Find Protein-Protein Interactions (PPI) Network

Choose & Enter
Choose animal: Visualization driver:
Protein/NCBI_ID(s):
Refseq_ID(s):
KEGG_KO(s):


Level of PPIs:
or Upload text file:
Update repository

Visible interactions: Visible interactors: Size of node:

Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acad11 (from a repository: Sat Apr 21 06:26:26 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)43
The number (and %) of the onco-proteins4 (9.30 %)
The number (and %) of the tumor suppressors5 (11.63 %)
Total number of binary PPIs (saturation %)71 (7.86 %)
The number (and %) of affected PPIs42 (59.15 %)
PPI diameter2
PPI radius1
The average degree of PPI2.884
Assortativity coefficient-0.6535
The network average Clustering coefficient0.427
The number (and %) of a zero Clustering coefficients21 (48.84 %)
The number (and %) of a zero Betweenness Centrality36 (83.72 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acad11
user protein420.0231619.000APH (PF01636): Phosphotransferase enzyme family
CUT (PF02376): CUT domain
Acyl-CoA_dh_N (PF02771): Acyl-CoA dehydrogenase, N-terminal domain
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
Amot
oncogene50.5003.000FAP (PF07174): Fibronectin-attachment protein (FAP)
Angiomotin_C (PF12240): Angiomotin C terminal
Gastrin (PF00918): Gastrin/cholecystokinin family
NPV_P10 (PF05531): Nucleopolyhedrovirus P10 protein
TFIIA (PF03153): Transcription factor IIA, alpha/beta subunit
App
interactor130.16755.000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Asap3
interactor100BAR_3 (PF16746): BAR domain of APPL family
Snapin_Pallidin (PF14712): Snapin/Pallidin
PH (PF00169): PH domain
ArfGap (PF01412): Putative GTPase activating protein for Arf
Ank_2 (PF12796): Ankyrin repeats (3 copies)
Bmt2
interactor100RdRP_1 (PF00680): RNA dependent RNA polymerase
Bmt2 (PF11968): 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2
Cd2bp2
interactor100GYF (PF02213): GYF domain
Cdh5
tumor suppressor100Cadherin (PF00028): Cadherin domain
Cadherin_C (PF01049): Cadherin cytoplasmic region
Cntn5
interactor100Ig_3 (PF13927): Immunoglobulin domain
V-set (PF07686): Immunoglobulin V-set domain
I-set (PF07679): Immunoglobulin I-set domain
fn3 (PF00041): Fibronectin type III domain
Dcaf8
interactor100DUF1510 (PF07423): Protein of unknown function (DUF1510)
WD40 (PF00400): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
DUF1635 (PF07795): Protein of unknown function (DUF1635)
Dusp19
interactor31.0000DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Gpbp1l1
interactor100Vasculin (PF15337): Vascular protein family Vasculin-like 1
Gpr156
interactor1007tm_3 (PF00003): 7 transmembrane sweet-taste receptor of 3 GCPR
NYD-SP28 (PF14772): Sperm tail
Gtse1
interactor30.6671.000DUF4680 (PF15730): Domain of unknown function (DUF4680)
GTSE1_N (PF15259): G-2 and S-phase expressed 1
Hspb8
heat shock100HSP20 (PF00011): Hsp20/alpha crystallin family
Il17ra
interactor21.0000IL17R_fnIII_D1 (PF16556): Interleukin-17 receptor, fibronectin-III-like domain 1
IL17R_fnIII_D2 (PF16578): Interleukin 17 receptor D
ECSCR (PF15820): Endothelial cell-specific chemotaxis regulator
SEFIR (PF08357): SEFIR domain
Kctd17
interactor200BTB_2 (PF02214): BTB/POZ domain
Rrn6 (PF10214): RNA polymerase I-specific transcription-initiation factor
SMN (PF06003): Survival motor neuron protein (SMN)
PBP_N (PF17093): Penicillin-binding protein N-terminus
Khdrbs2
interactor100Sam68-YY (PF16568): Tyrosine-rich domain of Sam68
Lzts2
tumor suppressor21.0000CAP_N (PF01213): Adenylate cyclase associated (CAP) N terminal
DUF4250 (PF14056): Domain of unknown function (DUF4250)
ATG16 (PF08614): Autophagy protein 16 (ATG16)
DUF3287 (PF11690): Protein of unknown function (DUF3287)
CENP-F_leu_zip (PF10473): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Fez1 (PF06818): Fez1
DUF1127 (PF06568): Domain of unknown function (DUF1127)
Mier2
interactor100ELM2 (PF01448): ELM2 domain
Myb_DNA-binding (PF00249): Myb-like DNA-binding domain
Mtmr4
interactor200Myotub-related (PF06602): Myotubularin-like phosphatase domain
EspF (PF04806): EspF protein repeat
