Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Abat (from a repository: Sat Apr 14 10:32:46 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)31
The number (and %) of the onco-proteins3 (9.68 %)
The number (and %) of the tumor suppressors2 (6.45 %)
Total number of binary PPIs (saturation %)92 (19.78 %)
The number (and %) of affected PPIs30 (32.61 %)
PPI diameter2
PPI radius1
The average degree of PPI5.161
Assortativity coefficient-0.4046
The network average Clustering coefficient0.590
The number (and %) of a zero Clustering coefficients4 (12.90 %)
The number (and %) of a zero Betweenness Centrality11 (35.48 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Abat
user protein300.115657.867Aminotran_3 (PF00202): Aminotransferase class-III
Adsl
interactor21.0000HTH_Tnp_Tc5 (PF03221): Tc5 transposase DNA-binding domain
DUF4089 (PF13318): Protein of unknown function (DUF4089)
Lyase_1 (PF00206): Lyase
DUF1331 (PF07048): Protein of unknown function (DUF1331)
ADSL_C (PF10397): Adenylosuccinate lyase C-terminus
Akr1b10
interactor50.4003.567Aldo_ket_red (PF00248): Aldo/keto reductase family
Aldh7a1
interactor21.0000Aldedh (PF00171): Aldehyde dehydrogenase family
Asgr1
interactor100Lectin_N (PF03954): Hepatic lectin, N-terminal domain
Lectin_C (PF00059): Lectin C-type domain
Bag3
oncogene50.6671.667WW (PF00397): WW domain
RNA_pol_Rpc4 (PF05132): RNA polymerase III RPC4
DUF4124 (PF13511): Domain of unknown function (DUF4124)
BAG (PF02179): BAG domain
Rib_recp_KP_reg (PF05104): Ribosome receptor lysine/proline rich region
Cbs
interactor40.6671.000PALP (PF00291): Pyridoxal-phosphate dependent enzyme
CBS (PF00571): CBS domain
DUF1414 (PF07208): Protein of unknown function (DUF1414)
Cfl1
interactor70.5246.400Cofilin_ADF (PF00241): Cofilin/tropomyosin-type actin-binding protein
Cfl2
interactor70.6672.733Cofilin_ADF (PF00241): Cofilin/tropomyosin-type actin-binding protein
Dstn
interactor50.7001.833Cofilin_ADF (PF00241): Cofilin/tropomyosin-type actin-binding protein
Esd
interactor50.6672.000Esterase (PF00756): Putative esterase
Fah
interactor41.0000FAA_hydrolase_N (PF09298): Fumarylacetoacetase N-terminal
FAA_hydrolase (PF01557): Fumarylacetoacetate (FAA) hydrolase family
Fahd1
interactor50.7001.667FAA_hydrolase (PF01557): Fumarylacetoacetate (FAA) hydrolase family
Gda
interactor40.8330.400Amidohydro_1 (PF01979): Amidohydrolase family
Gpi
interactor70.5247.733XPC-binding (PF09280): XPC-binding domain
PGI (PF00342): Phosphoglucose isomerase
Hsd17b14
interactor200adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
LOC103732255
interactor70.4768.167Enolase_N (PF03952): Enolase, N-terminal domain
Enolase_C (PF00113): Enolase, C-terminal TIM barrel domain
LOC103739303
interactor70.6195.233Ldh_1_N (PF00056): lactate/malate dehydrogenase, NAD binding domain
Ldh_1_C (PF02866): lactate/malate dehydrogenase, alpha/beta C-terminal domain
LOC103745565
interactor80.25019.567Cpn10 (PF00166): Chaperonin 10 Kd subunit
Ldha
interactor110.48916.367Ldh_1_N (PF00056): lactate/malate dehydrogenase, NAD binding domain
Ldh_1_C (PF02866): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Lgr4
interactor31.0000LRRNT (PF01462): Leucine rich repeat N-terminal domain
LRR_8 (PF13855): Leucine rich repeat
LRR_4 (PF12799): Leucine Rich repeats (2 copies)
7tm_1 (PF00001): 7 transmembrane receptor (rhodopsin family)
Pdcd6ip
interactor60.7002.000BRO1 (PF03097): BRO1-like domain
ALIX_LYPXL_bnd (PF13949): ALIX V-shaped domain binding to HIV
MSA-2c (PF12238): Merozoite surface antigen 2c
Pdxk
oncogene100Staphylokinase (PF02821): Staphylokinase/Streptokinase family
Phos_pyr_kin (PF08543): Phosphomethylpyrimidine kinase
Pgm1
interactor70.5716.900PGM_PMM_I (PF02878): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408): Phosphoglucomutase/phosphomannomutase, C-terminal domain
Pgm2
interactor30.6670.667PGM_PMM_I (PF02878): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
PGM_PMM_II (PF02879): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PGM_PMM_III (PF02880): Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
PGM_PMM_IV (PF00408): Phosphoglucomutase/phosphomannomutase, C-terminal domain
Prpf8
oncogene31.0000PRO8NT (PF08082): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083): PROCN (NUC071) domain
RRM_4 (PF10598): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596): U6-snRNA interacting domain of PrP8
PRP8_domainIV (PF12134): PRP8 domain IV core
JAB (PF01398): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PROCT (PF08084): PROCT (NUC072) domain
Qdpr
interactor31.0000adh_short (PF00106): short chain dehydrogenase
Rad23b
oncogene, tumor suppressor30.6671.000ubiquitin (PF00240): Ubiquitin family
Shisa (PF13908): Wnt and FGF inhibitory regulator
UBA (PF00627): UBA/TS-N domain
LCE6A (PF15858): Late cornified envelope protein 6A family
XPC-binding (PF09280): XPC-binding domain
FoP_duplication (PF13865): C-terminal duplication domain of Friend of PRMT1
Sec22c
interactor100Longin (PF13774): Regulated-SNARE-like domain
Sod2
tumor suppressor31.0000Sod_Fe_N (PF00081): Iron/manganese superoxide dismutases, alpha-hairpin domain
Sod_Fe_C (PF02777): Iron/manganese superoxide dismutases, C-terminal domain
Sord
interactor110.37823.233ADH_N (PF08240): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107): Zinc-binding dehydrogenase

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