Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcb10 (from a repository: Fri Apr 13 14:07:43 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)20
The number (and %) of the onco-proteins2 (10.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)29 (15.26 %)
The number (and %) of affected PPIs19 (65.52 %)
PPI diameter2
PPI radius1
The average degree of PPI2.200
Assortativity coefficient-0.4069
The network average Clustering coefficient0.234
The number (and %) of a zero Clustering coefficients14 (70.00 %)
The number (and %) of a zero Betweenness Centrality18 (90.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcb10
user protein, oncogene190.018335.000ABC_membrane (PF00664): ABC transporter transmembrane region
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
Bak1
oncogene200Bcl-2 (PF00452): Apoptosis regulator proteins, Bcl-2 family
Bcl-2_3 (PF15286): Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like
Ceacam18
interactor31.0000I-set (PF07679): Immunoglobulin I-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_2 (PF13895): Immunoglobulin domain
Ecsit
interactor31.0000ECSIT (PF06239): Evolutionarily conserved signalling intermediate in Toll pathway
ECSIT_C (PF14784): C-terminal domain of the ECSIT protein
Elavl1
oncogene200RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Impdh1
interactor100IMPDH (PF00478): IMP dehydrogenase / GMP reductase domain
Kcna5
interactor200BTB_2 (PF02214): BTB/POZ domain
Ion_trans (PF00520): Ion transport protein
Kcnc4
interactor100Potassium_chann (PF11404): Potassium voltage-gated channel
BTB_2 (PF02214): BTB/POZ domain
Ion_trans (PF00520): Ion transport protein
LOC103736445
interactor31.0000C1-set (PF07654): Immunoglobulin C1-set domain
C1-set_C (PF16196): C1-set C-terminal domain
Lamtor2
interactor100Robl_LC7 (PF03259): Roadblock/LC7 domain
Ndufa2
interactor21.0000L51_S25_CI-B8 (PF05047): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Ndufb11
interactor30.6671.000ESSS (PF10183): ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
Nrg1
interactor100I-set (PF07679): Immunoglobulin I-set domain
EGF (PF00008): EGF-like domain
Neuregulin (PF02158): Neuregulin family
Rnf170
interactor200Pkr1 (PF08636): ER protein Pkr1
DpnI (PF06044): Dam-replacing family
zf-C3HC4 (PF00097): Zinc finger, C3HC4 type (RING finger)
zf-RING_UBOX (PF13445): RING-type zinc-finger
zf-LITAF-like (PF10601): LITAF-like zinc ribbon domain
DUF1232 (PF06803): Protein of unknown function (DUF1232)
Slc24a5
interactor100Na_Ca_ex (PF01699): Sodium/calcium exchanger protein
Slc39a12
interactor100MRAP (PF15183): Melanocortin-2 receptor accessory protein family
Zip (PF02535): ZIP Zinc transporter
Syce3
interactor100Synaptonemal_3 (PF15191): Synaptonemal complex central element protein 3
Tctn3
interactor100DUF1619 (PF07773): Protein of unknown function (DUF1619)
Trdn
interactor100Ndc1_Nup (PF09531): Nucleoporin protein Ndc1-Nup
Asp-B-Hydro_N (PF05279): Aspartyl beta-hydroxylase N-terminal region
DUF4614 (PF15391): Domain of unknown function (DUF4614)
Upk1a
interactor100Tetraspannin (PF00335): Tetraspanin family

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