PF08313683.2e-3193.400192253186254SCA7, zinc-binding domain
SCA7PF08313680.0211.100618634611637SCA7, zinc-binding domain
interactor100SCA7 (PF08313): SCA7, zinc-binding domain
Clec7a

Domain structure obtained by HMM

Protein ID: XP_008845623.1 - C-type lectin domain family 7 member A isoform X3
KEEG Ortholog ID: K10074
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ly49PF083911190.0000000001727.500428340108Ly49-like protein, N-terminal region
Lectin_CPF000591081.7e-2369.800138242136242Lectin C-type domain
interactor200Ly49 (PF08391): Ly49-like protein, N-terminal region
Lectin_C (PF00059): Lectin C-type domain
Clstn1

Domain structure obtained by HMM

Protein ID: XP_008830244.1 - calsyntenin-1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
CadherinPF00028930.000000006922.4008614472145Cadherin domain
CadherinPF00028930.000000000000137.900159247159248Cadherin domain
Laminin_G_3PF133851520.00000000001730.700356475355496Concanavalin A-like lectin/glucanases superfamily
Laminin_G_2PF022101260.0000001118.800434503394536Laminin G domain
CDC45PF027246270.00000004417.900788947723968CDC45-like protein
Pox_Ag35PF032861960.0161.100909968877969Pox virus Ag35 surface protein
interactor100Cadherin (PF00028): Cadherin domain
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
Laminin_G_2 (PF02210): Laminin G domain
CDC45 (PF02724): CDC45-like protein
Pox_Ag35 (PF03286): Pox virus Ag35 surface protein
Dgcr2

Domain structure obtained by HMM

Protein ID: XP_008841216.1 - integral membrane protein DGCR2/IDD
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ldl_recept_aPF00057370.000000000000005941.60029662866Low-density lipoprotein receptor domain class A
UL45PF054732000.0000001217.700108160104177UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_CPF000591082.4e-2472.500130262129262Lectin C-type domain
Ldl_recept_aPF00057370.0191.600255269249273Low-density lipoprotein receptor domain class A
interactor100Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
UL45 (PF05473): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059): Lectin C-type domain
Dhfr

Domain structure obtained by HMM

Protein ID: XP_008851541.1 - dihydrofolate reductase
KEEG Ortholog ID: K00287
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DHFR_1PF001861614.9e-39119.8003621635216Dihydrofolate reductase
interactor100DHFR_1 (PF00186): Dihydrofolate reductase
Egfl7

Domain structure obtained by HMM

Protein ID: XP_008840191.1 - epidermal growth factor-like protein 7 isoform X1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
EMIPF07546672.6e-2265.70028942894EMI domain
EGF_2PF07974320.0000000009225.100116143110143EGF-like domain
EGF_CAPF07645429.2e-1644.200146185146185Calcium-binding EGF domain
SlyXPF04102670.0034.500210226205246SlyX
SlyXPF04102670.000966.100254277248282SlyX
EGF_2PF07974320.0331.000273280271282EGF-like domain
interactor21.0000EMI (PF07546): EMI domain
EGF_2 (PF07974): EGF-like domain
EGF_CA (PF07645): Calcium-binding EGF domain
SlyX (PF04102): SlyX
Fbxo2

Domain structure obtained by HMM

Protein ID: XP_008829808.1 - F-box only protein 2
KEEG Ortholog ID: K10099
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
F-boxPF00646480.00000000001530.30051954996F-box domain
FBAPF043001787.6e-78246.600117297117297F-box associated region
interactor100F-box (PF00646): F-box domain
FBA (PF04300): F-box associated region
Fstl1

Domain structure obtained by HMM

Protein ID: XP_008841128.1 - follistatin-related protein 1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
FOLNPF09289220.00000000006328.60029502950Follistatin/Osteonectin-like EGF domain
Kazal_2PF07648425.9e-1748.00056965696Kazal-type serine protease inhibitor domain
EF-hand_7PF13499710.0000007715.900146218143220EF-hand domain pair
Pacifastin_IPF05375400.0000000220.200241272239275Pacifastin inhibitor (LCMII)
interactor100FOLN (PF09289): Follistatin/Osteonectin-like EGF domain
Kazal_2 (PF07648): Kazal-type serine protease inhibitor domain
EF-hand_7 (PF13499): EF-hand domain pair
Pacifastin_I (PF05375): Pacifastin inhibitor (LCMII)
Galnt14

