Find Protein-Protein Interactions (PPI) Network

Choose & Enter
Choose animal: Visualization driver:
Protein/NCBI_ID(s):
Refseq_ID(s):
KEGG_KO(s):


Level of PPIs:
or Upload text file:
Update repository

Visible interactions: Visible interactors: Size of node:

Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acp5 (from a repository: Fri Apr 13 12:06:14 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)22
The number (and %) of the onco-proteins4 (18.18 %)
The number (and %) of the tumor suppressors6 (27.27 %)
Total number of binary PPIs (saturation %)38 (16.45 %)
The number (and %) of affected PPIs22 (57.89 %)
PPI diameter2
PPI radius1
The average degree of PPI2.909
Assortativity coefficient-0.5867
The network average Clustering coefficient0.287
The number (and %) of a zero Clustering coefficients13 (59.09 %)
The number (and %) of a zero Betweenness Centrality16 (72.73 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acp5
user protein220.052387.000Metallophos (PF00149): Calcineurin-like phosphoesterase
Calr
oncogene50.8330.667Calreticulin (PF00262): Calreticulin family
RNA_pol_Rpc4 (PF05132): RNA polymerase III RPC4
Canx
interactor50.6003.333TRAP_alpha (PF03896): Translocon-associated protein (TRAP), alpha subunit
Calreticulin (PF00262): Calreticulin family
DUF1510 (PF07423): Protein of unknown function (DUF1510)
Ciz1
tumor suppressor100SLC12 (PF03522): Solute carrier family 12
Piezo_RRas_bdg (PF12166): Piezo non-specific cation channel, R-Ras-binding domain
DivIC (PF04977): Septum formation initiator
zf-C2H2_jaz (PF12171): Zinc-finger double-stranded RNA-binding
FOXP-CC (PF16159): FOXP coiled-coil domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-U1 (PF06220): U1 zinc finger
Rubredoxin (PF00301): Rubredoxin
Clgn
interactor100Calreticulin (PF00262): Calreticulin family
SieB (PF14163): Super-infection exclusion protein B
APG6 (PF04111): Autophagy protein Apg6
Egr2
tumor suppressor100DUF3446 (PF11928): Domain of unknown function (DUF3446)
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
Ganab
tumor suppressor31.0000DUF5110 (PF17137): Domain of unknown function (DUF5110)
Gal_mutarotas_2 (PF13802): Galactose mutarotase-like
Glyco_hydro_31 (PF01055): Glycosyl hydrolases family 31
Hsd17b7
interactor100adh_short (PF00106): short chain dehydrogenase
Hspa5
heat shock, oncogene60.5004.667HSP70 (PF00012): Hsp70 protein
Klhl15
interactor200BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Kelch_6 (PF13964): Kelch motif
Kelch_1 (PF01344): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
LOC103730245
interactor100Sel1 (PF08238): Sel1 repeat
Mapk9
oncogene, tumor suppressor200Pkinase (PF00069): Protein kinase domain
CcdA (PF07362): Post-segregation antitoxin CcdA
Kinase-like (PF14531): Kinase-like
Ngly1
interactor100PUB (PF09409): PUB domain
Transglut_core (PF01841): Transglutaminase-like superfamily
Rad4 (PF03835): Rad4 transglutaminase-like domain
PAW (PF04721): PNGase C-terminal domain, mannose-binding module PAW
Os9
interactor41.0000PRKCSH (PF07915): Glucosidase II beta subunit-like protein
PRKCSH_1 (PF13015): Glucosidase II beta subunit-like protein
FYDLN_acid (PF09538): Protein of unknown function (FYDLN_acid)
Cwf_Cwc_15 (PF04889): Cwf15/Cwc15 cell cycle control protein
RRN3 (PF05327): RNA polymerase I specific transcription initiation factor RRN3
DUF4666 (PF15697): Domain of unknown function (DUF4666)
Pdcd5
tumor suppressor100EF-1_beta_acid (PF10587): Eukaryotic elongation factor 1 beta central acidic region
dsDNA_bind (PF01984): Double-stranded DNA-binding domain
Pdia3
interactor40.6671.667Thioredoxin (PF00085): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
Ppp2cb
tumor suppressor100STPPase_N (PF16891): Serine-threonine protein phosphatase N-terminal domain
Metallophos (PF00149): Calcineurin-like phosphoesterase
Rpa2
oncogene30.6670.667tRNA_anti-codon (PF01336): OB-fold nucleic acid binding domain
RMI2 (PF16100): RecQ-mediated genome instability protein 2
RPA_C (PF08784): Replication protein A C terminal
Sel1l
oncogene31.0000fn2 (PF00040): Fibronectin type II domain
Sel1 (PF08238): Sel1 repeat
TPR_2 (PF07719): Tetratricopeptide repeat
TPR_1 (PF00515): Tetratricopeptide repeat
Selenof
interactor100Sep15_SelM (PF08806): Sep15/SelM redox domain
Slc35f6
interactor100SLC35F (PF06027): Solute carrier family 35
EamA (PF00892): EamA-like transporter family
Uggt1
interactor100UDP-g_GGTase (PF06427): UDP-glucose:Glycoprotein Glucosyltransferase
Glyco_transf_8 (PF01501): Glycosyl transferase family 8

B a c k    t o    T o p ⇑