Find Protein-Protein Interactions (PPI) Network

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Protein/NCBI_ID(s): Refseq_ID(s): KEGG_KO(s):	Acp1
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Visible interactions:

Visible interactors:

Size of node:

Visualization interactions

Cytoscape Web taxid = 1026970 for: protein(s) Acp1 (from a repository: Wed Apr 11 08:12:38 2018)

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Statistics and Network structure information

Statistics of PPI	Value(s)
The number of interactors (fusion and proteins)	33
The number (and %) of the onco-proteins	7 (21.21 %)
The number (and %) of the tumor suppressors	4 (12.12 %)
Total number of binary PPIs (saturation %)	91 (17.23 %)
The number (and %) of affected PPIs	33 (36.26 %)
PPI diameter	2
PPI radius	1
The average degree of PPI	4.606
Assortativity coefficient	-0.5081
The network average Clustering coefficient	0.419
The number (and %) of a zero Clustering coefficients	11 (33.33 %)
The number (and %) of a zero Betweenness Centrality	16 (48.48 %)

ACTIVE INTERACTORS

List of active interactors

Interactor,
Domain structure

Type

Number
of PPI (degree)

Clustering
Coefficient

Betweenness
Centrality

Domains (Pfam ID): description

Acp1

XP_008833623.1

Domain structure obtained by HMM

Protein ID: XP_008833623.1 - low molecular weight phosphotyrosine protein phosphatase isoform X1
KEEG Ortholog ID: K14394

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
LMWPc	PF01451	142	3.7e-47	146.500	9	166	9	166	Low molecular weight phosphotyrosine protein phosphatase

user protein

0.089

803.600

LMWPc (PF01451): Low molecular weight phosphotyrosine protein phosphatase

Abracl

XP_008820248.1

Domain structure obtained by HMM

Protein ID: XP_008820248.1 - costars family protein ABRACL

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Costars	PF14705	76	4.3e-34	102.900	3	79	2	79	Costars

interactor

Costars (PF14705): Costars

Actb

XP_008849594.1

Domain structure obtained by HMM

Protein ID: XP_008849594.1 - actin, cytoplasmic 1
KEEG Ortholog ID: K05692

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Actin	PF00022	407	2.3e-155	503.200	3	375	2	375	Actin

oncogene

0.429

7.833

Actin (PF00022): Actin

Actbl2

XP_008830814.1

Domain structure obtained by HMM

Protein ID: XP_008830814.1 - beta-actin-like protein 2 isoform X1

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Actin	PF00022	407	8.1e-151	488.200	4	376	3	376	Actin

interactor

0.667

1.067

Actin (PF00022): Actin

Ada

XP_008849240.1

Domain structure obtained by HMM

Protein ID: XP_008849240.1 - adenosine deaminase
KEEG Ortholog ID: K01488

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
A_deaminase	PF00962	328	4.1e-110	354.200	9	345	8	346	Adenosine/AMP deaminase

interactor

0.667

1.067

A_deaminase (PF00962): Adenosine/AMP deaminase

Cops5

XP_008852994.1

Domain structure obtained by HMM

Protein ID: XP_008852994.1 - COP9 signalosome complex subunit 5 isoform X1
KEEG Ortholog ID: K09613

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
JAB	PF01398	118	4.8e-38	116.100	53	163	50	164	JAB1/Mov34/MPN/PAD-1 ubiquitin protease

