Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acbd3 (from a repository: Thu Apr 12 19:15:35 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins4 (28.57 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)36 (39.56 %)
The number (and %) of affected PPIs13 (36.11 %)
PPI diameter2
PPI radius1
The average degree of PPI4.000
Assortativity coefficient-0.5624
The network average Clustering coefficient0.571
The number (and %) of a zero Clustering coefficients4 (28.57 %)
The number (and %) of a zero Betweenness Centrality9 (64.29 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acbd3
user protein130.192107.667ACBP (PF00887): Acyl CoA binding protein
U79_P34 (PF03064): HSV U79 / HCMV P34
TFIIA (PF03153): Transcription factor IIA, alpha/beta subunit
GOLD_2 (PF13897): Golgi-dynamics membrane-trafficking
Cul3
interactor60.8001.333Cullin (PF00888): Cullin family
WAC_Acf1_DNA_bd (PF10537): ATP-utilising chromatin assembly and remodelling N-terminal
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Eftud2
interactor60.8001.333EFTUD2 (PF16004): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
GTP_EFTU (PF00009): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144): Elongation factor Tu domain 2
EFG_II (PF14492): Elongation Factor G, domain II
EFG_IV (PF03764): Elongation factor G, domain IV
EFG_C (PF00679): Elongation factor G C-terminus
Elavl1
oncogene60.7003.000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Hars
interactor41.0000WHEP-TRS (PF00458): WHEP-TRS domain
tRNA-synt_His (PF13393): Histidyl-tRNA synthetase
Sugarporin_N (PF11471): Maltoporin periplasmic N-terminal extension
HGTP_anticodon (PF03129): Anticodon binding domain
Kdm2b
oncogene200Cupin_8 (PF13621): Cupin-like domain
zf-CXXC (PF02008): CXXC zinc finger domain
PHD_4 (PF16866): PHD-finger
F-box (PF00646): F-box domain
LRR_8 (PF13855): Leucine rich repeat
LRR_6 (PF13516): Leucine Rich repeat
LOC103728443
interactor100Pro_isomerase (PF00160): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Lrfn4
interactor100LRR_8 (PF13855): Leucine rich repeat
LRRCT (PF01463): Leucine rich repeat C-terminal domain
I-set (PF07679): Immunoglobulin I-set domain
fn3 (PF00041): Fibronectin type III domain
Ntrk1
oncogene90.50012.667LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Pkn2
interactor31.0000HR1 (PF02185): Hr1 repeat
SKA2 (PF16740): Spindle and kinetochore-associated protein 2
C2 (PF00168): C2 domain
Pkinase (PF00069): Protein kinase domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Sars
interactor41.0000Seryl_tRNA_N (PF02403): Seryl-tRNA synthetase N-terminal domain
NOD (PF06816): NOTCH protein
tRNA-synt_2b (PF00587): tRNA synthetase class II core domain (G, H, P, S and T)
DUF1840 (PF08895): Domain of unknown function (DUF1840)
Smurf2
interactor200C2 (PF00168): C2 domain
WW (PF00397): WW domain
HECT (PF00632): HECT-domain (ubiquitin-transferase)
Srsf2
oncogene51.0000Transformer (PF06495): Fruit fly transformer protein
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2457 (PF10446): Protein of unknown function (DUF2457)
Apt1 (PF10351): Golgi-body localisation protein domain
TP2 (PF01254): Nuclear transition protein 2
Unc45a
interactor21.0000TPR_16 (PF13432): Tetratricopeptide repeat
TPR_2 (PF07719): Tetratricopeptide repeat
UNC45-central (PF11701): Myosin-binding striated muscle assembly central
Arm (PF00514): Armadillo/beta-catenin-like repeat
RIX1 (PF08167): rRNA processing/ribosome biogenesis
HEAT_2 (PF13646): HEAT repeats
VasI (PF11319): Type VI secretion system VasI, EvfG, VC_A0118
HEAT_PBS (PF03130): PBS lyase HEAT-like repeat

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