Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcb6 (from a repository: Sat Apr 14 07:47:32 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)19
The number (and %) of the onco-proteins5 (26.32 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)33 (19.30 %)
The number (and %) of affected PPIs18 (54.55 %)
PPI diameter2
PPI radius1
The average degree of PPI2.421
Assortativity coefficient-0.2895
The network average Clustering coefficient0.388
The number (and %) of a zero Clustering coefficients10 (52.63 %)
The number (and %) of a zero Betweenness Centrality16 (84.21 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcb6
user protein180.033294.000MTABC_N (PF16185): Mitochondrial ABC-transporter N-terminal five TM region
ABC_membrane (PF00664): ABC transporter transmembrane region
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
Bmi1
oncogene31.0000zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207): RAWUL domain RING finger- and WD40-associated ubiquitin-like
Ceacam18
interactor31.0000I-set (PF07679): Immunoglobulin I-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_2 (PF13895): Immunoglobulin domain
Dct
interactor200Laminin_EGF (PF00053): Laminin EGF domain
Tyrosinase (PF00264): Common central domain of tyrosinase
PetG (PF02529): Cytochrome B6-F complex subunit 5
Dpep1
interactor200Peptidase_M19 (PF01244): Membrane dipeptidase (Peptidase family M19)
Ergic3
oncogene100ERGIC_N (PF13850): Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
COPIIcoated_ERV (PF07970): Endoplasmic reticulum vesicle transporter
Flot2
interactor21.0000Band_7 (PF01145): SPFH domain / Band 7 family
Flot (PF15975): Flotillin
YjbH (PF06082): Exopolysaccharide biosynthesis protein YbjH
Gnai2
oncogene21.0000G-alpha (PF00503): G-protein alpha subunit
Grpr
oncogene1007tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
LOC103732400
interactor100UL45 (PF05473): UL45 protein, carbohydrate-binding C-type lectin-like
Lectin_C (PF00059): Lectin C-type domain
LOC103736087
interactor200Cadherin_2 (PF08266): Cadherin-like
Cadherin_3 (PF16184): Cadherin-like
Cadherin (PF00028): Cadherin domain
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
LOC103736445
interactor40.6671.000C1-set (PF07654): Immunoglobulin C1-set domain
C1-set_C (PF16196): C1-set C-terminal domain
Mrap2
interactor100MRAP (PF15183): Melanocortin-2 receptor accessory protein family
Pik3r3
interactor100SH2 (PF00017): SH2 domain
PI3K_P85_iSH2 (PF16454): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
Rnf126
interactor200zinc_ribbon_9 (PF14369): zinc-ribbon
zf-RING_2 (PF13639): Ring finger domain
Rad50_zn_hook (PF04423): Rad50 zinc hook motif
zf-RING_UBOX (PF13445): RING-type zinc-finger
Rnf2
interactor40.6671.000zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-C4_Topoisom (PF01396): Topoisomerase DNA binding C4 zinc finger
RAWUL (PF16207): RAWUL domain RING finger- and WD40-associated ubiquitin-like
Tnf
oncogene200TNF (PF00229): TNF(Tumour Necrosis Factor) family
Tollip
interactor31.0000C2 (PF00168): C2 domain
CUE (PF02845): CUE domain
Tomm40
interactor21.0000Porin_3 (PF01459): Eukaryotic porin

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