Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acad8 (from a repository: Thu May 10 22:04:07 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)19
The number (and %) of the onco-proteins3 (15.79 %)
The number (and %) of the tumor suppressors1 (5.26 %)
Total number of binary PPIs (saturation %)24 (14.04 %)
The number (and %) of affected PPIs18 (75.00 %)
PPI diameter2
PPI radius1
The average degree of PPI1.895
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients19 (100.00 %)
The number (and %) of a zero Betweenness Centrality18 (94.74 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acad8
user protein180306.000Acyl-CoA_dh_N (PF02771): Acyl-CoA dehydrogenase, N-terminal domain
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
Acadsb
interactor100Acyl-CoA_dh_N (PF02771): Acyl-CoA dehydrogenase, N-terminal domain
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
Ckap5
interactor200PAS_6 (PF08348): YheO-like PAS domain
CLASP_N (PF12348): CLASP N terminal
Spo0A_C (PF08769): Sporulation initiation factor Spo0A C terminal
HEAT (PF02985): HEAT repeat
Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region
DUF1690 (PF07956): Protein of Unknown function (DUF1690)
Dlg3
interactor100MAGUK_N_PEST (PF10608): Polyubiquitination (PEST) N-terminal domain of MAGUK
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
PDZ_assoc (PF10600): PDZ-associated domain of NMDA receptors
SH3_1 (PF00018): SH3 domain
Guanylate_kin (PF00625): Guanylate kinase
Dusp14
interactor100DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Fam161b
interactor100PTPRCAP (PF15713): Protein tyrosine phosphatase receptor type C-associated
UPF0564 (PF10595): Uncharacterised protein family UPF0564
FUSC-like (PF12805): FUSC-like inner membrane protein yccS
Ipo8
interactor100IBN_N (PF03810): Importin-beta N-terminal domain
Xpo1 (PF08389): Exportin 1-like protein
Cse1 (PF08506): Cse1
RTP1_C1 (PF10363): Required for nuclear transport of RNA pol II C-terminus 1
MSP7_C (PF12948): MSP7-like protein C-terminal domain
HAND (PF09110): HAND
Ldhd
interactor100FAD_binding_4 (PF01565): FAD binding domain
FAD-oxidase_C (PF02913): FAD linked oxidases, C-terminal domain
Mtmr14
interactor200Y_phosphatase3 (PF13350): Tyrosine phosphatase family
Myotub-related (PF06602): Myotubularin-like phosphatase domain
Polm
interactor100BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
HHH_8 (PF14716): Helix-hairpin-helix domain
DNA_pol_lambd_f (PF10391): Fingers domain of DNA polymerase lambda
DNA_pol_B_palm (PF14792): DNA polymerase beta palm
DNA_pol_B_thumb (PF14791): DNA polymerase beta thumb
Ppp1cc
oncogene100STPPase_N (PF16891): Serine-threonine protein phosphatase N-terminal domain
Metallophos (PF00149): Calcineurin-like phosphoesterase
Ptpn14
oncogene200FERM_N (PF09379): FERM N-terminal domain
FERM_M (PF00373): FERM central domain
FERM_C (PF09380): FERM C-terminal PH-like domain
Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Ptpn21
oncogene200FERM_N (PF09379): FERM N-terminal domain
FERM_M (PF00373): FERM central domain
FERM_C (PF09380): FERM C-terminal PH-like domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Ptpn22
interactor100Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Srgap3
oncogene, tumor suppressor100DUF16 (PF01519): Protein of unknown function DUF16
FCH (PF00611): Fes/CIP4, and EFC/F-BAR homology domain
CENP-H (PF05837): Centromere protein H (CENP-H)
TMPIT (PF07851): TMPIT-like protein
DUF4164 (PF13747): Domain of unknown function (DUF4164)
FlaC_arch (PF05377): Flagella accessory protein C (FlaC)
RhoGAP (PF00620): RhoGAP domain
SH3_2 (PF07653): Variant SH3 domain
Med9 (PF07544): RNA polymerase II transcription mediator complex subunit 9
Tns2
interactor200C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
PTEN_C2 (PF10409): C2 domain of PTEN tumour-suppressor protein
cEGF (PF12662): Complement Clr-like EGF-like
SH2 (PF00017): SH2 domain
PTB (PF08416): Phosphotyrosine-binding domain
Trub2
interactor200TruB_N (PF01509): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198): tRNA pseudouridylate synthase B C-terminal domain
Vps37d
interactor100Mod_r (PF07200): Modifier of rudimentary (Mod(r)) protein
Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
Vstm2a
interactor100V-set (PF07686): Immunoglobulin V-set domain
WW_FCH_linker (PF16623): Unstructured linker region between on GAS7 protein
Ig_3 (PF13927): Immunoglobulin domain

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