Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcc1 (from a repository: Fri Apr 20 16:34:50 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins2 (18.18 %)
The number (and %) of the tumor suppressors1 (9.09 %)
Total number of binary PPIs (saturation %)24 (43.64 %)
The number (and %) of affected PPIs10 (41.67 %)
PPI diameter2
PPI radius1
The average degree of PPI3.273
Assortativity coefficient-0.5148
The network average Clustering coefficient0.540
The number (and %) of a zero Clustering coefficients3 (27.27 %)
The number (and %) of a zero Betweenness Centrality6 (54.55 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcc1
user protein, oncogene100.17866.667DUF4293 (PF14126): Domain of unknown function (DUF4293)
ABC_membrane (PF00664): ABC transporter transmembrane region
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
Canx
interactor40.8330.667TRAP_alpha (PF03896): Translocon-associated protein (TRAP), alpha subunit
Calreticulin (PF00262): Calreticulin family
DUF1510 (PF07423): Protein of unknown function (DUF1510)
Csnk2a1
oncogene41.0000Pkinase (PF00069): Protein kinase domain
Eef1a1
oncogene, tumor suppressor31.0000GTP_EFTU (PF00009): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143): Elongation factor Tu C-terminal domain
Fkbp8
interactor31.0000FKBP_C (PF00254): FKBP-type peptidyl-prolyl cis-trans isomerase
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_1 (PF00515): Tetratricopeptide repeat
Fis1_TPR_C (PF14853): Fis1 C-terminal tetratricopeptide repeat
Lgals8
interactor100Gal-bind_lectin (PF00337): Galactoside-binding lectin
Ntrk1
oncogene60.6003.667LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Ptges3
interactor40.6671.000CS (PF04969): CS domain
Pkinase_C (PF00433): Protein kinase C terminal domain
Raver1
interactor100RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Tmem17
interactor100Transmemb_17 (PF09799): Predicted membrane protein
DUF3043 (PF11241): Protein of unknown function (DUF3043)
Vcp
interactor50.6672.000CDC48_N (PF02359): Cell division protein 48 (CDC48), N-terminal domain
CDC48_2 (PF02933): Cell division protein 48 (CDC48), domain 2
AAA (PF00004): ATPase family associated with various cellular activities (AAA)
TniB (PF05621): Bacterial TniB protein
Vps4_C (PF09336): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099): Domain of unknown function (DUF3944)

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