Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcd1 (from a repository: Fri Apr 13 10:44:54 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)24
The number (and %) of the onco-proteins4 (16.67 %)
The number (and %) of the tumor suppressors1 (4.17 %)
Total number of binary PPIs (saturation %)52 (18.84 %)
The number (and %) of affected PPIs23 (44.23 %)
PPI diameter2
PPI radius1
The average degree of PPI4.000
Assortativity coefficient-0.4729
The network average Clustering coefficient0.500
The number (and %) of a zero Clustering coefficients6 (25.00 %)
The number (and %) of a zero Betweenness Centrality12 (50.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcd1
user protein230.099397.667ABC_membrane_2 (PF06472): ABC transporter transmembrane region 2
ABC_tran (PF00005): ABC transporter
Abcd2
interactor30.6670.500ABC_membrane_2 (PF06472): ABC transporter transmembrane region 2
ABC_tran (PF00005): ABC transporter
RVP (PF00077): Retroviral aspartyl protease
Abcd3
interactor70.42910.167ABC_membrane_2 (PF06472): ABC transporter transmembrane region 2
ABC_tran (PF00005): ABC transporter
Agps
interactor31.0000FAD_binding_4 (PF01565): FAD binding domain
FAD-oxidase_C (PF02913): FAD linked oxidases, C-terminal domain
Aplnr
oncogene1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Atp2b2
interactor100Cation_ATPase_N (PF00690): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122): E1-E2 ATPase
DUF106 (PF01956): Integral membrane protein DUF106
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
Cation_ATPase_C (PF00689): Cation transporting ATPase, C-terminus
ATP_Ca_trans_C (PF12424): Plasma membrane calcium transporter ATPase C terminal
Bsg
interactor21.0000Ig_2 (PF13895): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_5 (PF16681): Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
Elavl1
oncogene60.4004.833RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Itpr3
interactor21.0000Ins145_P3_rec (PF08709): Inositol 1,4,5-trisphosphate/ryanodine receptor
MIR (PF02815): MIR domain
RYDR_ITPR (PF01365): RIH domain
DUF1041 (PF06292): Domain of Unknown Function (DUF1041)
SopA (PF13981): SopA-like central domain
RIH_assoc (PF08454): RyR and IP3R Homology associated
Ion_trans (PF00520): Ion transport protein
Mas1
oncogene1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
7TM_GPCR_Srbc (PF10316): Serpentine type 7TM GPCR chemoreceptor Srbc
Ndufa12
interactor31.0000NDUFA12 (PF05071): NADH ubiquinone oxidoreductase subunit NDUFA12
Ndufb4
interactor40.6671.667NDUF_B4 (PF07225): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
Ntrk1
oncogene100.27824.500LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Pex19
interactor50.5003.833Peptidase_M16_C (PF05193): Peptidase M16 inactive domain
Rod-binding (PF10135): Rod binding protein
Pex19 (PF04614): Pex19 protein family
Pex3
interactor31.0000Peroxin-3 (PF04882): Peroxin-3
Pot1
interactor40.6671.000POT1 (PF02765): Telomeric single stranded DNA binding POT1/CDC13
POT1PC (PF16686): ssDNA-binding domain of telomere protection protein
Zn_Tnp_IS1 (PF03811): InsA N-terminal domain
tRNA_anti-codon (PF01336): OB-fold nucleic acid binding domain
Rab7a
oncogene, tumor suppressor40.5002.167Ras (PF00071): Ras family
Rpsa
interactor30.6671.000Ribosomal_S2 (PF00318): Ribosomal protein S2
40S_SA_C (PF16122): 40S ribosomal protein SA C-terminus
Slc15a1
interactor100MFS_2 (PF13347): MFS/sugar transport protein
PTR2 (PF00854): POT family
AlgF (PF11182): Alginate O-acetyl transferase AlgF
Phage_holin_3_6 (PF07332): Putative Actinobacterial Holin-X, holin superfamily III
DUF3899 (PF13038): Domain of unknown function (DUF3899)
Slc27a2
interactor100AMP-binding (PF00501): AMP-binding enzyme
AMP-binding_C (PF13193): AMP-binding enzyme C-terminal domain
Slc39a12
interactor100MRAP (PF15183): Melanocortin-2 receptor accessory protein family
Zip (PF02535): ZIP Zinc transporter
Terf2
interactor40.6671.000TRF (PF08558): Telomere repeat binding factor (TRF)
TERF2_RBM (PF16772): Telomeric repeat-binding factor 2 Rap1-binding motif
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
Myb_DNA-binding (PF00249): Myb-like DNA-binding domain
Vapa
interactor60.4677.667Motile_Sperm (PF00635): MSP (Major sperm protein) domain
DUF972 (PF06156): Protein of unknown function (DUF972)
UL45 (PF05473): UL45 protein, carbohydrate-binding C-type lectin-like
Vps26b
interactor21.0000Vps26 (PF03643): Vacuolar protein sorting-associated protein 26

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