interactor

0.286

10.800

JAB (PF01398): JAB1/Mov34/MPN/PAD-1 ubiquitin protease

Ctnnb1

XP_008847656.1

Domain structure obtained by HMM

Protein ID: XP_008847656.1 - catenin beta-1
KEEG Ortholog ID: K02105

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Arm	PF00514	41	0.00000000037	26.000	229	262	224	263	Armadillo/beta-catenin-like repeat
Arm	PF00514	41	0.014	1.900	272	303	267	306	Armadillo/beta-catenin-like repeat
Arm	PF00514	41	0.0000000000052	31.800	351	389	350	390	Armadillo/beta-catenin-like repeat
Arm	PF00514	41	0.0000016	14.400	400	428	397	429	Armadillo/beta-catenin-like repeat
Arm	PF00514	41	0.0000000032	23.000	433	473	431	473	Armadillo/beta-catenin-like repeat
Atx10homo_assoc	PF09759	99	0.053	0.000	479	517	476	529	Spinocerebellar ataxia type 10 protein domain
HEAT_EZ	PF13513	55	0.022	1.600	518	541	511	553	HEAT-like repeat
Arm	PF00514	41	0.000072	9.200	527	546	521	550	Armadillo/beta-catenin-like repeat
Arm	PF00514	41	0.00000000046	25.700	584	622	583	623	Armadillo/beta-catenin-like repeat
DUF3361	PF11841	154	0.0001	8.500	608	684	594	688	Domain of unknown function (DUF3361)

oncogene

0.500

1.733

Arm (PF00514): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
DUF3361 (PF11841): Domain of unknown function (DUF3361)

Dnajc13

XP_008823308.1

Domain structure obtained by HMM

Protein ID: XP_008823308.1 - dnaJ homolog subfamily C member 13 isoform X1
KEEG Ortholog ID: K09533

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Adaptin_N	PF01602	524	0.0049	1.400	455	494	432	544	Adaptin N terminal region
Adaptin_N	PF01602	524	0.0061	1.100	861	937	843	938	Adaptin N terminal region
Arm	PF00514	41	0.00079	5.900	930	952	928	957	Armadillo/beta-catenin-like repeat
DUF4339	PF14237	44	2.1e-18	52.200	981	1025	981	1025	Domain of unknown function (DUF4339)
DnaJ	PF00226	63	5.5e-19	54.400	1306	1363	1306	1365	DnaJ domain
Arm_2	PF04826	254	0.00015	7.400	1778	1842	1775	1886	Armadillo-like
Adaptin_N	PF01602	524	0.00045	4.900	1813	1872	1756	1895	Adaptin N terminal region
Arm_2	PF04826	254	0.0027	3.300	2012	2085	2005	2094	Armadillo-like
Adaptin_N	PF01602	524	0.0016	3.100	2056	2129	1994	2141	Adaptin N terminal region

interactor

Adaptin_N (PF01602): Adaptin N terminal region
Arm (PF00514): Armadillo/beta-catenin-like repeat
DUF4339 (PF14237): Domain of unknown function (DUF4339)
DnaJ (PF00226): DnaJ domain
Arm_2 (PF04826): Armadillo-like

Dusp1

XP_008848991.1

Domain structure obtained by HMM

Protein ID: XP_008848991.1 - dual specificity protein phosphatase 1
KEEG Ortholog ID: K21278

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Rhodanese	PF00581	107	0.00000000000027	36.700	19	130	10	131	Rhodanese-like domain
DSPc	PF00782	133	2e-52	162.800	181	310	181	311	Dual specificity phosphatase, catalytic domain

tumor suppressor

Rhodanese (PF00581): Rhodanese-like domain
DSPc (PF00782): Dual specificity phosphatase, catalytic domain

Dusp12

XP_008847289.1

Domain structure obtained by HMM

Protein ID: XP_008847289.1 - dual specificity protein phosphatase 12
KEEG Ortholog ID: K14819

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
DSPc	PF00782	133	7.9e-30	89.600	34	165	34	167	Dual specificity phosphatase, catalytic domain
Yippee-Mis18	PF03226	105	0.000012	11.700	217	298	216	305	Yippee zinc-binding/DNA-binding /Mis18, centromere assembly

interactor

DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Yippee-Mis18 (PF03226): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly

Dusp2

XP_008836380.1

Domain structure obtained by HMM

Protein ID: XP_008836380.1 - dual specificity protein phosphatase 2
KEEG Ortholog ID: K04459

