Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcb8 (from a repository: Sun Apr 15 21:22:54 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins4 (22.22 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)20 (13.07 %)
The number (and %) of affected PPIs17 (85.00 %)
PPI diameter2
PPI radius1
The average degree of PPI2.000
Assortativity coefficient-0.5423
The network average Clustering coefficient0.112
The number (and %) of a zero Clustering coefficients15 (83.33 %)
The number (and %) of a zero Betweenness Centrality17 (94.44 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcb8
user protein, oncogene170.007270.000ABC_membrane (PF00664): ABC transporter transmembrane region
ABC_tran (PF00005): ABC transporter
SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit
AAA_25 (PF13481): AAA domain
Dus (PF01207): Dihydrouridine synthase (Dus)
Fmnl1
interactor100FAP (PF07174): Fibronectin-attachment protein (FAP)
Drf_GBD (PF06371): Diaphanous GTPase-binding Domain
Drf_FH3 (PF06367): Diaphanous FH3 Domain
ABC_tran_CTD (PF16326): ABC transporter C-terminal domain
FH2 (PF02181): Formin Homology 2 Domain
Phage_GPO (PF05929): Phage capsid scaffolding protein (GPO) serine peptidase
DUF4407 (PF14362): Domain of unknown function (DUF4407)
Gabre
interactor100Neur_chan_LBD (PF02931): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
Gpr37
interactor1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
LOC103732400
interactor100UL45 (PF05473): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059): Lectin C-type domain
LOC103739303
interactor100Ldh_1_N (PF00056): lactate/malate dehydrogenase, NAD binding domain
Ldh_1_C (PF02866): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Lpar1
oncogene21.00007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Lpar6
interactor100MscS_TM (PF12794): Mechanosensitive ion channel inner membrane domain 1
7tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Mterf3
interactor100Pex14_N (PF04695): Peroxisomal membrane anchor protein (Pex14p) conserved region
mTERF (PF02536): mTERF
Rab11fip5
interactor200C2 (PF00168): C2 domain
Ribosomal_60s (PF00428): 60s Acidic ribosomal protein
RBD-FIP (PF09457): FIP domain
Rasgrp1
oncogene100RasGEF_N (PF00618): RasGEF N-terminal motif
SPARC_Ca_bdg (PF10591): Secreted protein acidic and rich in cysteine Ca binding region
RasGEF (PF00617): RasGEF domain
FlaC_arch (PF05377): Flagella accessory protein C (FlaC)
EF-hand_1 (PF00036): EF hand
C1_1 (PF00130): Phorbol esters/diacylglycerol binding domain (C1 domain)
CENP-F_leu_zip (PF10473): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Sat1
interactor200Acetyltransf_1 (PF00583): Acetyltransferase (GNAT) family
Scn3b
oncogene100V-set (PF07686): Immunoglobulin V-set domain
DUF843 (PF05814): Baculovirus protein of unknown function (DUF843)
Slc15a1
interactor100MFS_2 (PF13347): MFS/sugar transport protein
PTR2 (PF00854): POT family
AlgF (PF11182): Alginate O-acetyl transferase AlgF
Phage_holin_3_6 (PF07332): Putative Actinobacterial Holin-X, holin superfamily III
DUF3899 (PF13038): Domain of unknown function (DUF3899)
Slc2a12
interactor100Sugar_tr (PF00083): Sugar (and other) transporter
DUF3325 (PF11804): Protein of unknown function (DUF3325)
Slc39a9
interactor100Zip (PF02535): ZIP Zinc transporter
Sppl2b
oncogene21.0000PA (PF02225): PA domain
DUF4079 (PF13301): Protein of unknown function (DUF4079)
Peptidase_A22B (PF04258): Signal peptide peptidase
Sts
interactor100Sulfatase (PF00884): Sulfatase
Sulfatase_C (PF14707): C-terminal region of aryl-sulfatase

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