Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcc4 (from a repository: Sat Apr 28 10:37:34 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)13
The number (and %) of the onco-proteins3 (23.08 %)
The number (and %) of the tumor suppressors2 (15.38 %)
Total number of binary PPIs (saturation %)26 (33.33 %)
The number (and %) of affected PPIs12 (46.15 %)
PPI diameter2
PPI radius1
The average degree of PPI3.385
Assortativity coefficient-0.2996
The network average Clustering coefficient0.671
The number (and %) of a zero Clustering coefficients1 (7.69 %)
The number (and %) of a zero Betweenness Centrality6 (46.15 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcc4
user protein120.15299.000ABC_membrane (PF00664): ABC transporter transmembrane region
Atp2b2
interactor40.5003.000Cation_ATPase_N (PF00690): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122): E1-E2 ATPase
DUF106 (PF01956): Integral membrane protein DUF106
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
Hydrolase_3 (PF08282): haloacid dehalogenase-like hydrolase
Cation_ATPase_C (PF00689): Cation transporting ATPase, C-terminus
ATP_Ca_trans_C (PF12424): Plasma membrane calcium transporter ATPase C terminal
Cftr
tumor suppressor60.4006.000ABC_membrane (PF00664): ABC transporter transmembrane region
AAA_15 (PF13175): AAA ATPase domain
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
CFTR_R (PF14396): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
AAA_21 (PF13304): AAA domain, putative AbiEii toxin, Type IV TA system
AAA_23 (PF13476): AAA domain
Erbin
oncogene40.6671.000LRR_8 (PF13855): Leucine rich repeat
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Lgals3
oncogene40.6671.000Gal-bind_lectin (PF00337): Galactoside-binding lectin
Lgals8
interactor21.0000Gal-bind_lectin (PF00337): Galactoside-binding lectin
Lpar1
oncogene30.6671.0007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Reep5
interactor21.0000Phage_holin_3_6 (PF07332): Putative Actinobacterial Holin-X, holin superfamily III
TB2_DP1_HVA22 (PF03134): TB2/DP1, HVA22 family
Slc4a8
interactor21.0000Mu-transpos_C (PF09299): Mu transposase, C-terminal
Band_3_cyto (PF07565): Band 3 cytoplasmic domain
HCO3_cotransp (PF00955): HCO3- transporter family
Slc9a3r1
oncogene, tumor suppressor40.6671.000PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
EBP50_C (PF09007): EBP50, C-terminal
Slc9a3r2
interactor21.0000PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
GRASP55_65 (PF04495): GRASP55/65 PDZ-like domain
EBP50_C (PF09007): EBP50, C-terminal
Snta1
interactor21.0000PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
PH (PF00169): PH domain
Snx27
interactor100PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
PX (PF00787): PX domain
RA (PF00788): Ras association (RalGDS/AF-6) domain

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