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Rhodanese	PF00581	107	0.0000000000013	34.500	22	141	19	142	Rhodanese-like domain
DSPc	PF00782	133	6.9e-48	148.100	184	314	184	314	Dual specificity phosphatase, catalytic domain

oncogene

Rhodanese (PF00581): Rhodanese-like domain
DSPc (PF00782): Dual specificity phosphatase, catalytic domain

Dusp28

XP_008827398.1

Domain structure obtained by HMM

Protein ID: XP_008827398.1 - dual specificity phosphatase 28
KEEG Ortholog ID: K14165

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
OGFr_III	PF04680	20	0.07	0.300	11	17	9	25	Opioid growth factor receptor repeat
DSPc	PF00782	133	1.9e-32	98.100	26	155	26	156	Dual specificity phosphatase, catalytic domain
OGFr_III	PF04680	20	0.063	0.500	154	161	154	168	Opioid growth factor receptor repeat

interactor

OGFr_III (PF04680): Opioid growth factor receptor repeat
DSPc (PF00782): Dual specificity phosphatase, catalytic domain

Epha2

XP_017650976.1

Domain structure obtained by HMM

Protein ID: XP_017650976.1 - ephrin type-A receptor 2
KEEG Ortholog ID: K05103

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Ephrin_lbd	PF01404	178	3.5e-65	205.500	3	165	1	165	Ephrin receptor ligand binding domain
Laminin_EGF	PF00053	49	0.00009	8.900	220	254	194	257	Laminin EGF domain
Ephrin_rec_like	PF07699	48	0.0000000021	23.400	234	270	229	273	Putative ephrin-receptor like
Ephrin_rec_like	PF07699	48	0.04	0.100	266	291	264	307	Putative ephrin-receptor like
fn3	PF00041	85	4.8e-18	51.700	294	383	294	388	Fibronectin type III domain
DUF2369	PF10179	95	0.00002	11.300	357	419	356	435	Uncharacterised conserved protein (DUF2369)
fn3	PF00041	85	1e-20	60.200	402	483	401	483	Fibronectin type III domain
EphA2_TM	PF14575	77	6.7e-25	74.100	501	574	501	574	Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr	PF07714	260	2.5e-104	334.300	579	836	577	836	Protein tyrosine kinase
SAM_1	PF00536	64	7.4e-26	76.800	869	931	867	931	SAM domain (Sterile alpha motif)

oncogene, tumor suppressor

1.000

Ephrin_lbd (PF01404): Ephrin receptor ligand binding domain
Laminin_EGF (PF00053): Laminin EGF domain
Ephrin_rec_like (PF07699): Putative ephrin-receptor like
fn3 (PF00041): Fibronectin type III domain
DUF2369 (PF10179): Uncharacterised conserved protein (DUF2369)
EphA2_TM (PF14575): Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
SAM_1 (PF00536): SAM domain (Sterile alpha motif)

Ephb1

XP_008846767.1

Domain structure obtained by HMM

Protein ID: XP_008846767.1 - ephrin type-B receptor 1
KEEG Ortholog ID: K05110

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Ephrin_lbd	PF01404	178	5.9e-76	240.600	20	196	20	196	Ephrin receptor ligand binding domain
EGF_2	PF07974	32	0.000029	10.700	238	260	233	263	EGF-like domain
Ephrin_rec_like	PF07699	48	0.000000023	20.100	260	298	258	303	Putative ephrin-receptor like
cEGF	PF12662	24	0.0011	5.300	300	308	298	320	Complement Clr-like EGF-like
fn3	PF00041	85	9.5e-17	47.500	326	413	324	418	Fibronectin type III domain
fn3	PF00041	85	2.8e-19	55.600	442	518	433	518	Fibronectin type III domain
EphA2_TM	PF14575	77	2.5e-26	78.600	542	615	542	616	Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr	PF07714	260	3.6e-103	330.400	620	878	619	878	Protein tyrosine kinase
SAM_1	PF00536	64	2.6e-24	71.800	912	972	909	973	SAM domain (Sterile alpha motif)

