Acly
| user protein | 57 | 0.137 | 1838.567 | ATP-grasp_2 (PF08442): ATP-grasp domain Citrate_bind (PF16114): ATP citrate lyase citrate-binding CoA_binding (PF02629): CoA binding domain Ligase_CoA (PF00549): CoA-ligase Citrate_synt (PF00285): Citrate synthase, C-terminal domain |
Ahsa1
| interactor | 10 | 0.556 | 9.652 | MdcG (PF10620): Phosphoribosyl-dephospho-CoA transferase MdcG AHSA1 (PF08327): Activator of Hsp90 ATPase homolog 1-like protein |
App
| interactor | 20 | 0.275 | 85.472 | APP_N (PF02177): Amyloid A4 N-terminal heparin-binding APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD SDA1 (PF05285): SDA1 YtxH (PF12732): YtxH-like protein Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_E2 (PF12925): E2 domain of amyloid precursor protein Beta-APP (PF03494): Beta-amyloid peptide (beta-APP) APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus |
Asb15
| interactor | 1 | 0 | 0 | Ank_2 (PF12796): Ankyrin repeats (3 copies) SOCS_box (PF07525): SOCS box |
Bag3
| oncogene | 8 | 0.476 | 6.917 | WW (PF00397): WW domain RNA_pol_Rpc4 (PF05132): RNA polymerase III RPC4 DUF4124 (PF13511): Domain of unknown function (DUF4124) BAG (PF02179): BAG domain Rib_recp_KP_reg (PF05104): Ribosome receptor lysine/proline rich region |
Cand1
| interactor | 21 | 0.411 | 63.350 | HEAT_2 (PF13646): HEAT repeats Cnd1 (PF12717): non-SMC mitotic condensation complex subunit 1 HEAT_EZ (PF13513): HEAT-like repeat DUF3385 (PF11865): Domain of unknown function (DUF3385) Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region HEAT (PF02985): HEAT repeat MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C (PF12460): RNAPII transcription regulator C-terminal Adaptin_N (PF01602): Adaptin N terminal region TIP120 (PF08623): TATA-binding protein interacting (TIP20) |
Cry1
| interactor | 6 | 0.800 | 0.472 | DNA_photolyase (PF00875): DNA photolyase FAD_binding_7 (PF03441): FAD binding domain of DNA photolyase |
Cry2
| interactor | 9 | 0.714 | 2.662 | DNA_photolyase (PF00875): DNA photolyase FAD_binding_7 (PF03441): FAD binding domain of DNA photolyase |
Cs
| interactor | 6 | 0.667 | 2.250 | Citrate_synt (PF00285): Citrate synthase, C-terminal domain |
Cth
| interactor | 3 | 1.000 | 0 | Cys_Met_Meta_PP (PF01053): Cys/Met metabolism PLP-dependent enzyme |
Cul2
| tumor suppressor | 13 | 0.538 | 21.060 | Cullin (PF00888): Cullin family Cullin_Nedd8 (PF10557): Cullin protein neddylation domain |
Cul3
| interactor | 20 | 0.433 | 45.256 | Cullin (PF00888): Cullin family WAC_Acf1_DNA_bd (PF10537): ATP-utilising chromatin assembly and remodelling N-terminal Cullin_Nedd8 (PF10557): Cullin protein neddylation domain |
Cul7
| interactor | 15 | 0.451 | 18.891 | Cul7 (PF11515): Mouse development and cellular proliferation protein Cullin-7 ANAPC10 (PF03256): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888): Cullin family Cullin_Nedd8 (PF10557): Cullin protein neddylation domain |
Ddias
| interactor | 1 | 0 | 0 | Rep_fac-A_C (PF08646): Replication factor-A C terminal domain FYVE (PF01363): FYVE zinc finger YgbA_NO (PF11756): Nitrous oxide-stimulated promoter Peptidase_A2B (PF12384): Ty3 transposon peptidase |
Derl1
