Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abtb1 (from a repository: Thu Apr 12 06:59:08 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins2 (20.00 %)
The number (and %) of the tumor suppressors1 (10.00 %)
Total number of binary PPIs (saturation %)22 (48.89 %)
The number (and %) of affected PPIs9 (40.91 %)
PPI diameter2
PPI radius1
The average degree of PPI3.400
Assortativity coefficient-0.4079
The network average Clustering coefficient0.659
The number (and %) of a zero Clustering coefficients2 (20.00 %)
The number (and %) of a zero Betweenness Centrality6 (60.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abtb1
user protein90.22252.333Ank_2 (PF12796): Ankyrin repeats (3 copies)
BTB (PF00651): BTB/POZ domain
BACK (PF07707): BTB And C-terminal Kelch
Cars
oncogene31.0000tRNA-synt_1e (PF01406): tRNA synthetases class I (C) catalytic domain
tRNA-synt_1c (PF00749): tRNA synthetases class I (E and Q), catalytic domain
Cul3
interactor41.0000Cullin (PF00888): Cullin family
WAC_Acf1_DNA_bd (PF10537): ATP-utilising chromatin assembly and remodelling N-terminal
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Dnttip1
interactor200DUF4687 (PF15747): Domain of unknown function (DUF4687)
DUF4385 (PF14328): Domain of unknown function (DUF4385)
Eef1a2
oncogene50.7002.333GTP_EFTU (PF00009): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143): Elongation factor Tu C-terminal domain
Eef1d
interactor50.8330.667Cytochrom_C_2 (PF01322): Cytochrome C'
PGA2 (PF07543): Protein trafficking PGA2
UPF0565 (PF10561): Uncharacterised protein family UPF0565
EF-1_beta_acid (PF10587): Eukaryotic elongation factor 1 beta central acidic region
EF1_GNE (PF00736): EF-1 guanine nucleotide exchange domain
Smad2
oncogene, tumor suppressor31.0000MH1 (PF03165): MH1 domain
MH2 (PF03166): MH2 domain
Smad9
interactor31.0000MH1 (PF03165): MH1 domain
MH2 (PF03166): MH2 domain
Vars
interactor40.8330.667GST_C (PF00043): Glutathione S-transferase, C-terminal domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
tRNA-synt_1 (PF00133): tRNA synthetases class I (I, L, M and V)
Anticodon_1 (PF08264): Anticodon-binding domain of tRNA
Val_tRNA-synt_C (PF10458): Valyl tRNA synthetase tRNA binding arm
Zbtb21
interactor100BTB (PF00651): BTB/POZ domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_2 (PF13465): Zinc-finger double domain
NinG (PF05766): Bacteriophage Lambda NinG protein
zf-C2H2 (PF00096): Zinc finger, C2H2 type
OTT_1508_deam (PF14441): OTT_1508-like deaminase
zf-CHCC (PF10276): Zinc-finger domain
zf-C2H2_jaz (PF12171): Zinc-finger double-stranded RNA-binding
zf-C2H2_11 (PF16622): zinc-finger C2H2-type

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