Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acap1 (from a repository: Thu Apr 12 14:29:09 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)7
The number (and %) of the onco-proteins4 (57.14 %)
The number (and %) of the tumor suppressors1 (14.29 %)
Total number of binary PPIs (saturation %)9 (42.86 %)
The number (and %) of affected PPIs6 (66.67 %)
PPI diameter2
PPI radius1
The average degree of PPI1.714
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients7 (100.00 %)
The number (and %) of a zero Betweenness Centrality6 (85.71 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acap1
user protein, oncogene6030.000BAR_3 (PF16746): BAR domain of APPL family
PH (PF00169): PH domain
ArfGap (PF01412): Putative GTPase activating protein for Arf
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_2 (PF12796): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
Akt1
oncogene200PH (PF00169): PH domain
Pkinase (PF00069): Protein kinase domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Bop1
oncogene200SDA1 (PF05285): SDA1
BOP1NT (PF08145): BOP1NT (NUC169) domain
WD40 (PF00400): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
Grb2
oncogene200SH3_1 (PF00018): SH3 domain
SH2 (PF00017): SH2 domain
DUF5093 (PF17011): Domain of unknown function (DUF5093)
Itgb1
tumor suppressor100PSI_integrin (PF17205): Integrin plexin domain
Integrin_beta (PF00362): Integrin beta chain VWA domain
EGF_2 (PF07974): EGF-like domain
Integrin_B_tail (PF07965): Integrin beta tail domain
Integrin_b_cyt (PF08725): Integrin beta cytoplasmic domain
Rab11fip3
interactor100EF-hand_7 (PF13499): EF-hand domain pair
XhlA (PF10779): Haemolysin XhlA
GIT_CC (PF16559): GIT coiled-coil Rho guanine nucleotide exchange factor
bZIP_1 (PF00170): bZIP transcription factor
DUF1664 (PF07889): Protein of unknown function (DUF1664)
WD40_alt (PF14077): Alternative WD40 repeat motif
ZapB (PF06005): Cell division protein ZapB
RBD-FIP (PF09457): FIP domain
Rabgap1l
oncogene100PID (PF00640): Phosphotyrosine interaction domain (PTB/PID)
DUF3694 (PF12473): Kinesin protein
RabGAP-TBC (PF00566): Rab-GTPase-TBC domain
BST2 (PF16716): Bone marrow stromal antigen 2
HTH_Mga (PF08280): M protein trans-acting positive regulator (MGA) HTH domain
Lectin_N (PF03954): Hepatic lectin, N-terminal domain
Val_tRNA-synt_C (PF10458): Valyl tRNA synthetase tRNA binding arm
Fez1 (PF06818): Fez1

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