FYVE (PF01363): FYVE zinc finger
Nr4a1
tumor suppressor100SR-25 (PF10500): Nuclear RNA-splicing-associated protein
zf-C4 (PF00105): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104): Ligand-binding domain of nuclear hormone receptor
Nsfl1c
interactor21.0000UBA_4 (PF14555): UBA-like domain
SEP (PF08059): SEP domain
UBX (PF00789): UBX domain
Pdyn
interactor21.0000Opiods_neuropep (PF01160): Vertebrate endogenous opioids neuropeptide
Pex5
interactor100SHNi-TPR (PF10516): SHNi-TPR
Secretin_N_2 (PF07655): Secretin N-terminal domain
PRY (PF13765): SPRY-associated domain
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_1 (PF00515): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
Pimreg
interactor21.0000DUF1466 (PF07326): Protein of unknown function (DUF1466)
Polr3e
interactor100Sin_N (PF04801): Sin-like protein conserved region
Mit_ribos_Mrp51 (PF11709): Mitochondrial ribosomal protein subunit
Ppp6r1
interactor31.0000SAPS (PF04499): SIT4 phosphatase-associated protein
YihI (PF04220): Der GTPase activator (YihI)
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
Nop25 (PF09805): Nucleolar protein 12 (25kDa)
Spt5_N (PF11942): Spt5 transcription elongation factor, acidic N-terminal
Ppp6r2
interactor40.6672.000SAMP (PF05924): SAMP Motif
SAPS (PF04499): SIT4 phosphatase-associated protein
IMUP (PF15761): Immortalisation up-regulated protein
Ppp6r3
interactor31.0000SAPS (PF04499): SIT4 phosphatase-associated protein
Ptpn14
oncogene31.0000FERM_N (PF09379): FERM N-terminal domain
FERM_M (PF00373): FERM central domain
FERM_C (PF09380): FERM C-terminal PH-like domain
Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Ptpn7
oncogene31.0000Y_phosphatase (PF00102): Protein-tyrosine phosphatase
Sart3
interactor31.0000Vfa1 (PF08432): AAA-ATPase Vps4-associated protein 1
DUF1866 (PF08952): Domain of unknown function (DUF1866)
Suf (PF05843): Suppressor of forked protein (Suf)
DUF3987 (PF13148): Protein of unknown function (DUF3987)
DUF1993 (PF09351): Domain of unknown function (DUF1993)
RR_TM4-6 (PF06459): Ryanodine Receptor TM 4-6
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
LSM_int_assoc (PF16605): LSM-interacting associated unstructured
Lsm_interact (PF05391): Lsm interaction motif
Sdhb
oncogene, tumor suppressor100Fer2_3 (PF13085): 2Fe-2S iron-sulfur cluster binding domain
Fer4_8 (PF13183): 4Fe-4S dicluster domain
Fer4_17 (PF13534): 4Fe-4S dicluster domain
Stk25
interactor21.0000Pkinase (PF00069): Protein kinase domain
DUF1241 (PF06840): Protein of unknown function (DUF1241)
Tbkbp1
interactor200bZIP_2 (PF07716): Basic region leucine zipper
Cep57_CLD_2 (PF14197): Centrosome localisation domain of PPC89
Mod_r (PF07200): Modifier of rudimentary (Mod(r)) protein
APG6 (PF04111): Autophagy protein Apg6
TBD (PF12845): TBD domain
Tcl1b
oncogene21.0000TCL1_MTCP1 (PF01840): TCL1/MTCP1 family
Tinag
interactor100Somatomedin_B (PF01033): Somatomedin B domain
Pacifastin_I (PF05375): Pacifastin inhibitor (LCMII)
Propeptide_C1 (PF08127): Peptidase family C1 propeptide
Peptidase_C1 (PF00112): Papain family cysteine protease
Tmod4
interactor30.6671.000Tropomodulin (PF03250): Tropomodulin
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
LRR_6 (PF13516): Leucine Rich repeat
Trafd1
interactor100zf-Di19 (PF05605): Drought induced 19 protein (Di19), zinc-binding
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DM (PF00751): DM DNA binding domain
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
Trak2
interactor100HAP1_N (PF04849): HAP1 N-terminal conserved region
Spc29 (PF17082): Spindle Pole Component 29
Milton (PF12448): Kinesin associated protein
Ttc4
tumor suppressor21.0000TPR_1 (PF00515): Tetratricopeptide repeat
TPR_2 (PF07719): Tetratricopeptide repeat
Ubxn7
interactor30.6671.000UBA_4 (PF14555): UBA-like domain
Thioredoxin_7 (PF13899): Thioredoxin-like
UIM (PF02809): Ubiquitin interaction motif
Spt5_N (PF11942): Spt5 transcription elongation factor, acidic N-terminal
UBX (PF00789): UBX domain
Zmym5
interactor21.0000zf-FCS (PF06467): MYM-type Zinc finger with FCS sequence motif
zinc_ribbon_2 (PF13240): zinc-ribbon domain

B a c k    t o    T o p ⇑