interactor

Ephrin_lbd (PF01404): Ephrin receptor ligand binding domain
EGF_2 (PF07974): EGF-like domain
Ephrin_rec_like (PF07699): Putative ephrin-receptor like
cEGF (PF12662): Complement Clr-like EGF-like
fn3 (PF00041): Fibronectin type III domain
EphA2_TM (PF14575): Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
SAM_1 (PF00536): SAM domain (Sterile alpha motif)

Ephb2

XP_008846790.1

Domain structure obtained by HMM

Protein ID: XP_008846790.1 - ephrin type-B receptor 2 isoform X1
KEEG Ortholog ID: K05111

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Ephrin_lbd	PF01404	178	2e-76	242.100	1	174	1	174	Ephrin receptor ligand binding domain
EGF_2	PF07974	32	0.000023	11.000	216	238	211	246	EGF-like domain
cEGF	PF12662	24	0.000044	9.700	230	247	230	247	Complement Clr-like EGF-like
Ephrin_rec_like	PF07699	48	0.000000000035	29.100	245	279	238	282	Putative ephrin-receptor like
EGF_2	PF07974	32	0.0073	3.000	276	287	255	290	EGF-like domain
fn3	PF00041	85	2.8e-21	62.000	303	398	303	398	Fibronectin type III domain
fn3	PF00041	85	3.6e-20	58.400	415	497	411	497	Fibronectin type III domain
EphA2_TM	PF14575	77	3e-27	81.600	521	595	521	596	Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr	PF07714	260	2.3e-102	327.800	600	858	599	858	Protein tyrosine kinase
SAM_1	PF00536	64	1.4e-24	72.600	890	952	889	953	SAM domain (Sterile alpha motif)

tumor suppressor

Ephrin_lbd (PF01404): Ephrin receptor ligand binding domain
EGF_2 (PF07974): EGF-like domain
cEGF (PF12662): Complement Clr-like EGF-like
Ephrin_rec_like (PF07699): Putative ephrin-receptor like
fn3 (PF00041): Fibronectin type III domain
EphA2_TM (PF14575): Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
SAM_1 (PF00536): SAM domain (Sterile alpha motif)