Domain structure obtained by HMM

Protein ID: XP_008849185.1 - polypeptide N-acetylgalactosaminyltransferase 14 isoform X1
KEEG Ortholog ID: K00710
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
DUF4519PF15012560.0000549.700729230Domain of unknown function (DUF4519)
Glycos_transf_2PF005351702.4e-3298.300114283114293Glycosyl transferase family 2
Glyco_transf_7CPF02709780.0000007115.200280333272340N-terminal domain of galactosyltransferase
Ricin_B_lectinPF006521278.9e-2573.600422547420547Ricin-type beta-trefoil lectin domain
interactor100DUF4519 (PF15012): Domain of unknown function (DUF4519)
Glycos_transf_2 (PF00535): Glycosyl transferase family 2
Glyco_transf_7C (PF02709): N-terminal domain of galactosyltransferase
Ricin_B_lectin (PF00652): Ricin-type beta-trefoil lectin domain
Hmox1

Domain structure obtained by HMM

Protein ID: XP_008841313.1 - heme oxygenase 1
KEEG Ortholog ID: K00510
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Heme_oxygenasePF011262051.2e-85272.5001221611216Heme oxygenase
interactor200Heme_oxygenase (PF01126): Heme oxygenase
Itgb5

Domain structure obtained by HMM

Protein ID: XP_008841196.1 - integrin beta-5 isoform X1
KEEG Ortholog ID: K06588
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
PSI_integrinPF17205488.4e-1850.30026752676Integrin plexin domain
Integrin_betaPF003622482.8e-111357.200134382133382Integrin beta chain VWA domain
EGF_2PF07974320.000005213.100473498465498EGF-like domain
EGF_2PF07974320.000004213.400513548513552EGF-like domain
EGF_2PF07974320.0000001817.800555585555585EGF-like domain
EGF_2PF07974320.00000001421.300594625594625EGF-like domain
Integrin_B_tailPF07965854.2e-2264.800635719635719Integrin beta tail domain
DUF2975PF111881310.000002913.400701755691763Protein of unknown function (DUF2975)
Integrin_b_cytPF08725458.2e-2263.000743788743788Integrin beta cytoplasmic domain
interactor100PSI_integrin (PF17205): Integrin plexin domain
Integrin_beta (PF00362): Integrin beta chain VWA domain
EGF_2 (PF07974): EGF-like domain
Integrin_B_tail (PF07965): Integrin beta tail domain
DUF2975 (PF11188): Protein of unknown function (DUF2975)
Integrin_b_cyt (PF08725): Integrin beta cytoplasmic domain
Kcnj8

Domain structure obtained by HMM

Protein ID: XP_008849821.1 - ATP-sensitive inward rectifier potassium channel 8
KEEG Ortholog ID: K05001
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
IRKPF010073305.8e-143461.8003736837371Inward rectifier potassium channel
interactor100IRK (PF01007): Inward rectifier potassium channel
LOC103738938

Domain structure obtained by HMM

Protein ID: XP_008837361.1 - S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
KEEG Ortholog ID: K15449
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Flavodoxin_1PF002581434.6e-2987.7007921579230Flavodoxin
DUF4769PF159922570.000008311.800229327219353Domain of unknown function (DUF4769)
Radical_SAMPF040551671.6e-3299.400399580398580Radical SAM superfamily
Wyosine_formPF08608631.6e-3194.800583645582645Wyosine base formation
interactor100Flavodoxin_1 (PF00258): Flavodoxin
DUF4769 (PF15992): Domain of unknown function (DUF4769)
Radical_SAM (PF04055): Radical SAM superfamily
Wyosine_form (PF08608): Wyosine base formation
Lrp12

Domain structure obtained by HMM

Protein ID: XP_008849737.1 - low-density lipoprotein receptor-related protein 12
KEEG Ortholog ID: K20050
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
CUBPF004311104.2e-3090.6004715647156CUB domain
Ldl_recept_aPF00057370.00000000000005638.400165200164200Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.000000000128.000214254213254Low-density lipoprotein receptor domain class A
CUBPF004311101.6e-2369.400259369259369CUB domain
Ldl_recept_aPF00057370.0000005116.200375410373410Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.0000000001227.800412448411448Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.000000000000001743.300451485450485Low-density lipoprotein receptor domain class A
interactor100CUB (PF00431): CUB domain
Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
Lrp5

