Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acot13 (from a repository: Wed Apr 11 19:27:28 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)19
The number (and %) of the onco-proteins4 (21.05 %)
The number (and %) of the tumor suppressors1 (5.26 %)
Total number of binary PPIs (saturation %)33 (19.30 %)
The number (and %) of affected PPIs19 (57.58 %)
PPI diameter2
PPI radius1
The average degree of PPI2.947
Assortativity coefficient-0.3505
The network average Clustering coefficient0.539
The number (and %) of a zero Clustering coefficients6 (31.58 %)
The number (and %) of a zero Betweenness Centrality14 (73.68 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acot13
user protein190.065271.000DUF4442 (PF14539): Domain of unknown function (DUF4442)
4HBT (PF03061): Thioesterase superfamily
Atic
oncogene30.6671.000MGS (PF02142): MGS-like domain
AICARFT_IMPCHas (PF01808): AICARFT/IMPCHase bienzyme
Eci2
interactor31.0000ACBP (PF00887): Acyl CoA binding protein
ECH_1 (PF00378): Enoyl-CoA hydratase/isomerase
Fn1
oncogene60.33310.000fn1 (PF00039): Fibronectin type I domain
fn2 (PF00040): Fibronectin type II domain
fn3 (PF00041): Fibronectin type III domain
DUF2369 (PF10179): Uncharacterised conserved protein (DUF2369)
Klc2
interactor100TMF_TATA_bd (PF12325): TATA element modulatory factor 1 TATA binding
KASH_CCD (PF14662): Coiled-coil region of CCDC155 or KASH
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_10 (PF13374): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
Kpna2
interactor21.0000IBB (PF01749): Importin beta binding domain
Arm (PF00514): Armadillo/beta-catenin-like repeat
Arm_3 (PF16186): Atypical Arm repeat
Lman2l
interactor100Lectin_leg-like (PF03388): Legume-like lectin family
PMP1_2 (PF08114): ATPase proteolipid family
Ndufaf2
interactor100NDUFA12 (PF05071): NADH ubiquinone oxidoreductase subunit NDUFA12
Ndufs3
interactor50.5003.000Complex1_30kDa (PF00329): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
Pctp
interactor100START (PF01852): START domain
Pdia6
interactor21.0000Thioredoxin (PF00085): Thioredoxin
FAD_binding_7 (PF03441): FAD binding domain of DNA photolyase
Thioredoxin_6 (PF13848): Thioredoxin-like domain
Ptpa
oncogene, tumor suppressor100PTPA (PF03095): Phosphotyrosyl phosphate activator (PTPA) protein
Pus7
interactor21.0000TruD (PF01142): tRNA pseudouridine synthase D (TruD)
Rbbp6
oncogene21.0000DWNN (PF08783): DWNN domain
zf-CCHC_2 (PF13696): Zinc knuckle
U-box (PF04564): U-box domain
Ndc1_Nup (PF09531): Nucleoporin protein Ndc1-Nup
DUF1777 (PF08648): Protein of unknown function (DUF1777)
TMEM171 (PF15471): Transmembrane protein family 171
IncA (PF04156): IncA protein
DUF936 (PF06075): Plant protein of unknown function (DUF936)
FXMRP1_C_core (PF12235): Fragile X-related 1 protein core C terminal
Pheromone (PF08015): Fungal mating-type pheromone
Auxin_canalis (PF05703): Auxin canalisation
Sbds
oncogene100SBDS (PF01172): Shwachman-Bodian-Diamond syndrome (SBDS) protein
SBDS_C (PF09377): SBDS protein C-terminal domain
Snu13
interactor40.6671.000Ribosomal_L7Ae (PF01248): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Trnt1
interactor21.0000PolyA_pol (PF01743): Poly A polymerase head domain
PolyA_pol_RNAbd (PF12627): Probable RNA and SrmB- binding site of polymerase A
Imm64 (PF15600): Immunity protein 64
Tsfm
interactor21.0000ARA70 (PF12489): Nuclear coactivator
EF_TS (PF00889): Elongation factor TS
Ube2n
interactor31.0000UQ_con (PF00179): Ubiquitin-conjugating enzyme

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