Fn1

XP_008823890.1

Domain structure obtained by HMM

Protein ID: XP_008823890.1 - fibronectin isoform X5
KEEG Ortholog ID: K05717

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
fn1	PF00039	40	0.000000000000066	38.200	53	88	53	88	Fibronectin type I domain
fn1	PF00039	40	2.2e-18	52.500	98	136	98	136	Fibronectin type I domain
fn1	PF00039	40	4.1e-17	48.500	142	180	142	180	Fibronectin type I domain
fn1	PF00039	40	9.3e-19	53.700	187	226	187	226	Fibronectin type I domain
fn1	PF00039	40	4e-19	54.900	232	271	232	271	Fibronectin type I domain
fn1	PF00039	40	0.0000000078	22.000	312	341	309	343	Fibronectin type I domain
fn2	PF00040	42	1.6e-21	62.600	361	402	361	402	Fibronectin type II domain
fn2	PF00040	42	8.8e-21	60.300	421	462	421	462	Fibronectin type II domain
fn1	PF00039	40	1.3e-18	53.200	471	509	471	509	Fibronectin type I domain
fn1	PF00039	40	1.2e-16	47.000	523	556	519	556	Fibronectin type I domain
fn1	PF00039	40	1.9e-17	49.500	562	600	562	600	Fibronectin type I domain
fn3	PF00041	85	4.8e-16	45.200	615	689	610	692	Fibronectin type III domain
fn3	PF00041	85	1.5e-16	46.900	727	798	722	801	Fibronectin type III domain
fn3	PF00041	85	1.5e-22	66.100	812	888	812	891	Fibronectin type III domain
DUF2369	PF10179	95	0.00000066	16.100	861	921	859	926	Uncharacterised conserved protein (DUF2369)
fn3	PF00041	85	3.5e-20	58.500	908	986	908	988	Fibronectin type III domain
fn3	PF00041	85	5.7e-20	57.800	998	1076	998	1078	Fibronectin type III domain
fn3	PF00041	85	0.00000000014	27.700	1096	1159	1093	1163	Fibronectin type III domain
fn3	PF00041	85	7.6e-18	51.000	1175	1254	1175	1258	Fibronectin type III domain
fn3	PF00041	85	2.6e-19	55.700	1268	1346	1268	1347	Fibronectin type III domain
fn3	PF00041	85	1.1e-21	63.300	1360	1437	1359	1439	Fibronectin type III domain
fn3	PF00041	85	1.1e-23	69.700	1450	1530	1449	1530	Fibronectin type III domain
DUF2369	PF10179	95	0.000048	10.100	1498	1540	1497	1578	Uncharacterised conserved protein (DUF2369)
fn3	PF00041	85	2.1e-22	65.600	1543	1622	1543	1623	Fibronectin type III domain
fn3	PF00041	85	2.1e-16	46.400	1634	1711	1633	1713	Fibronectin type III domain
fn3	PF00041	85	8.6e-21	60.500	1723	1798	1723	1803	Fibronectin type III domain
fn3	PF00041	85	1.3e-19	56.600	1815	1890	1815	1894	Fibronectin type III domain
fn3	PF00041	85	2.6e-21	62.100	1904	1982	1904	1984	Fibronectin type III domain
fn3	PF00041	85	0.00000000002	30.400	2093	2153	2085	2157	Fibronectin type III domain
fn1	PF00039	40	5.6e-18	51.200	2181	2220	2181	2220	Fibronectin type I domain
fn1	PF00039	40	1.3e-16	46.800	2226	2263	2226	2263	Fibronectin type I domain
fn1	PF00039	40	0.00000000000071	34.900	2270	2305	2270	2305	Fibronectin type I domain

oncogene

0.571

8.033

fn1 (PF00039): Fibronectin type I domain
fn2 (PF00040): Fibronectin type II domain
fn3 (PF00041): Fibronectin type III domain
DUF2369 (PF10179): Uncharacterised conserved protein (DUF2369)

Fnbp1l

XP_008835696.1

Domain structure obtained by HMM

Protein ID: XP_008835696.1 - formin-binding protein 1-like
KEEG Ortholog ID: K20121

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
FCH	PF00611	77	2e-23	68.800	10	87	10	88	Fes/CIP4, and EFC/F-BAR homology domain
DEDD_Tnp_IS110	PF01548	155	0.0000037	13.100	134	222	133	225	Transposase
HR1	PF02185	69	0.00000038	16.500	410	469	410	474	Hr1 repeat
CENP-Q	PF13094	155	0.025	1.000	447	476	443	480	CENP-Q, a CENPA-CAD centromere complex subunit
SH3_1	PF00018	48	1.2e-16	46.400	544	591	544	591	SH3 domain

interactor

FCH (PF00611): Fes/CIP4, and EFC/F-BAR homology domain
DEDD_Tnp_IS110 (PF01548): Transposase
HR1 (PF02185): Hr1 repeat
CENP-Q (PF13094): CENP-Q, a CENPA-CAD centromere complex subunit
SH3_1 (PF00018): SH3 domain

Gadd45gip1

XP_008853678.1

Domain structure obtained by HMM

Protein ID: XP_008853678.1 - growth arrest and DNA damage-inducible proteins-interacting protein 1

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
CR6_interact	PF10147	204	2.8e-74	235.400	15	210	1	211	Growth arrest and DNA-damage-inducible proteins-interacting protein 1

oncogene, tumor suppressor

1.000

CR6_interact (PF10147): Growth arrest and DNA-damage-inducible proteins-interacting protein 1

