Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Acad10 (from a repository: Wed Apr 11 13:28:51 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins4 (19.05 %)
The number (and %) of the tumor suppressors2 (9.52 %)
Total number of binary PPIs (saturation %)26 (12.38 %)
The number (and %) of affected PPIs20 (76.92 %)
PPI diameter2
PPI radius1
The average degree of PPI2.286
Assortativity coefficient-0.6168
The network average Clustering coefficient0.263
The number (and %) of a zero Clustering coefficients14 (66.67 %)
The number (and %) of a zero Betweenness Centrality19 (90.48 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Acad10
user protein200.021369.000HAD_2 (PF13419): Haloacid dehalogenase-like hydrolase
APH (PF01636): Phosphotransferase enzyme family
Acyl-CoA_dh_N (PF02771): Acyl-CoA dehydrogenase, N-terminal domain
Acyl-CoA_dh_M (PF02770): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_1 (PF00441): Acyl-CoA dehydrogenase, C-terminal domain
Aifm1
oncogene100AIF-MLS (PF14962): Mitochondria Localisation Sequence
Pyr_redox_2 (PF07992): Pyridine nucleotide-disulphide oxidoreductase
AIF_C (PF14721): Apoptosis-inducing factor, mitochondrion-associated, C-term
UPF0693 (PF16088): UPF0693 family
Aplnr
oncogene1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
App
interactor50.5003.000APP_N (PF02177): Amyloid A4 N-terminal heparin-binding
APP_Cu_bd (PF12924): Copper-binding of amyloid precursor, CuBD
SDA1 (PF05285): SDA1
YtxH (PF12732): YtxH-like protein
Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_E2 (PF12925): E2 domain of amyloid precursor protein
Beta-APP (PF03494): Beta-amyloid peptide (beta-APP)
APP_amyloid (PF10515): beta-amyloid precursor protein C-terminus
Bpnt1
interactor100Inositol_P (PF00459): Inositol monophosphatase family
Bsg
interactor21.0000Ig_2 (PF13895): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_5 (PF16681): Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
Etnk1
interactor100Choline_kinase (PF01633): Choline/ethanolamine kinase
Flna
tumor suppressor21.0000CH (PF00307): Calponin homology (CH) domain
Filamin (PF00630): Filamin/ABP280 repeat
Gars
interactor100WHEP-TRS (PF00458): WHEP-TRS domain
tRNA-synt_2b (PF00587): tRNA synthetase class II core domain (G, H, P, S and T)
HGTP_anticodon (PF03129): Anticodon binding domain
LOC103736087
interactor31.0000Cadherin_2 (PF08266): Cadherin-like
Cadherin_3 (PF16184): Cadherin-like
Cadherin (PF00028): Cadherin domain
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
Mas1
oncogene1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
7TM_GPCR_Srbc (PF10316): Serpentine type 7TM GPCR chemoreceptor Srbc
Ndufa10
interactor100dNK (PF01712): Deoxynucleoside kinase
Npy2r
interactor1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Ntrk3
oncogene, tumor suppressor21.0000LRRNT (PF01462): Leucine rich repeat N-terminal domain
LRR_8 (PF13855): Leucine rich repeat
LRR_1 (PF00560): Leucine Rich Repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
ig (PF00047): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
P2ry8
oncogene1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Pls1
interactor100EF-hand_5 (PF13202): EF hand
EF-hand_7 (PF13499): EF-hand domain pair
GlutR_dimer (PF00745): Glutamyl-tRNAGlu reductase, dimerisation domain
CH (PF00307): Calponin homology (CH) domain
Pth1r
interactor100HRM (PF02793): Hormone receptor domain
7tm_2 (PF00002): 7 transmembrane receptor (Secretin family)
Slc2a12
interactor100Sugar_tr (PF00083): Sugar (and other) transporter
DUF3325 (PF11804): Protein of unknown function (DUF3325)
Tiprl
interactor21.0000TIP41 (PF04176): TIP41-like family
Tmem108
interactor100TMEM108 (PF15759): TMEM108 family
Ybey
interactor100UPF0054 (PF02130): Uncharacterized protein family UPF0054

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