Find Protein-Protein Interactions (PPI) Network

Choose & Enter
Choose animal: Visualization driver:
Protein/NCBI_ID(s):
Refseq_ID(s):
KEGG_KO(s):


Level of PPIs:
or Upload text file:
Update repository

Visible interactions: Visible interactors: Size of node:

Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abcb1 (from a repository: Wed Apr 11 09:58:39 2018)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins5 (35.71 %)
The number (and %) of the tumor suppressors1 (7.14 %)
Total number of binary PPIs (saturation %)24 (26.37 %)
The number (and %) of affected PPIs13 (54.17 %)
PPI diameter2
PPI radius1
The average degree of PPI2.429
Assortativity coefficient-0.7321
The network average Clustering coefficient0.301
The number (and %) of a zero Clustering coefficients8 (57.14 %)
The number (and %) of a zero Betweenness Centrality11 (78.57 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abcb1
user protein, oncogene130.051144.000DUF4710 (PF15828): Domain of unknown function (DUF4710)
ABC_membrane (PF00664): ABC transporter transmembrane region
DNA_pol3_beta (PF00712): DNA polymerase III beta subunit, N-terminal domain
ABC_tran (PF00005): ABC transporter
SMC_N (PF02463): RecF/RecN/SMC N terminal domain
DUF2207 (PF09972): Predicted membrane protein (DUF2207)
Bccip
interactor21.0000CENP-B_dimeris (PF09026): Centromere protein B dimerisation domain
BCIP (PF13862): p21-C-terminal region-binding protein
Cd4
tumor suppressor200ig (PF00047): Immunoglobulin domain
C2-set (PF05790): Immunoglobulin C2-set domain
CD4-extracel (PF09191): CD4, extracellular
Tcell_CD4_C (PF12104): T cell CD4 receptor C terminal region
Cul7
interactor31.0000Cul7 (PF11515): Mouse development and cellular proliferation protein Cullin-7
ANAPC10 (PF03256): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888): Cullin family
Cullin_Nedd8 (PF10557): Cullin protein neddylation domain
Fbxo15
interactor100F-box-like (PF12937): F-box-like
LOC103739764
interactor30.6671.000Helicase_C (PF00271): Helicase conserved C-terminal domain
HA2 (PF04408): Helicase associated domain (HA2)
OB_NTP_bind (PF07717): Oligonucleotide/oligosaccharide-binding (OB)-fold
Lgals3
oncogene200Gal-bind_lectin (PF00337): Galactoside-binding lectin
Lnx1
interactor100PDZ (PF00595): PDZ domain (Also known as DHR or GLGF)
Mapkap1
interactor100SIN1 (PF05422): Stress-activated map kinase interacting protein 1 (SIN1)
CRIM (PF16978): SAPK-interacting protein 1 (Sin1), middle CRIM domain
SIN1_PH (PF16979): SAPK-interacting protein 1 (Sin1), Pleckstrin-homology
Mapre1
oncogene31.0000CH (PF00307): Calponin homology (CH) domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
EB1 (PF03271): EB1-like C-terminal motif
Ntrk1
oncogene50.5003.000LRR_8 (PF13855): Leucine rich repeat
TPKR_C2 (PF16920): Tyrosine-protein kinase receptor C2 Ig-like domain
Ig_3 (PF13927): Immunoglobulin domain
I-set (PF07679): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714): Protein tyrosine kinase
Pim1
oncogene200Pkinase (PF00069): Protein kinase domain
Psmb8
interactor200Proteasome (PF00227): Proteasome subunit
Uba7
oncogene100E1_FCCH (PF16190): Ubiquitin-activating enzyme E1 FCCH domain
E1_4HB (PF16191): Ubiquitin-activating enzyme E1 four-helix bundle
ThiF (PF00899): ThiF family
E1_UFD (PF09358): Ubiquitin fold domain

B a c k    t o    T o p ⇑