Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aco1 (from a repository: Sun Apr 22 01:06:01 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)17
The number (and %) of the onco-proteins2 (11.76 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)43 (31.62 %)
The number (and %) of affected PPIs16 (37.21 %)
PPI diameter2
PPI radius1
The average degree of PPI4.118
Assortativity coefficient-0.5482
The network average Clustering coefficient0.560
The number (and %) of a zero Clustering coefficients3 (17.65 %)
The number (and %) of a zero Betweenness Centrality7 (41.18 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aco1
user protein160.158167.500Aconitase (PF00330): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694): Aconitase C-terminal domain
App
interactor41.0000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Ctps1
interactor41.0000CTP_synth_N (PF06418): CTP synthase N-terminus
GATase (PF00117): Glutamine amidotransferase class-I
Dcps
interactor31.0000DcpS (PF05652): Scavenger mRNA decapping enzyme (DcpS) N-terminal
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
Fbxl5
interactor200Hemerythrin (PF01814): Hemerythrin HHE cation binding domain
F-box-like (PF12937): F-box-like
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
LRR_6 (PF13516): Leucine Rich repeat
Fubp1
oncogene30.6671.000KH_1 (PF00013): KH domain
DUF1897 (PF09005): Domain of unknown function (DUF1897)
CYSTM (PF12734): Cysteine-rich TM module stress tolerance
Gbe1
interactor100CBM_48 (PF02922): Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
Alpha-amylase (PF00128): Alpha amylase, catalytic domain
Alpha-amylase_C (PF02806): Alpha amylase, C-terminal all-beta domain
LOC103732255
interactor40.6671.500Enolase_N (PF03952): Enolase, N-terminal domain
Enolase_C (PF00113): Enolase, C-terminal TIM barrel domain
LOC103746136
interactor70.4007.667Histone (PF00125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211): C-terminus of histone H2A
DUF1764 (PF08576): Eukaryotic protein of unknown function (DUF1764)
Macro (PF01661): Macro domain
Lgals1
interactor30.6671.000Gal-bind_lectin (PF00337): Galactoside-binding lectin
Mov10
interactor40.6671.167AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
Ntrk1
oncogene90.35716.667LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Nxf1
interactor40.6670.667Tap-RNA_bind (PF09162): Tap, RNA-binding
LRR_8 (PF13855): Leucine rich repeat
NTF2 (PF02136): Nuclear transport factor 2 (NTF2) domain
TAP_C (PF03943): TAP C-terminal domain
Psmg1
interactor31.0000PAC1 (PF16094): Proteasome assembly chaperone 4
Shmt2
interactor40.6671.500SHMT (PF00464): Serine hydroxymethyltransferase
Strap
interactor60.6003.333WD40 (PF00400): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Txndc17
interactor100Glutaredoxin (PF00462): Glutaredoxin
DUF953 (PF06110): Eukaryotic protein of unknown function (DUF953)

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