Got1

XP_008830168.1

Domain structure obtained by HMM

Protein ID: XP_008830168.1 - aspartate aminotransferase, cytoplasmic
KEEG Ortholog ID: K14454

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Aminotran_1_2	PF00155	363	1.5e-99	319.700	32	405	31	405	Aminotransferase class I and II

interactor

0.400

5.667

Aminotran_1_2 (PF00155): Aminotransferase class I and II

Itga4

XP_017652368.1

Domain structure obtained by HMM

Protein ID: XP_017652368.1 - integrin alpha-4
KEEG Ortholog ID: K06483

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
FG-GAP	PF01839	37	0.00000000000013	37.200	306	342	306	342	FG-GAP repeat
FG-GAP	PF01839	37	0.00000000007	28.500	371	403	369	403	FG-GAP repeat
VCBS	PF13517	61	0.0076	3.200	439	459	439	465	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
Integrin_alpha2	PF08441	467	1e-89	287.600	463	862	463	888	Integrin alpha
DUF1945	PF09178	50	0.000027	10.700	877	905	876	915	Domain of unknown function (DUF1945)
Integrin_alpha	PF00357	15	0.00000013	17.700	1001	1014	1001	1015	Integrin alpha cytoplasmic region

interactor

0.762

1.867

FG-GAP (PF01839): FG-GAP repeat
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
Integrin_alpha2 (PF08441): Integrin alpha
DUF1945 (PF09178): Domain of unknown function (DUF1945)
Integrin_alpha (PF00357): Integrin alpha cytoplasmic region

LOC103738088

XP_008836125.1

Domain structure obtained by HMM

Protein ID: XP_008836125.1 - tyrosine-protein kinase ZAP-70
KEEG Ortholog ID: K07360

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
SH2	PF00017	77	1e-20	59.900	10	87	10	87	SH2 domain
SH2	PF00017	77	1.2e-23	69.300	163	238	163	239	SH2 domain
Pkinase_Tyr	PF07714	260	6.1e-95	303.500	341	590	337	592	Protein tyrosine kinase

interactor

1.000

SH2 (PF00017): SH2 domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase

LOC103748852

XP_008849862.1

Domain structure obtained by HMM

Protein ID: XP_008849862.1 - epidermal growth factor receptor
KEEG Ortholog ID: K04361

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Recep_L_domain	PF01030	112	3.4e-34	103.600	57	167	57	168	Receptor L domain
Furin-like	PF00757	149	3.1e-33	100.900	185	338	175	338	Furin-like cysteine rich region
Recep_L_domain	PF01030	112	9.9e-33	98.900	361	480	361	481	Receptor L domain
GF_recep_IV	PF14843	132	0.0000000000000013	43.600	505	543	505	544	Growth factor receptor domain IV

interactor

0.333

13.333

Recep_L_domain (PF01030): Receptor L domain
Furin-like (PF00757): Furin-like cysteine rich region
GF_recep_IV (PF14843): Growth factor receptor domain IV

Mcm2

XP_008826791.1

Domain structure obtained by HMM

Protein ID: XP_008826791.1 - DNA replication licensing factor MCM2 isoform X1
KEEG Ortholog ID: K02540

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
MCM2_N	PF12619	153	2.9e-20	59.300	62	176	50	182	Mini-chromosome maintenance protein 2
MCM_N	PF14551	104	9.1e-20	57.500	197	285	196	288	MCM N-terminal domain
MCM_OB	PF17207	126	4.8e-41	125.800	294	420	293	422	MCM OB domain
AAA_3	PF07726	131	0.00097	5.200	421	475	401	484	ATPase family associated with various cellular activities (AAA)
MCM	PF00493	331	5.6e-144	465.300	461	802	460	803	MCM2/3/5 family

oncogene

0.444

19.333

MCM2_N (PF12619): Mini-chromosome maintenance protein 2
MCM_N (PF14551): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
AAA_3 (PF07726): ATPase family associated with various cellular activities (AAA)
MCM (PF00493): MCM2/3/5 family