| interactor | 6 | 0.700 | 0.765 | DER1 (PF04511): Der1-like family |
Eef1d
| interactor | 13 | 0.515 | 11.560 | Cytochrom_C_2 (PF01322): Cytochrome C' PGA2 (PF07543): Protein trafficking PGA2 UPF0565 (PF10561): Uncharacterised protein family UPF0565 EF-1_beta_acid (PF10587): Eukaryotic elongation factor 1 beta central acidic region EF1_GNE (PF00736): EF-1 guanine nucleotide exchange domain |
Fn1
| oncogene | 14 | 0.462 | 17.077 | fn1 (PF00039): Fibronectin type I domain fn2 (PF00040): Fibronectin type II domain fn3 (PF00041): Fibronectin type III domain DUF2369 (PF10179): Uncharacterised conserved protein (DUF2369) |
Gsk3b
| oncogene, tumor suppressor | 4 | 0.667 | 0.667 | Pkinase (PF00069): Protein kinase domain |
Hdac5
| interactor | 8 | 0.524 | 5.833 | HDAC4_Gln (PF12203): Glutamine rich N terminal domain of histone deacetylase 4 TFIIA (PF03153): Transcription factor IIA, alpha/beta subunit PTPRCAP (PF15713): Protein tyrosine phosphatase receptor type C-associated Hist_deacetyl (PF00850): Histone deacetylase domain |
Hgs
| interactor | 5 | 0.700 | 0.715 | VHS (PF00790): VHS domain FYVE (PF01363): FYVE zinc finger UIM (PF02809): Ubiquitin interaction motif EF-1_beta_acid (PF10587): Eukaryotic elongation factor 1 beta central acidic region DUF3306 (PF11748): Protein of unknown function (DUF3306) Hrs_helical (PF12210): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917): Piezo |
Hnrnpk
| oncogene | 25 | 0.362 | 110.631 | ROKNT (PF08067): ROKNT (NUC014) domain KH_1 (PF00013): KH domain |
Huwe1
| oncogene | 19 | 0.412 | 41.708 | DUF908 (PF06012): Domain of Unknown Function (DUF908) DUF913 (PF06025): Domain of Unknown Function (DUF913) PBP_sp32 (PF07222): Proacrosin binding protein sp32 UBA (PF00627): UBA/TS-N domain U1snRNP70_N (PF12220): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FdhE (PF04216): Protein involved in formate dehydrogenase formation WWE (PF02825): WWE domain BSP_II (PF05432): Bone sialoprotein II (BSP-II) Ku_C (PF03730): Ku70/Ku80 C-terminal arm RNA_pol_Rpc4 (PF05132): RNA polymerase III RPC4 TFIIA (PF03153): Transcription factor IIA, alpha/beta subunit Tim54 (PF11711): Inner membrane protein import complex subunit Tim54 Nop14 (PF04147): Nop14-like family DUF4414 (PF14377): Domain of unknown function (DUF4414) Mucin (PF01456): Mucin-like glycoprotein BUD22 (PF09073): BUD22 HABP4_PAI-RBP1 (PF04774): Hyaluronan / mRNA binding family HECT (PF00632): HECT-domain (ubiquitin-transferase) |
Ikbke
| interactor | 3 | 1.000 | 0 | Pkinase (PF00069): Protein kinase domain zf-RING_9 (PF13901): Putative zinc-RING and/or ribbon TPR_MLP1_2 (PF07926): TPR/MLP1/MLP2-like protein |
Isg15
| tumor suppressor | 4 | 0.833 | 0.500 | ubiquitin (PF00240): Ubiquitin family |
Kat2b
| interactor | 3 | 1.000 | 0 | PCAF_N (PF06466): PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_1 (PF00583): Acetyltransferase (GNAT) family Bromodomain (PF00439): Bromodomain |
Kpna2
| interactor | 14 | 0.473 | 20.402 | IBB (PF01749): Importin beta binding domain Arm (PF00514): Armadillo/beta-catenin-like repeat Arm_3 (PF16186): Atypical Arm repeat |
Kpna4
