Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acot12 (from a repository: Thu Apr 12 16:33:20 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins1 (16.67 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)6 (40.00 %)
The number (and %) of affected PPIs5 (83.33 %)
PPI diameter2
PPI radius1
The average degree of PPI1.667
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients6 (100.00 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure		 Type Number
of PPI (degree)		 Clustering
Coefficient		 Betweenness
Centrality		 Domains (Pfam ID): description
Acot12

Domain structure obtained by HMM

Protein ID: XP_008851534.1 - acyl-coenzyme A thioesterase 12
KEEG Ortholog ID: K01067
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
4HBTPF03061790.00000000000001940.20027952497Thioesterase superfamily
4HBTPF03061795e-1748.400197271197274Thioesterase superfamily
STARTPF018522094.1e-2264.700355512350514START domain
user protein5020.0004HBT (PF03061): Thioesterase superfamily
START (PF01852): START domain
Acot11

Domain structure obtained by HMM

Protein ID: XP_008831214.1 - acyl-coenzyme A thioesterase 11 isoform X1
KEEG Ortholog ID: K12417
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
4HBTPF03061790.000000000003732.8006813463136Thioesterase superfamily
4HBTPF03061798.5e-1644.400235304235311Thioesterase superfamily
STARTPF018522092.4e-38117.700386551385554START domain
interactor2004HBT (PF03061): Thioesterase superfamily
START (PF01852): START domain
Inppl1

Domain structure obtained by HMM

Protein ID: XP_008852272.1 - phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1
KEEG Ortholog ID: K15909
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
SH2PF00017771.4e-1956.3002110221102SH2 domain
Exo_endo_phosPF033721130.0000000002426.900430719430719Endonuclease/Exonuclease/phosphatase family
SAM_1PF00536640.00000000000233.7001203125612011259SAM domain (Sterile alpha motif)
oncogene100SH2 (PF00017): SH2 domain
Exo_endo_phos (PF03372): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536): SAM domain (Sterile alpha motif)
Spag9

Domain structure obtained by HMM

Protein ID: XP_008836608.1 - C-Jun-amino-terminal kinase-interacting protein 4 isoform X1
KEEG Ortholog ID: K20317
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
Jnk-SapK_ap_NPF097441563.1e-62195.60051595160JNK_SAPK-associated protein-1
DUF501PF044171410.00174.40011617595182Protein of unknown function (DUF501)
JIP_LZIIPF16471715.6e-34102.500394464394464JNK-interacting protein leucine zipper II
DUF972PF061561020.0000211.500421480419496Protein of unknown function (DUF972)
ERMPF007692430.000157.700437628416629Ezrin/radixin/moesin family
TACCPF050102010.000476.100604647593649Transforming acidic coiled-coil-containing protein (TACC)
IncAPF041561900.0000668.900698744695753IncA protein
Alanine_zipperPF11839970.00056.700832889827901Alanine-zipper, major outer membrane lipoprotein
FYDLN_acidPF095381060.0361.100862898837937Protein of unknown function (FYDLN_acid)
interactor100Jnk-SapK_ap_N (PF09744): JNK_SAPK-associated protein-1
DUF501 (PF04417): Protein of unknown function (DUF501)
JIP_LZII (PF16471): JNK-interacting protein leucine zipper II
DUF972 (PF06156): Protein of unknown function (DUF972)
ERM (PF00769): Ezrin/radixin/moesin family
TACC (PF05010): Transforming acidic coiled-coil-containing protein (TACC)
IncA (PF04156): IncA protein
Alanine_zipper (PF11839): Alanine-zipper, major outer membrane lipoprotein
FYDLN_acid (PF09538): Protein of unknown function (FYDLN_acid)
Tlr5

Domain structure obtained by HMM

Protein ID: XP_008821970.1 - toll-like receptor 5
KEEG Ortholog ID: K10168
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
LRR_8PF13855610.00001810.70049784679Leucine rich repeat
LRR_8PF13855612.7e-1748.7008513183131Leucine rich repeat
LRR_8PF13855610.000000001124.200135182134182Leucine rich repeat
LRR_1PF00560230.0192.400171190171198Leucine Rich Repeat
LRR_6PF13516240.00165.100227237225237Leucine Rich repeat
LRR_8PF13855610.0000000000002735.800291348288348Leucine rich repeat
LRR_8PF13855610.0000000000001336.800341396341396Leucine rich repeat
LRR_4PF12799430.00004110.300384413384443Leucine Rich repeats (2 copies)
LRR_4PF12799430.000007212.700448486448491Leucine Rich repeats (2 copies)
LRR_4PF12799430.000004913.200474515474525Leucine Rich repeats (2 copies)
LRR_8PF13855611e-1646.800492538491538Leucine rich repeat
LRR_8PF13855610.0000000003725.800528580527581Leucine rich repeat
LRR_1PF00560230.00354.700570583570593Leucine Rich Repeat
TIRPF015821761.7e-33102.000693846692857TIR domain
interactor100LRR_8 (PF13855): Leucine rich repeat
LRR_1 (PF00560): Leucine Rich Repeat
LRR_6 (PF13516): Leucine Rich repeat
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
TIR (PF01582): TIR domain
Zmym6

Domain structure obtained by HMM

Protein ID: XP_008827460.1 - zinc finger MYM-type protein 6
DomainsPfam IDlengthE-valueScorealifromalitoenvfromenvtoDescription
zf-FCSPF06467410.0000001717.4007910975110MYM-type Zinc finger with FCS sequence motif
zf-FCSPF06467410.0000000000002236.300121161120161MYM-type Zinc finger with FCS sequence motif
DUF2116PF09889590.00184.600149166145173Uncharacterized protein containing a Zn-ribbon (DUF2116)
zf-FCSPF06467410.0015.400211227199228MYM-type Zinc finger with FCS sequence motif
zf-FCSPF06467410.00001711.100241272238275MYM-type Zinc finger with FCS sequence motif
RPAP2_Rtr1PF04181750.00115.600257280244281Rtr1/RPAP2 family
zf-FCSPF06467410.00000003319.700353387351387MYM-type Zinc finger with FCS sequence motif
zf-FCSPF06467410.0000000002726.400393425392425MYM-type Zinc finger with FCS sequence motif
zf-FCSPF06467410.0000007915.300439474438474MYM-type Zinc finger with FCS sequence motif
C1_1PF00130530.000267.200466489452490Phorbol esters/diacylglycerol binding domain (C1 domain)
zf-FCSPF06467410.0000003916.300481515479515MYM-type Zinc finger with FCS sequence motif
zf-BEDPF02892440.000001514.500699730687730BED zinc finger
DUF4371PF142912360.00001411.000817921790927Domain of unknown function (DUF4371)
interactor100zf-FCS (PF06467): MYM-type Zinc finger with FCS sequence motif
DUF2116 (PF09889): Uncharacterized protein containing a Zn-ribbon (DUF2116)
RPAP2_Rtr1 (PF04181): Rtr1/RPAP2 family
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
zf-BED (PF02892): BED zinc finger
DUF4371 (PF14291): Domain of unknown function (DUF4371)

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