Mrpl20

XP_008850816.1

Domain structure obtained by HMM

Protein ID: XP_008850816.1 - 39S ribosomal protein L20, mitochondrial isoform X1
KEEG Ortholog ID: K02887

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Ribosomal_L20	PF00453	107	6.7e-42	128.200	15	116	11	116	Ribosomal protein L20

interactor

Ribosomal_L20 (PF00453): Ribosomal protein L20

Pcbp1

XP_008821477.1

Domain structure obtained by HMM

Protein ID: XP_008821477.1 - poly(rC)-binding protein 1
KEEG Ortholog ID: K12889

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
KH_1	PF00013	66	7.4e-20	56.900	15	76	15	77	KH domain
KH_2	PF07650	78	0.000000016	20.600	79	132	74	137	KH domain
KH_1	PF00013	66	4.4e-21	60.900	99	162	99	164	KH domain
Bac_chlorC	PF02043	80	0.0000057	12.600	246	270	236	277	Bacteriochlorophyll C binding protein
KH_1	PF00013	66	3.9e-22	64.200	281	344	281	345	KH domain

oncogene

0.472

13.733

KH_1 (PF00013): KH domain
KH_2 (PF07650): KH domain
Bac_chlorC (PF02043): Bacteriochlorophyll C binding protein

Pitpna

XP_008826997.1

Domain structure obtained by HMM

Protein ID: XP_008826997.1 - phosphatidylinositol transfer protein alpha isoform

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
IP_trans	PF02121	246	1.9e-124	400.200	3	251	2	252	Phosphatidylinositol transfer protein

oncogene

1.000

IP_trans (PF02121): Phosphatidylinositol transfer protein

Ppil3

XP_008831401.1

Domain structure obtained by HMM

Protein ID: XP_008831401.1 - peptidyl-prolyl cis-trans isomerase-like 3 isoform X1
KEEG Ortholog ID: K12734

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Pro_isomerase	PF00160	159	4.1e-56	175.800	3	153	2	154	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

interactor

0.667

Pro_isomerase (PF00160): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Rpl12

XP_008823268.1

Domain structure obtained by HMM

Protein ID: XP_008823268.1 - 60S ribosomal protein L12
KEEG Ortholog ID: K02870

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Ribosomal_L11_N	PF03946	58	1.6e-30	91.000	13	69	13	69	Ribosomal protein L11, N-terminal domain
Ribosomal_L11	PF00298	70	2.2e-23	68.900	74	143	74	143	Ribosomal protein L11, RNA binding domain

interactor

0.667

2.233

Ribosomal_L11_N (PF03946): Ribosomal protein L11, N-terminal domain
Ribosomal_L11 (PF00298): Ribosomal protein L11, RNA binding domain

Taldo1

XP_008852625.1

Domain structure obtained by HMM

Protein ID: XP_008852625.1 - transaldolase
KEEG Ortholog ID: K00616

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
TAL_FSA	PF00923	287	1.4e-106	342.100	24	325	24	326	Transaldolase/Fructose-6-phosphate aldolase

interactor

0.467

7.167

TAL_FSA (PF00923): Transaldolase/Fructose-6-phosphate aldolase

Tkt

XP_008850045.1

Domain structure obtained by HMM

Protein ID: XP_008850045.1 - transketolase isoform X1
KEEG Ortholog ID: K00615

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Transketolase_N	PF00456	334	8.6e-48	149.000	17	270	14	284	Transketolase, thiamine diphosphate binding domain
Transket_pyr	PF02779	178	1.6e-45	141.100	314	475	313	478	Transketolase, pyrimidine binding domain
Transketolase_C	PF02780	124	7.6e-37	112.200	493	612	490	612	Transketolase, C-terminal domain

interactor

0.800

1.167

Transketolase_N (PF00456): Transketolase, thiamine diphosphate binding domain
Transket_pyr (PF02779): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780): Transketolase, C-terminal domain

