Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acot9 (from a repository: Fri Apr 13 11:01:03 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)24
The number (and %) of the onco-proteins1 (4.17 %)
The number (and %) of the tumor suppressors1 (4.17 %)
Total number of binary PPIs (saturation %)35 (12.68 %)
The number (and %) of affected PPIs23 (65.71 %)
PPI diameter2
PPI radius1
The average degree of PPI2.333
Assortativity coefficient-0.5091
The network average Clustering coefficient0.306
The number (and %) of a zero Clustering coefficients15 (62.50 %)
The number (and %) of a zero Betweenness Centrality21 (87.50 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acot9
user protein230.020494.0004HBT (PF03061): Thioesterase superfamily
C6
interactor100TSP_1 (PF00090): Thrombospondin type 1 domain
Ldl_recept_a (PF00057): Low-density lipoprotein receptor domain class A
MACPF (PF01823): MAC/Perforin domain
Sushi (PF00084): Sushi repeat (SCR repeat)
Kazal_2 (PF07648): Kazal-type serine protease inhibitor domain
Commd10
interactor100BPL_N (PF09825): Biotin-protein ligase, N terminal
COMM_domain (PF07258): COMM domain
Epha1
oncogene, tumor suppressor100Ephrin_lbd (PF01404): Ephrin receptor ligand binding domain
Ephrin_rec_like (PF07699): Putative ephrin-receptor like
fn3 (PF00041): Fibronectin type III domain
EphA2_TM (PF14575): Ephrin type-A receptor 2 transmembrane domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
SAM_1 (PF00536): SAM domain (Sterile alpha motif)
F9
interactor100Gla (PF00594): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
EGF (PF00008): EGF-like domain
cEGF (PF12662): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
Trypsin (PF00089): Trypsin
Gfpt2
interactor100GATase_6 (PF13522): Glutamine amidotransferase domain
SIS (PF01380): SIS domain
Hibch
interactor21.0000ECH_2 (PF16113): Enoyl-CoA hydratase/isomerase
Islr
interactor100LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
LRRCT (PF01463): Leucine rich repeat C-terminal domain
I-set (PF07679): Immunoglobulin I-set domain
L3hypdh
interactor100Pro_racemase (PF05544): Proline racemase
LOC103732819
interactor30.6671.000F-box-like (PF12937): F-box-like
FBA (PF04300): F-box associated region
LOC103736112
interactor200Cadherin_2 (PF08266): Cadherin-like
Cadherin (PF00028): Cadherin domain
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
LOC103748852
interactor40.6671.000Recep_L_domain (PF01030): Receptor L domain
Furin-like (PF00757): Furin-like cysteine rich region
GF_recep_IV (PF14843): Growth factor receptor domain IV
LOC103752457
interactor200Trypsin (PF00089): Trypsin
Lamp3
interactor100Lamp (PF01299): Lysosome-associated membrane glycoprotein (Lamp)
Minos1
interactor21.0000DUF543 (PF04418): Domain of unknown function (DUF543)
Mrpl58
interactor100RF-1 (PF00472): RF-1 domain
Nanog
interactor200Homeobox (PF00046): Homeobox domain
Ndufs7
interactor31.0000Oxidored_q6 (PF01058): NADH ubiquinone oxidoreductase, 20 Kd subunit
Oxld1
interactor21.0000Oxidored-like (PF09791): Oxidoreductase-like protein, N-terminal
TAL_effector (PF03377): TAL effector repeat
Proz
interactor100Gla (PF00594): Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
EGF (PF00008): EGF-like domain
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
Trypsin (PF00089): Trypsin
Rabggtb
oncogene100Prenyltrans (PF00432): Prenyltransferase and squalene oxidase repeat
Setdb1
interactor100DUF4537 (PF15057): Domain of unknown function (DUF4537)
Agenet (PF05641): Agenet domain
MBD (PF01429): Methyl-CpG binding domain
Pre-SET (PF05033): Pre-SET motif
SET (PF00856): SET domain
Ube2a
interactor31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme
Ube2b
interactor31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme

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