Domain structure obtained by HMM

Protein ID: XP_008844525.1 - low-density lipoprotein receptor-related protein 5 isoform X1
KEEG Ortholog ID: K03068
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ldl_recept_bPF00058424.9e-1851.700139140Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.000000001624.40043814381Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00002411.100859984120Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670362.7e-1646.000135172135172Coagulation Factor Xa inhibitory site
Ldl_recept_bPF00058420.00000000007528.700221261221261Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058421.1e-1647.400264304264304Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058422.4e-1646.300307347307348Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.0000000002527.000351381351388Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.0000779.500393407392424Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670360.00000000000006938.200441476441476Coagulation Factor Xa inhibitory site
Ldl_recept_bPF00058420.00000000001331.100523563523563Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.000000000002833.300567606566606Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000001321.500609649609649Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.000000009522.000652688652688Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000001721.100692723692732Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670360.0000000000004435.700742777742777Coagulation Factor Xa inhibitory site
Ldl_recept_bPF00058420.00185.100826844825854Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.000337.500873910872910Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000001921.000915956915957Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000000224.100960998960998Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00047.2001001103710011037Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670360.000000000009731.4001053108910531089Coagulation Factor Xa inhibitory site
Ldl_recept_aPF00057375.9e-1644.8001094113110931131Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.000000000000002542.8001134116811321168Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.00000000000001140.8001172120611701206Low-density lipoprotein receptor domain class A
oncogene100Ldl_recept_b (PF00058): Low-density lipoprotein receptor repeat class B
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
Lrp6

Domain structure obtained by HMM

Protein ID: XP_008835834.1 - low-density lipoprotein receptor-related protein 6 isoform X1
KEEG Ortholog ID: K03068
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ldl_recept_bPF00058420.0000002617.4006310463104Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000000000000144.300107147107147Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058421.1e-1647.400150191150191Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000000004429.500194233194234Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00002511.000236248235256Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670360.000000000000003642.300286323286323Coagulation Factor Xa inhibitory site
Ldl_recept_bPF00058420.000000000000001244.000415455415455Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058426.3e-1748.200458499458499Low-density lipoprotein receptor repeat class B
SGLPF084502460.0000001517.300476526457534SMP-30/Gluconolaconase/LRE-like region
Ldl_recept_bPF00058420.000089.400543569543580Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670362.9e-1645.800592627592627Coagulation Factor Xa inhibitory site
Ldl_recept_bPF00058420.0000000002127.300674714674714Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.0000000000002736.500718757717757Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.000000000009631.600760800760800Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000005619.500803839803839Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000003820.100843874843883Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670360.00000000000000442.200893929893929Coagulation Factor Xa inhibitory site
Ldl_recept_bPF00058420.0000649.7009799989771009Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00004910.1001026106410261066Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.000000000725.6001069111010691111Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.0000000008225.4001114115311141154Low-density lipoprotein receptor repeat class B
Ldl_recept_bPF00058420.00000513.3001157118311551191Low-density lipoprotein receptor repeat class B
FXa_inhibitionPF14670360.000000000001733.8001207124312071243Coagulation Factor Xa inhibitory site
Ldl_recept_aPF00057370.000000000000003342.4001248128512471285Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.000000000000005341.7001288132212861322Low-density lipoprotein receptor domain class A
Ldl_recept_aPF00057370.0000000000003336.0001326136013241360Low-density lipoprotein receptor domain class A
interactor100Ldl_recept_b (PF00058): Low-density lipoprotein receptor repeat class B
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
SGL (PF08450): SMP-30/Gluconolaconase/LRE-like region
Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
Lsr

Domain structure obtained by HMM

Protein ID: XP_008826229.1 - lipolysis-stimulated lipoprotein receptor isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
V-setPF076861090.0330.70052664577Immunoglobulin V-set domain
V-setPF076861090.00000009818.400127173108186Immunoglobulin V-set domain
LSRPF05624481.6e-2575.200187234187234Lipolysis stimulated receptor (LSR)
interactor100V-set (PF07686): Immunoglobulin V-set domain
LSR (PF05624): Lipolysis stimulated receptor (LSR)
Maneal

