Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acox1 (from a repository: Fri Apr 20 23:48:16 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)32
The number (and %) of the onco-proteins7 (21.88 %)
The number (and %) of the tumor suppressors3 (9.38 %)
Total number of binary PPIs (saturation %)49 (9.88 %)
The number (and %) of affected PPIs31 (63.27 %)
PPI diameter2
PPI radius1
The average degree of PPI2.500
Assortativity coefficient-0.3166
The network average Clustering coefficient0.260
The number (and %) of a zero Clustering coefficients21 (65.62 %)
The number (and %) of a zero Betweenness Centrality27 (84.38 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acox1
user protein310.019894.000Acyl-CoA_ox_N (PF14749): Acyl-coenzyme A oxidase N-terminal
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
ACOX (PF01756): Acyl-CoA oxidase
Acbd7
interactor100ACBP (PF00887): Acyl CoA binding protein
DUF2786 (PF10979): Protein of unknown function (DUF2786)
Adamtsl1
interactor100TSP_1 (PF00090): Thrombospondin type 1 domain
ADAM_spacer1 (PF05986): ADAM-TS Spacer 1
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
V-set (PF07686): Immunoglobulin V-set domain
PLAC (PF08686): PLAC (protease and lacunin) domain
Atoh1
interactor100HLH (PF00010): Helix-loop-helix DNA-binding domain
Boc
oncogene100Ig_3 (PF13927): Immunoglobulin domain
V-set (PF07686): Immunoglobulin V-set domain
Izumo-Ig (PF16706): Izumo-like Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
ISET-FN3_linker (PF16625): Unstructured linking region I-set and fnIII on Brother of CDO
fn3 (PF00041): Fibronectin type III domain
Cat
interactor, tumor suppressor40.6671.000Catalase (PF00199): Catalase
Catalase-rel (PF06628): Catalase-related immune-responsive
Ddx19b
interactor100DEAD (PF00270): DEAD/DEAH box helicase
PhaP_Bmeg (PF09602): Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg)
Helicase_C (PF00271): Helicase conserved C-terminal domain
Dusp14
interactor100DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Eci1
interactor100ECH_1 (PF00378): Enoyl-CoA hydratase/isomerase
Fam60a
interactor100FAM60A (PF15396): Protein Family FAM60A
Foxs1
interactor100Forkhead (PF00250): Forkhead domain
Hnrnpf
interactor21.0000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080): RNPHF zinc finger
Khdrbs2
interactor100Sam68-YY (PF16568): Tyrosine-rich domain of Sam68
LOC103729930
interactor200COX6B (PF02297): Cytochrome oxidase c subunit VIb
Litaf
tumor suppressor100DUF3824 (PF12868): Domain of unknwon function (DUF3824)
zf-LITAF-like (PF10601): LITAF-like zinc ribbon domain
M6pr
interactor100Man-6-P_recep (PF02157): Mannose-6-phosphate receptor
Mcm2
oncogene80.28615.000MCM2_N (PF12619): Mini-chromosome maintenance protein 2
MCM_N (PF14551): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
AAA_3 (PF07726): ATPase family associated with various cellular activities (AAA)
MCM (PF00493): MCM2/3/5 family
Mrpl12
interactor200Ribosomal_L12_N (PF16320): Ribosomal protein L7/L12 dimerisation domain
Ribosomal_L12 (PF00542): Ribosomal protein L7/L12 C-terminal domain
Nup62
interactor31.0000Nucleoporin_FG (PF13634): Nucleoporin FG repeat region
Nucleoporin_FG2 (PF15967): Nucleoporin FG repeated region
Nsp1_C (PF05064): Nsp1-like C-terminal region
PUMA (PF15826): Bcl-2-binding component 3, p53 upregulated modulator of apoptosis
Laminin_II (PF06009): Laminin Domain II
Pex5
interactor21.0000SHNi-TPR (PF10516): SHNi-TPR
Secretin_N_2 (PF07655): Secretin N-terminal domain
PRY (PF13765): SPRY-associated domain
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_1 (PF00515): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
Pnma1
oncogene21.0000PNMA (PF14893): PNMA
Ppwd1
interactor100WD40 (PF00400): WD domain, G-beta repeat
DUF505 (PF04458): Protein of unknown function (DUF505)
Pro_isomerase (PF00160): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Rab30
oncogene100Ras (PF00071): Ras family
Rab6b
oncogene100Ras (PF00071): Ras family
Raf1
oncogene31.0000RBD (PF02196): Raf-like Ras-binding domain
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Reck
tumor suppressor100DB (PF01682): DB module
DNA_pol_E_B (PF04042): DNA polymerase alpha/epsilon subunit B
Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
Pacifastin_I (PF05375): Pacifastin inhibitor (LCMII)
Kazal_2 (PF07648): Kazal-type serine protease inhibitor domain
VWC (PF00093): von Willebrand factor type C domain
Rida
interactor200Ribonuc_L-PSP (PF01042): Endoribonuclease L-PSP
Rplp0
interactor21.0000Ribosomal_L10 (PF00466): Ribosomal protein L10
Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
Slc2a4
interactor100Sugar_tr (PF00083): Sugar (and other) transporter
Tmed9
interactor100EMP24_GP25L (PF01105): emp24/gp25L/p24 family/GOLD
Uba5
interactor40.6671.000Pox_A_type_inc (PF04508): Viral A-type inclusion protein repeat
ThiF (PF00899): ThiF family
Ube2d2
oncogene40.6671.000UQ_con (PF00179): Ubiquitin-conjugating enzyme

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