Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acot7 (from a repository: Thu Apr 12 12:33:30 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)29
The number (and %) of the onco-proteins7 (24.14 %)
The number (and %) of the tumor suppressors1 (3.45 %)
Total number of binary PPIs (saturation %)71 (17.49 %)
The number (and %) of affected PPIs28 (39.44 %)
PPI diameter2
PPI radius1
The average degree of PPI3.655
Assortativity coefficient-0.5951
The network average Clustering coefficient0.523
The number (and %) of a zero Clustering coefficients9 (31.03 %)
The number (and %) of a zero Betweenness Centrality18 (62.07 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acot7
user protein280.066641.6674HBT (PF03061): Thioesterase superfamily
NINJA_B (PF16136): Putative nuclear localisation signal
Aldh9a1
interactor21.0000Aldedh (PF00171): Aldehyde dehydrogenase family
Atp5a1
interactor31.0000ATP-synt_ab_N (PF02874): ATP synthase alpha/beta family, beta-barrel domain
ATP-synt_ab (PF00006): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306): ATP synthase alpha/beta chain, C terminal domain
Atxn1
interactor40.6670.667ATXN-1_C (PF12547): Capicua transcriptional repressor modulator
AXH (PF08517): Ataxin-1 and HBP1 module (AXH)
Atxn1l
interactor40.6670.667AXH (PF08517): Ataxin-1 and HBP1 module (AXH)
Btrc
oncogene31.0000Beta-TrCP_D (PF12125): D domain of beta-TrCP
F-box-like (PF12937): F-box-like
WD40 (PF00400): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Cab39l
interactor100Mo25 (PF08569): Mo25-like
Cryab
oncogene31.0000Crystallin (PF00525): Alpha crystallin A chain, N terminal
HSP20 (PF00011): Hsp20/alpha crystallin family
Dusp19
interactor200DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Dusp4
interactor200Rhodanese (PF00581): Rhodanese-like domain
DUF1610 (PF07754): Domain of unknown function (DUF1610)
DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Foxi2
interactor100Forkhead (PF00250): Forkhead domain
Gapdh
interactor, oncogene80.47610.333Gp_dh_N (PF00044): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
Gp_dh_C (PF02800): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gdi1
interactor50.6672.000GDI (PF00996): GDP dissociation inhibitor
Nhlrc2
interactor40.6671.000Thioredoxin_8 (PF13905): Thioredoxin-like
Thioredoxin (PF00085): Thioredoxin
NHL (PF01436): NHL repeat
SGL (PF08450): SMP-30/Gluconolaconase/LRE-like region
Ntrk1
oncogene120.21842.333LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Pcbp1
oncogene30.6670.667KH_1 (PF00013): KH domain
KH_2 (PF07650): KH domain
Bac_chlorC (PF02043): Bacteriochlorophyll C binding protein
Pdia3
interactor21.0000Thioredoxin (PF00085): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
Phyhipl
interactor200fn3 (PF00041): Fibronectin type III domain
Pknox1
oncogene, tumor suppressor100Meis_PKNOX_N (PF16493): N-terminal of Homeobox Meis and PKNOX1
Homeobox_KN (PF05920): Homeobox KN domain
Pot1
interactor60.7002.667POT1 (PF02765): Telomeric single stranded DNA binding POT1/CDC13
POT1PC (PF16686): ssDNA-binding domain of telomere protection protein
Zn_Tnp_IS1 (PF03811): InsA N-terminal domain
tRNA_anti-codon (PF01336): OB-fold nucleic acid binding domain
Rabgap1l
oncogene100PID (PF00640): Phosphotyrosine interaction domain (PTB/PID)
DUF3694 (PF12473): Kinesin protein
RabGAP-TBC (PF00566): Rab-GTPase-TBC domain
BST2 (PF16716): Bone marrow stromal antigen 2
HTH_Mga (PF08280): M protein trans-acting positive regulator (MGA) HTH domain
Lectin_N (PF03954): Hepatic lectin, N-terminal domain
Val_tRNA-synt_C (PF10458): Valyl tRNA synthetase tRNA binding arm
Fez1 (PF06818): Fez1
Rcc2
oncogene31.0000RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
RCC1 (PF00415): Regulator of chromosome condensation (RCC1) repeat
Relt
interactor100TNFR_c6 (PF00020): TNFR/NGFR cysteine-rich region
RELT (PF12606): Tumour necrosis factor receptor superfamily member 19
Sord
interactor40.6671.000ADH_N (PF08240): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107): Zinc-binding dehydrogenase
Terf1
interactor60.7003.000TRF (PF08558): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249): Myb-like DNA-binding domain
Thap1
interactor200THAP (PF05485): THAP domain
Tho2 (PF11262): Transcription factor/nuclear export subunit protein 2
Cep57_CLD (PF14073): Centrosome localisation domain of Cep57
Tinf2
interactor51.0000TINF2_N (PF14973): TERF1-interacting nuclear factor 2 N-terminus
Tnfaip8
interactor21.0000NiFeSe_Hases (PF00374): Nickel-dependent hydrogenase
DUF758 (PF05527): Domain of unknown function (DUF758)
Ubqln1
interactor41.0000ubiquitin (PF00240): Ubiquitin family
Fur_reg_FbpB (PF13040): Fur-regulated basic protein B
Clathrin-link (PF09268): Clathrin, heavy-chain linker
GIT_CC (PF16559): GIT coiled-coil Rho guanine nucleotide exchange factor
XPC-binding (PF09280): XPC-binding domain
DnaG_DnaB_bind (PF08278): DNA primase DnaG DnaB-binding
UBA (PF00627): UBA/TS-N domain

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