Domain structure obtained by HMM

Protein ID: XP_008848436.1 - glycoprotein endo-alpha-1,2-mannosidase-like protein
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Glyco_hydro_99PF163173427.6e-102327.0002322716228Glycosyl hydrolase family 99
interactor100Glyco_hydro_99 (PF16317): Glycosyl hydrolase family 99
Neto2

Domain structure obtained by HMM

Protein ID: XP_008827859.1 - neuropilin and tolloid-like protein 2 isoform X5
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
CUBPF004311100.00000002120.80050815083CUB domain
CUBPF004311100.000000000725.5008312080120CUB domain
CUBPF004311100.00000000000001240.900167250141253CUB domain
Ldl_recept_aPF00057370.00000000003329.600260295259295Low-density lipoprotein receptor domain class A
CUBPF004311100.0112.300385428368442CUB domain
interactor100CUB (PF00431): CUB domain
Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
Notch3

Domain structure obtained by HMM

Protein ID: XP_008828211.1 - neurogenic locus notch homolog protein 3
KEEG Ortholog ID: K20995
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
EGFPF00008320.0000000719.00045774577EGF-like domain
EGFPF00008320.0000002417.3008411784118EGF-like domain
EGFPF00008320.000000003623.100125155125156EGF-like domain
EGF_CAPF07645420.000000000007131.700160192160203Calcium-binding EGF domain
EGFPF00008320.000000004522.800203233203234EGF-like domain
EGFPF00008320.00000000007228.600242271242272EGF-like domain
EGF_CAPF07645420.0000000000006935.000276309276317Calcium-binding EGF domain
EGFPF00008320.000000009221.800320348319350EGF-like domain
EGFPF00008320.000000002423.700357387357387EGF-like domain
cEGFPF12662240.0000389.900379396378396Complement Clr-like EGF-like
EGF_CAPF07645420.0000000000001237.400393426393432Calcium-binding EGF domain
cEGFPF12662240.000366.800416436416436Complement Clr-like EGF-like
EGF_CAPF07645420.000000001424.400433464433469Calcium-binding EGF domain
cEGFPF12662240.0000419.800455474454474Complement Clr-like EGF-like
EGFPF00008320.0000000006825.500475505475505EGF-like domain
EGFPF00008320.000000000002233.400513541513543EGF-like domain
EGFPF00008320.0000000000230.400551580551580EGF-like domain
EGFPF00008320.0000000001427.700588617588618EGF-like domain
EGFPF00008320.0000001218.300626654626655EGF-like domain
hEGFPF12661220.000000003523.500668689668689Human growth factor-like EGF
EGFPF00008320.00000002720.400701730699730EGF-like domain
EGFPF00008320.000000008222.000740769740770EGF-like domain
EGFPF00008320.0000001917.700777808777808EGF-like domain
EGF_CAPF07645420.00000000001530.700812844812850Calcium-binding EGF domain
EGFPF00008320.000000000006631.900855885855885EGF-like domain
hEGFPF12661220.000000005522.900898918898918Human growth factor-like EGF
cEGFPF12662240.000386.700909928909943Complement Clr-like EGF-like
EGFPF00008320.0000000003626.400930959930960EGF-like domain
EGFPF00008320.000000001924.100968997968998EGF-like domain
EGF_alliinasePF04863550.0211.50098710069781006Alliinase EGF-like domain
EGFPF00008320.00000000124.9001006103410061034EGF-like domain
EGFPF00008320.00000006819.1001057108210521082EGF-like domain
EGFPF00008320.00000000005329.0001090111910901120EGF-like domain
EGFPF00008320.00000000007528.5001128115311281157EGF-like domain
EGFPF00008320.00000000001231.1001176120011661201EGF-like domain
cEGFPF12662240.0000004816.0001188120811881208Complement Clr-like EGF-like
EGF_CAPF07645420.00000812.4001205124112051255Calcium-binding EGF domain
EGFPF00008320.0000001418.0001250128412501285EGF-like domain
EGF_alliinasePF04863550.0112.5001274129312681293Alliinase EGF-like domain
EGFPF00008320.000427.0001304132212931323EGF-like domain
cEGFPF12662240.00373.6001312132913101340Complement Clr-like EGF-like
EGFPF00008320.0000000001128.0001339137113391371EGF-like domain
NotchPF00066360.0000000000000141.0001385141813841418LNR domain
NotchPF00066360.00000000000001840.3001425145814251459LNR domain
NotchPF00066360.000000000000001543.7001466150014641501LNR domain
NODPF06816562.1e-2471.2001505155915051560NOTCH protein
NODPPF07684591.1e-2575.9001575163415751635NOTCH protein
Ank_5PF13857560.000586.6001775179617731802Ankyrin repeats (many copies)
AnkPF00023320.00000001721.1001786183317861834Ankyrin repeat
Ank_2PF12796840.000000000000336.5001818189718111901Ankyrin repeats (3 copies)
Ank_2PF12796840.000000000000735.4001883196718781967Ankyrin repeats (3 copies)
Ank_2PF12796841.7e-1646.9001908199719082001Ankyrin repeats (3 copies)
Ank_2PF12796840.00000001821.2001957202219562024Ankyrin repeats (3 copies)
DUF3454PF11936642.1e-2059.3002212226922062269Domain of unknown function (DUF3454)
oncogene, tumor suppressor21.0000EGF (PF00008): EGF-like domain
EGF_CA (PF07645): Calcium-binding EGF domain
cEGF (PF12662): Complement Clr-like EGF-like
hEGF (PF12661): Human growth factor-like EGF
EGF_alliinase (PF04863): Alliinase EGF-like domain
Notch (PF00066): LNR domain
NOD (PF06816): NOTCH protein
NODP (PF07684): NOTCH protein
Ank_5 (PF13857): Ankyrin repeats (many copies)
Ank (PF00023): Ankyrin repeat
Ank_2 (PF12796): Ankyrin repeats (3 copies)
DUF3454 (PF11936): Domain of unknown function (DUF3454)
Pdf