Tktl2

XP_008846036.1

Domain structure obtained by HMM

Protein ID: XP_008846036.1 - LOW QUALITY PROTEIN: transketolase-like protein 2
KEEG Ortholog ID: K00615

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
Transketolase_N	PF00456	334	0.000000024	19.300	28	130	12	137	Transketolase, thiamine diphosphate binding domain
TPP_enzyme_C	PF02775	153	0.000011	11.500	100	146	92	149	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
Transket_pyr	PF02779	178	6.6e-23	67.400	204	354	197	358	Transketolase, pyrimidine binding domain
Transketolase_C	PF02780	124	1e-16	47.200	376	480	367	480	Transketolase, C-terminal domain

interactor

1.000

Transketolase_N (PF00456): Transketolase, thiamine diphosphate binding domain
TPP_enzyme_C (PF02775): Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
Transket_pyr (PF02779): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780): Transketolase, C-terminal domain

Vcam1

XP_008841030.1

Domain structure obtained by HMM

Protein ID: XP_008841030.1 - vascular cell adhesion protein 1
KEEG Ortholog ID: K06527

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
I-set	PF07679	90	9e-18	50.500	33	112	25	112	Immunoglobulin I-set domain
C2-set	PF05790	80	5.8e-31	92.900	133	219	133	219	Immunoglobulin C2-set domain
ig	PF00047	87	1.7e-16	46.500	228	301	227	304	Immunoglobulin domain
I-set	PF07679	90	4.2e-16	45.200	319	397	312	398	Immunoglobulin I-set domain
C2-set	PF05790	80	1.1e-30	92.000	419	507	419	507	Immunoglobulin C2-set domain
Ig_2	PF13895	79	0.000000000000013	40.700	514	593	512	596	Immunoglobulin domain
Ig_3	PF13927	79	0.000000000014	31.200	603	670	602	670	Immunoglobulin domain
V-set	PF07686	109	0.0000028	13.700	652	683	648	684	Immunoglobulin V-set domain

interactor

0.619

4.700

I-set (PF07679): Immunoglobulin I-set domain
C2-set (PF05790): Immunoglobulin C2-set domain
ig (PF00047): Immunoglobulin domain
Ig_2 (PF13895): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
V-set (PF07686): Immunoglobulin V-set domain

Zbtb43

XP_008823138.1

Domain structure obtained by HMM

Protein ID: XP_008823138.1 - zinc finger and BTB domain-containing protein 43
KEEG Ortholog ID: K10514

Domains	Pfam ID	length	E-value	Score	alifrom	alito	envfrom	envto	Description
BTB	PF00651	111	1.9e-30	91.600	23	125	23	127	BTB/POZ domain
zf-C2H2_8	PF15909	98	0.054	0.200	232	253	197	268	C2H2-type zinc ribbon
zf-C2H2	PF00096	23	0.0000066	12.900	376	394	374	394	Zinc finger, C2H2 type
zf-H2C2_2	PF13465	26	0.000000084	18.900	389	410	387	410	Zinc-finger double domain
zf-H2C2_2	PF13465	26	0.00000000011	28.000	414	437	414	437	Zinc-finger double domain
DUF2256	PF10013	40	0.0004	6.800	429	445	424	452	Uncharacterized protein conserved in bacteria (DUF2256)

interactor

BTB (PF00651): BTB/POZ domain
zf-C2H2_8 (PF15909): C2H2-type zinc ribbon
zf-C2H2 (PF00096): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465): Zinc-finger double domain
DUF2256 (PF10013): Uncharacterized protein conserved in bacteria (DUF2256)

B a c k t o T o p ⇑