Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abtb2 (from a repository: Thu Apr 12 05:36:53 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins1 (10.00 %)
The number (and %) of the tumor suppressors2 (20.00 %)
Total number of binary PPIs (saturation %)21 (46.67 %)
The number (and %) of affected PPIs9 (42.86 %)
PPI diameter2
PPI radius1
The average degree of PPI3.200
Assortativity coefficient-0.4262
The network average Clustering coefficient0.489
The number (and %) of a zero Clustering coefficients4 (40.00 %)
The number (and %) of a zero Betweenness Centrality8 (80.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abtb2
user protein, oncogene90.19455.000Ank_2 (PF12796): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Cops5
interactor51.0000JAB (PF01398): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
Cul3
interactor60.7003.000Cullin (PF00888): Cullin family
WAC_Acf1_DNA_bd (PF10537): ATP-utilising chromatin assembly and remodelling N-terminal
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Dntt
interactor21.0000BRCT (PF00533): BRCA1 C Terminus (BRCT) domain
HHH_8 (PF14716): Helix-hairpin-helix domain
DNA_pol_lambd_f (PF10391): Fingers domain of DNA polymerase lambda
DNA_pol_B_palm (PF14792): DNA polymerase beta palm
DNA_pol_B_thumb (PF14791): DNA polymerase beta thumb
Dusp26
tumor suppressor200DSPc (PF00782): Dual specificity phosphatase, catalytic domain
Eef1a1
oncogene, tumor suppressor51.0000GTP_EFTU (PF00009): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143): Elongation factor Tu C-terminal domain
Hs1bp3
interactor100PX (PF00787): PX domain
Rbx1
oncogene51.0000zf-rbx1 (PF12678): RING-H2 zinc finger domain
Tctex1d2
interactor100Tctex-1 (PF03645): Tctex-1 family
Xpo1
interactor100IBN_N (PF03810): Importin-beta N-terminal domain
Xpo1 (PF08389): Exportin 1-like protein
Vac14_Fab1_bd (PF12755): Vacuolar 14 Fab1-binding region
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
CRM1_C (PF08767): CRM1 C terminal

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