Domain structure obtained by HMM

Protein ID: XP_008832350.1 - peptide deformylase, mitochondrial
KEEG Ortholog ID: K01462
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Pep_deformylasePF013271594.2e-45139.4005421852221Polypeptide deformylase
interactor100Pep_deformylase (PF01327): Polypeptide deformylase
Sdf2l1

Domain structure obtained by HMM

Protein ID: XP_008840448.1 - stromal cell-derived factor 2-like protein 1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
MIRPF028151860.000000000000002742.8004917647178MIR domain
MIRPF028151860.000138.000152186146210MIR domain
interactor100MIR (PF02815): MIR domain
Slc27a3

Domain structure obtained by HMM

Protein ID: XP_008853510.1 - long-chain fatty acid transport protein 3
KEEG Ortholog ID: K08772
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
AMP-bindingPF005014230.0000967.1007410971116AMP-binding enzyme
AMP-bindingPF005014231.5e-64204.200154539150540AMP-binding enzyme
AMP-binding_CPF13193740.0000000006426.200548624548624AMP-binding enzyme C-terminal domain
interactor100AMP-binding (PF00501): AMP-binding enzyme
AMP-binding_C (PF13193): AMP-binding enzyme C-terminal domain
Slc30a2

Domain structure obtained by HMM

Protein ID: XP_008835020.1 - zinc transporter 2
KEEG Ortholog ID: K14689
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Cation_effluxPF015451998.3e-51158.7006426664266Cation efflux family
interactor100Cation_efflux (PF01545): Cation efflux family
Tmbim6

Domain structure obtained by HMM

Protein ID: XP_008846973.1 - bax inhibitor 1
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Bax1-IPF010272072.2e-46144.4002422524225Inhibitor of apoptosis-promoting Bax1
interactor100Bax1-I (PF01027): Inhibitor of apoptosis-promoting Bax1
Tmem39b

Domain structure obtained by HMM

Protein ID: XP_017657482.1 - transmembrane protein 39B isoform X4
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Tmp39PF102714314.3e-161522.70023511351Putative transmembrane protein
interactor100Tmp39 (PF10271): Putative transmembrane protein
Tmem67

