Find Protein-Protein Interactions (PPI) Network

Choose & Enter
Choose animal: Visualization driver:
Protein/NCBI_ID(s):
Refseq_ID(s):
KEGG_KO(s):


Level of PPIs:
or Upload text file:
Update repository

Visible interactions: Visible interactors: Size of node:

Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acadvl (from a repository: Fri Apr 13 10:16:06 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)31
The number (and %) of the onco-proteins4 (12.90 %)
The number (and %) of the tumor suppressors3 (9.68 %)
Total number of binary PPIs (saturation %)59 (12.69 %)
The number (and %) of affected PPIs31 (52.54 %)
PPI diameter2
PPI radius1
The average degree of PPI3.032
Assortativity coefficient-0.4565
The network average Clustering coefficient0.479
The number (and %) of a zero Clustering coefficients12 (38.71 %)
The number (and %) of a zero Betweenness Centrality23 (74.19 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acadvl
user protein310.039811.333Acyl-CoA_dh_N (PF02771): Acyl-CoA dehydrogenase, N-terminal domain
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_2 (PF08028): Acyl-CoA dehydrogenase, C-terminal domain
Apc
oncogene, tumor suppressor200APC_N_CC (PF16689): Coiled-coil N-terminus of APC, dimerisation domain
SAS4 (PF15460): Something about silencing, SAS, complex subunit 4
Suppressor_APC (PF11414): Adenomatous polyposis coli tumour suppressor protein
DUF972 (PF06156): Protein of unknown function (DUF972)
Arm (PF00514): Armadillo/beta-catenin-like repeat
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_15aa (PF05972): APC 15 residue motif
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_r (PF05923): APC repeat
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
SAMP (PF05924): SAMP Motif
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_basic (PF05956): APC basic domain
EB1_binding (PF05937): EB-1 Binding Domain
Atf2
oncogene200zf-C2H2 (PF00096): Zinc finger, C2H2 type
bZIP_1 (PF00170): bZIP transcription factor
Atp5l
interactor21.0000ATP-synt_G (PF04718): Mitochondrial ATP synthase g subunit
Ccdc8
interactor31.0000PNMA (PF14893): PNMA
Cdh1
oncogene, tumor suppressor100Cadherin (PF00028): Cadherin domain
Cadherin_C (PF01049): Cadherin cytoplasmic region
Ckap5
interactor40.6670.667PAS_6 (PF08348): YheO-like PAS domain
CLASP_N (PF12348): CLASP N terminal
Spo0A_C (PF08769): Sporulation initiation factor Spo0A C terminal
HEAT (PF02985): HEAT repeat
Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region
DUF1690 (PF07956): Protein of Unknown function (DUF1690)
Clasrp
interactor100DRY_EERY (PF09750): Alternative splicing regulator
S-antigen (PF05756): S-antigen protein
DUF4554 (PF15091): Domain of unknown function (DUF4554)
Transformer (PF06495): Fruit fly transformer protein
DUF4614 (PF15391): Domain of unknown function (DUF4614)
Corona_nucleoca (PF00937): Coronavirus nucleocapsid protein
RAP1 (PF07218): Rhoptry-associated protein 1 (RAP-1)
LRRFIP (PF09738): LRRFIP family
Coq9
interactor31.0000COQ9 (PF08511): COQ9
Dcun1d5
interactor100Cullin_binding (PF03556): Cullin binding
Ecsit
interactor31.0000ECSIT (PF06239): Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C (PF14784): C-terminal domain of the ECSIT protein
Eef2k
interactor100Alpha_kinase (PF02816): Alpha-kinase family
Sel1 (PF08238): Sel1 repeat
DUF1771 (PF08590): Domain of unknown function (DUF1771)
Fam60a
interactor100FAM60A (PF15396): Protein Family FAM60A
Gphn
oncogene31.0000MoCF_biosynth (PF00994): Probable molybdopterin binding domain
Mito_fiss_reg (PF05308): Mitochondrial fission regulator
Tubulin-binding (PF00418): Tau and MAP protein, tubulin-binding repeat
MoeA_N (PF03453): MoeA N-terminal region (domain I and II)
MoeA_C (PF03454): MoeA C-terminal region (domain IV)
Hibch
interactor30.6671.000ECH_2 (PF16113): Enoyl-CoA hydratase/isomerase
Hmgcl
interactor100HMGL-like (PF00682): HMGL-like
Ints9
interactor100Lactamase_B_6 (PF16661): Metallo-beta-lactamase superfamily domain
Beta-Casp (PF10996): Beta-Casp domain
Kif2a
interactor31.0000AAA_23 (PF13476): AAA domain
Kinesin (PF00225): Kinesin motor domain
CREPT (PF16566): Cell-cycle alteration and expression-elevated protein in tumour
LOC103736921
interactor30.6670.667p450 (PF00067): Cytochrome P450
Mcm2
oncogene60.5004.667MCM2_N (PF12619): Mini-chromosome maintenance protein 2
MCM_N (PF14551): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
AAA_3 (PF07726): ATPase family associated with various cellular activities (AAA)
MCM (PF00493): MCM2/3/5 family
Mrm1
interactor21.0000SpoU_sub_bind (PF08032): RNA 2'-O ribose methyltransferase substrate binding
SpoU_methylase (PF00588): SpoU rRNA Methylase family
Mrpl58
interactor40.5003.000RF-1 (PF00472): RF-1 domain
Ndufa13
interactor50.4006.000GRIM-19 (PF06212): GRIM-19 protein
Ndufa4
interactor31.0000B12D (PF06522): NADH-ubiquinone reductase complex 1 MLRQ subunit
Nppa
interactor100ANP (PF00212): Atrial natriuretic peptide
Ntrk1
oncogene70.4008.667LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Oxld1
interactor21.0000Oxidored-like (PF09791): Oxidoreductase-like protein, N-terminal
TAL_effector (PF03377): TAL effector repeat
Ppa2
interactor21.0000Pyrophosphatase (PF00719): Inorganic pyrophosphatase
Rpsa
interactor31.0000Ribosomal_S2 (PF00318): Ribosomal protein S2
40S_SA_C (PF16122): 40S ribosomal protein SA C-terminus
Socs3
tumor suppressor100SH2 (PF00017): SH2 domain
SOCS_box (PF07525): SOCS box
Surf1
interactor100SURF1 (PF02104): SURF1 family

B a c k    t o    T o p ⇑