| interactor | 6 | 0.733 | 1.486 | IBB (PF01749): Importin beta binding domain Arm (PF00514): Armadillo/beta-catenin-like repeat Arm_3 (PF16186): Atypical Arm repeat |
LOC103730663
| interactor | 8 | 0.571 | 7.548 | Ank_4 (PF13637): Ankyrin repeats (many copies) Ank (PF00023): Ankyrin repeat Ank_5 (PF13857): Ankyrin repeats (many copies) |
Mcm2
| oncogene | 26 | 0.347 | 107.732 | MCM2_N (PF12619): Mini-chromosome maintenance protein 2 MCM_N (PF14551): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain AAA_3 (PF07726): ATPase family associated with various cellular activities (AAA) MCM (PF00493): MCM2/3/5 family |
Mcm6
| interactor | 12 | 0.418 | 13.080 | MCM_N (PF14551): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain MCM (PF00493): MCM2/3/5 family Jnk-SapK_ap_N (PF09744): JNK_SAPK-associated protein-1 YmgB (PF10798): Biofilm development protein YmgB/AriR |
Naprt
| interactor | 2 | 1.000 | 0 | NAPRTase (PF04095): Nicotinate phosphoribosyltransferase (NAPRTase) family |
Ncl
| interactor | 21 | 0.447 | 48.971 | PBP1_TM (PF14812): Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 (PF05764): YL1 nuclear protein Myc_N (PF01056): Myc amino-terminal region ANAPC15 (PF15243): Anaphase-promoting complex subunit 15 Sigma70_ner (PF04546): Sigma-70, non-essential region RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608): Limkain b1 |
Nme1
| tumor suppressor | 6 | 0.800 | 1.067 | NDK (PF00334): Nucleoside diphosphate kinase |
Ntrk1
| oncogene | 25 | 0.341 | 102.894 | LRR_8 (PF13855): Leucine rich repeat TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain Ig_3 (PF13927): Immunoglobulin domain I-set (PF07679): Immunoglobulin I-set domain Pkinase_Tyr (PF07714): Protein tyrosine kinase |
Nup107
| interactor | 7 | 0.381 | 5.600 | Nup84_Nup100 (PF04121): Nuclear pore protein 84 / 107 |
Nup210l
| interactor | 1 | 0 | 0 | T2SS-T3SS_pil_N (PF13629): Pilus formation protein N terminal region Big_2 (PF02368): Bacterial Ig-like domain (group 2) |
Obsl1
| interactor | 13 | 0.515 | 11.295 | I-set (PF07679): Immunoglobulin I-set domain Herpes_gE (PF02480): Alphaherpesvirus glycoprotein E fn3 (PF00041): Fibronectin type III domain Ig_3 (PF13927): Immunoglobulin domain BiPBP_C (PF06832): Penicillin-Binding Protein C-terminus Family Ig_4 (PF16680): T-cell surface glycoprotein CD3 delta chain |
Ppp6c
| interactor | 3 | 1.000 | 0 | Metallophos (PF00149): Calcineurin-like phosphoesterase |
Prkab1
| interactor, oncogene | 3 | 0.667 | 0.500 | AMPK1_CBM (PF16561): Glycogen recognition site of AMP-activated protein kinase AMPKBI (PF04739): 5'-AMP-activated protein kinase beta subunit, interaction domain |
Prmt1
| interactor | 18 | 0.515 | 26.623 | Methyltransf_25 (PF13649): Methyltransferase domain Methyltransf_23 (PF13489): Methyltransferase domain |
Pygb
| interactor | 6 | 0.700 | 0.806 | Phosphorylase (PF00343): Carbohydrate phosphorylase |
Rpe
| interactor | 3 | 1.000 | 0 | Ribul_P_3_epim (PF00834): Ribulose-phosphate 3 epimerase family OMPdecase (PF00215): Orotidine 5'-phosphate decarboxylase / HUMPS family |
Sdha
| tumor suppressor | 12 | 0.470 | 16.902 | FAD_binding_2 (PF00890): FAD binding domain Succ_DH_flav_C (PF02910): Fumarate reductase flavoprotein C-term |