Domain structure obtained by HMM

Protein ID: XP_008846047.1 - meckelin isoform X1
KEEG Ortholog ID: K19348
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Ephrin_rec_likePF07699480.00174.40048764479Putative ephrin-receptor like
NCD3GPF07562510.0000559.4008012076123Nine Cysteines Domain of family 3 GPCR
Tme5_EGF_likePF09064340.000003913.000124140115141Thrombomodulin like fifth domain, EGF-like
C1_1PF00130530.0121.900143174136188Phorbol esters/diacylglycerol binding domain (C1 domain)
MeckelinPF0977382401161.800168992167992Meckelin (Transmembrane protein 67)
interactor100Ephrin_rec_like (PF07699): Putative ephrin-receptor like
NCD3G (PF07562): Nine Cysteines Domain of family 3 GPCR
Tme5_EGF_like (PF09064): Thrombomodulin like fifth domain, EGF-like
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
Meckelin (PF09773): Meckelin (Transmembrane protein 67)
Ttc17

Domain structure obtained by HMM

Protein ID: XP_008847151.1 - tetratricopeptide repeat protein 17 isoform X2
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
TPR_17PF13431340.0580.500224235219242Tetratricopeptide repeat
TPR_12PF13424770.0450.400261274223283Tetratricopeptide repeat
TPR_17PF13431340.00344.300291308286332Tetratricopeptide repeat
TPR_8PF13181340.00813.000298316296318Tetratricopeptide repeat
TPR_2PF07719340.000158.300604633602634Tetratricopeptide repeat
TPR_1PF00515340.00000002120.100675701672701Tetratricopeptide repeat
TPR_7PF13176360.000003813.2001056108810551089Tetratricopeptide repeat
ChAPsPF092953950.0000004415.2001068114810331163ChAPs (Chs5p-Arf1p-binding proteins)
TPR_1PF00515340.00000000223.4001127115711251157Tetratricopeptide repeat
interactor100TPR_17 (PF13431): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_8 (PF13181): Tetratricopeptide repeat
TPR_2 (PF07719): Tetratricopeptide repeat
TPR_1 (PF00515): Tetratricopeptide repeat
TPR_7 (PF13176): Tetratricopeptide repeat
ChAPs (PF09295): ChAPs (Chs5p-Arf1p-binding proteins)
Ubqln4

Domain structure obtained by HMM

Protein ID: XP_008852048.1 - ubiquilin-4
KEEG Ortholog ID: K04523
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
ubiquitinPF00240724.6e-1954.30015841585Ubiquitin family
DUF1180PF066791690.000576.5008314372164Protein of unknown function (DUF1180)
Fur_reg_FbpBPF13040390.000386.300176198174200Fur-regulated basic protein B
partial_CstFPF15861620.000925.300200223190228Partial cleavage stimulation factor domain
XPC-bindingPF09280570.000556.000212241203249XPC-binding domain
CRFPF00473380.00115.500242259238270Corticotropin-releasing factor family
XPC-bindingPF09280570.00313.600251265239272XPC-binding domain
DUF1180PF066791690.0490.200316385305402Protein of unknown function (DUF1180)
XPC-bindingPF09280570.00001910.700378400375402XPC-binding domain
Arm_2PF048262540.000006911.800385461379480Armadillo-like
XPC-bindingPF09280570.0210.900459470456486XPC-binding domain
UBAPF00627370.00000000001230.700559594557594UBA/TS-N domain
interactor200ubiquitin (PF00240): Ubiquitin family
DUF1180 (PF06679): Protein of unknown function (DUF1180)
Fur_reg_FbpB (PF13040): Fur-regulated basic protein B
partial_CstF (PF15861): Partial cleavage stimulation factor domain
XPC-binding (PF09280): XPC-binding domain
CRF (PF00473): Corticotropin-releasing factor family
Arm_2 (PF04826): Armadillo-like
UBA (PF00627): UBA/TS-N domain
Zdhhc6

Domain structure obtained by HMM

Protein ID: XP_008828389.1 - palmitoyltransferase ZDHHC6 isoform X1
KEEG Ortholog ID: K20031
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
zf-DHHCPF015291341.4e-40124.7009724394244DHHC palmitoyltransferase
SH3_2PF07653555e-1644.500317396317396Variant SH3 domain
interactor100zf-DHHC (PF01529): DHHC palmitoyltransferase
SH3_2 (PF07653): Variant SH3 domain

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