Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abca7 (from a repository: Thu Apr 19 03:59:33 2018)
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PPI Properties:

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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)7
The number (and %) of the onco-proteins1 (14.29 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (47.62 %)
The number (and %) of affected PPIs6 (60.00 %)
PPI diameter2
PPI radius1
The average degree of PPI2.286
Assortativity coefficient-0.2182
The network average Clustering coefficient0.400
The number (and %) of a zero Clustering coefficients3 (42.86 %)
The number (and %) of a zero Betweenness Centrality5 (71.43 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abca7
user protein60.13325.000ABC2_membrane_3 (PF12698): ABC-2 family transporter protein
ABC_tran (PF00005): ABC transporter
AAA_21 (PF13304): AAA domain, putative AbiEii toxin, Type IV TA system
DUF4162 (PF13732): Domain of unknown function (DUF4162)
Gabra3
interactor100Neur_chan_LBD (PF02931): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
Hnrnpd
oncogene31.0000CBFNT (PF08143): CBFNT (NUC161) domain
RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
NID (PF07292): Nmi/IFP 35 domain (NID)
Keratin_2_head (PF16208): Keratin type II head
Htr3a
interactor100Neur_chan_LBD (PF02931): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
Llgl2
interactor200ANAPC4_WD40 (PF12894): Anaphase-promoting complex subunit 4 WD40 domain
RAB3GAP2_N (PF14655): Rab3 GTPase-activating protein regulatory subunit N-terminus
LLGL (PF08366): LLGL2
WD40 (PF00400): WD domain, G-beta repeat
Lgl_C (PF08596): Lethal giant larvae(Lgl) like, C-terminal
Sort1
interactor21.0000Sortilin-Vps10 (PF15902): Sortilin, neurotensin receptor 3,
Sortilin_C (PF15901): Sortilin, neurotensin receptor 3, C-terminal
Syncrip
interactor30.6671.000RRM_1 (PF00076): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608): Limkain b1

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