Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abca3 (from a repository: Wed Apr 11 06:20:52 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)20
The number (and %) of the onco-proteins2 (10.00 %)
The number (and %) of the tumor suppressors1 (5.00 %)
Total number of binary PPIs (saturation %)22 (11.58 %)
The number (and %) of affected PPIs19 (86.36 %)
PPI diameter2
PPI radius1
The average degree of PPI2.100
Assortativity coefficient-0.5130
The network average Clustering coefficient0.201
The number (and %) of a zero Clustering coefficients15 (75.00 %)
The number (and %) of a zero Betweenness Centrality19 (95.00 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abca3
user protein, oncogene190.012338.000ABC2_membrane_3 (PF12698): ABC-2 family transporter protein
ABC_tran (PF00005): ABC transporter
AAA_21 (PF13304): AAA domain, putative AbiEii toxin, Type IV TA system
DUF4162 (PF13732): Domain of unknown function (DUF4162)
Asic4
interactor100DUF2967 (PF11179): Protein of unknown function (DUF2967)
ASC (PF00858): Amiloride-sensitive sodium channel
Atp1b3
interactor21.0000Na_K-ATPase (PF00287): Sodium / potassium ATPase beta chain
Cd79b
oncogene100V-set (PF07686): Immunoglobulin V-set domain
Sigma_reg_N (PF13800): Sigma factor regulator N-terminal
ITAM (PF02189): Immunoreceptor tyrosine-based activation motif
Chrnd
interactor100Neur_chan_LBD (PF02931): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
Eva1c
interactor100Gal_Lectin (PF02140): Galactose binding lectin domain
FAM176 (PF14851): FAM176 family
Fam189a2
interactor100CD20 (PF04103): CD20-like family
Gnai1
oncogene21.0000G-alpha (PF00503): G-protein alpha subunit
Htr3a
interactor100Neur_chan_LBD (PF02931): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932): Neurotransmitter-gated ion-channel transmembrane region
Il17rc
interactor100IL17_R_N (PF15037): Interleukin-17 receptor extracellular region
SEFIR (PF08357): SEFIR domain
LOC103752329
interactor100MHC_I (PF00129): Class I Histocompatibility antigen, domains alpha 1 and 2
C1-set (PF07654): Immunoglobulin C1-set domain
Mcoln3
interactor100PKD_channel (PF08016): Polycystin cation channel
Nrg1
interactor100I-set (PF07679): Immunoglobulin I-set domain
EGF (PF00008): EGF-like domain
Neuregulin (PF02158): Neuregulin family
Pcdhb1
interactor200Cadherin_2 (PF08266): Cadherin-like
Cadherin_3 (PF16184): Cadherin-like
Cadherin (PF00028): Cadherin domain
Cornichon (PF03311): Cornichon protein
Cadherin_C_2 (PF16492): Cadherin cytoplasmic C-terminal
Pth1r
interactor21.0000HRM (PF02793): Hormone receptor domain
7tm_2 (PF00002): 7 transmembrane receptor (Secretin family)
Spint2
tumor suppressor100Kunitz_BPTI (PF00014): Kunitz/Bovine pancreatic trypsin inhibitor domain
Tctn2
interactor21.0000DUF1619 (PF07773): Protein of unknown function (DUF1619)
Tmem9b
interactor100Tmemb_9 (PF05434): TMEM9
Tmprss12
interactor100Trypsin (PF00089): Trypsin
Upk1a
interactor100Tetraspannin (PF00335): Tetraspanin family

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