Sdhb
| oncogene, tumor suppressor | 6 | 0.800 | 1.300 | Fer2_3 (PF13085): 2Fe-2S iron-sulfur cluster binding domain Fer4_8 (PF13183): 4Fe-4S dicluster domain Fer4_17 (PF13534): 4Fe-4S dicluster domain |
Shc1
| oncogene | 4 | 0.667 | 0.182 | PID (PF00640): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017): SH2 domain |
Sirt2
| tumor suppressor | 1 | 0 | 0 | SIR2 (PF02146): Sir2 family |
Sirt6
| tumor suppressor | 2 | 1.000 | 0 | SIR2 (PF02146): Sir2 family TPP_enzyme_M (PF00205): Thiamine pyrophosphate enzyme, central domain |
Sirt7
| interactor | 12 | 0.318 | 22.098 | DUF563 (PF04577): Protein of unknown function (DUF563) SIR2 (PF02146): Sir2 family |
Srrt
| interactor | 9 | 0.611 | 6.787 | DUF3546 (PF12066): Domain of unknown function (DUF3546) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 TRAP_alpha (PF03896): Translocon-associated protein (TRAP), alpha subunit RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 (PF13821): Domain of unknown function (DUF4187) ARS2 (PF04959): Arsenite-resistance protein 2 |
Stau1
| interactor | 12 | 0.673 | 4.474 | dsrm (PF00035): Double-stranded RNA binding motif Staufen_C (PF16482): Staufen C-terminal domain |
Stip1
| interactor | 8 | 0.571 | 4.771 | TPR_11 (PF13414): TPR repeat TPR_2 (PF07719): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_1 (PF00515): Tetratricopeptide repeat Wtap (PF17098): WTAP/Mum2p family DREPP (PF05558): DREPP plasma membrane polypeptide TPR_12 (PF13424): Tetratricopeptide repeat |
Terf1
| interactor | 9 | 0.536 | 7.672 | TRF (PF08558): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249): Myb-like DNA-binding domain |
Terf2
| interactor | 7 | 0.733 | 1.648 | TRF (PF08558): Telomere repeat binding factor (TRF) TERF2_RBM (PF16772): Telomeric repeat-binding factor 2 Rap1-binding motif Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain Myb_DNA-binding (PF00249): Myb-like DNA-binding domain |
Tfe3
| oncogene | 3 | 1.000 | 0 | MITF_TFEB_C_3_N (PF15951): MITF/TFEB/TFEC/TFE3 N-terminus HLH (PF00010): Helix-loop-helix DNA-binding domain DUF3371 (PF11851): Domain of unknown function (DUF3371) |
Ubc
| interactor | 18 | 0.426 | 50.131 | ubiquitin (PF00240): Ubiquitin family |
Ubr4
| interactor | 4 | 0.667 | 0.508 | FAM176 (PF14851): FAM176 family CAP_N (PF01213): Adenylate cyclase associated (CAP) N terminal zf-UBR (PF02207): Putative zinc finger in N-recognin (UBR box) Pheromone (PF08015): Fungal mating-type pheromone Ribosomal_60s (PF00428): 60s Acidic ribosomal protein AP3D1 (PF06375): AP-3 complex subunit delta-1 RecR (PF02132): RecR protein DZR (PF12773): Double zinc ribbon E3_UbLigase_R4 (PF13764): E3 ubiquitin-protein ligase UBR4 |
Usp13
| interactor | 2 | 1.000 | 0 | zf-UBP (PF02148): Zn-finger in ubiquitin-hydrolases and other protein UCH (PF00443): Ubiquitin carboxyl-terminal hydrolase |
Znf746
| interactor | 7 | 0.400 | 5.519 | DUF3669 (PF12417): Zinc finger protein KRAB (PF01352): KRAB box zf-H2C2_2 (PF13465): Zinc-finger double domain zf-C2H2 (PF00096): Zinc finger, C2H2 type Period_C (PF12114): Period protein 2/3C-terminal region zf-C2H2_11 (PF16622): zinc-finger C2H2-type |