Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acot8 (from a repository: Wed Apr 18 02:20:44 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins2 (18.18 %)
The number (and %) of the tumor suppressors2 (18.18 %)
Total number of binary PPIs (saturation %)17 (30.91 %)
The number (and %) of affected PPIs10 (58.82 %)
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5164
The network average Clustering coefficient0.184
The number (and %) of a zero Clustering coefficients8 (72.73 %)
The number (and %) of a zero Betweenness Centrality10 (90.91 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acot8
user protein100.02288.0004HBT_3 (PF13622): Thioesterase-like superfamily
Isg15
tumor suppressor100ubiquitin (PF00240): Ubiquitin family
Klhl23
interactor100BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Kelch_1 (PF01344): Kelch motif
Mtmr14
interactor200Y_phosphatase3 (PF13350): Tyrosine phosphatase family
Myotub-related (PF06602): Myotubularin-like phosphatase domain
Myc
oncogene31.0000Myc_N (PF01056): Myc amino-terminal region
TFIIE-A_C (PF11521): C-terminal general transcription factor TFIIE alpha
HLH (PF00010): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344): Myc leucine zipper domain
Pex5
interactor100SHNi-TPR (PF10516): SHNi-TPR
Secretin_N_2 (PF07655): Secretin N-terminal domain
PRY (PF13765): SPRY-associated domain
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_1 (PF00515): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
Pml
oncogene, tumor suppressor31.0000Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-B_box (PF00643): B-box zinc finger
DUF3583 (PF12126): Protein of unknown function (DUF3583)
Ptp4a1
interactor200ALS_ss_C (PF10369): Small subunit of acetolactate synthase
DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Ptpn3
interactor200FERM_N (PF09379): FERM N-terminal domain
FERM_M (PF00373): FERM central domain
FERM_C (PF09380): FERM C-terminal PH-like domain
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Rel
oncogene100RHD_DNA_bind (PF00554): Rel homology DNA-binding domain
RHD_dimer (PF16179): Rel homology dimerisation domain
Rnf2
interactor200zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-C4_Topoisom (PF01396): Topoisomerase DNA binding C4 zinc finger
RAWUL (PF16207): RAWUL domain RING finger- and WD40-associated ubiquitin-like

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