Find Protein-Protein Interactions (PPI) Network

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Visualization interactions

Powered by Cytoscape Web taxid = 1026970 for: protein(s) Aatk (from a repository: Wed Apr 11 17:32:56 2018)
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Statistics and Network structure information

Statistics of PPI Value(s)
The number of interactors (fusion and proteins)15
The number (and %) of the onco-proteins2 (13.33 %)
The number (and %) of the tumor suppressors2 (13.33 %)
Total number of binary PPIs (saturation %)18 (17.14 %)
The number (and %) of affected PPIs14 (77.78 %)
PPI diameter2
PPI radius1
The average degree of PPI2.133
Assortativity coefficient-0.4880
The network average Clustering coefficient0.268
The number (and %) of a zero Clustering coefficients10 (66.67 %)
The number (and %) of a zero Betweenness Centrality14 (93.33 %)

ACTIVE INTERACTORS


List of active interactors

Interactor,
Domain structure
Type Number
of PPI (degree)
Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam ID): description
Aatk
user protein140.022178.000Pkinase_Tyr (PF07714): Protein tyrosine kinase
Actc1
interactor100Actin (PF00022): Actin
Dnaja1
interactor100DnaJ (PF00226): DnaJ domain
DnaJ_C (PF01556): DnaJ C terminal domain
Dnaja3
tumor suppressor100DnaJ (PF00226): DnaJ domain
DnaJ_C (PF01556): DnaJ C terminal domain
Hspb1
heat shock, oncogene200HSP20 (PF00011): Hsp20/alpha crystallin family
P4ha1
interactor100P4Ha_N (PF08336): Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
TPR_2 (PF07719): Tetratricopeptide repeat
2OG-FeII_Oxy_3 (PF13640): 2OG-Fe(II) oxygenase superfamily
Ppp1ca
oncogene, tumor suppressor21.0000STPPase_N (PF16891): Serine-threonine protein phosphatase N-terminal domain
Metallophos (PF00149): Calcineurin-like phosphoesterase
Ppp1cc
oncogene21.0000STPPase_N (PF16891): Serine-threonine protein phosphatase N-terminal domain
Metallophos (PF00149): Calcineurin-like phosphoesterase
Rcn1
interactor100EF-hand_7 (PF13499): EF-hand domain pair
EF-hand_6 (PF13405): EF-hand domain
EF-hand_4 (PF12763): Cytoskeletal-regulatory complex EF hand
Slc25a1
interactor100Mito_carr (PF00153): Mitochondrial carrier protein
Slc25a11
interactor200Mito_carr (PF00153): Mitochondrial carrier protein
Slc25a12
interactor21.0000EF-hand_7 (PF13499): EF-hand domain pair
EF-hand_6 (PF13405): EF-hand domain
EF-hand_1 (PF00036): EF hand
EF-hand_8 (PF13833): EF-hand domain pair
Mito_carr (PF00153): Mitochondrial carrier protein
Slc25a13
interactor21.0000EF-hand_7 (PF13499): EF-hand domain pair
EF-hand_6 (PF13405): EF-hand domain
EF-hand_8 (PF13833): EF-hand domain pair
Mito_carr (PF00153): Mitochondrial carrier protein
Ssr4
interactor100OppC_N (PF12911): N-terminal TM domain of oligopeptide transport permease C
TRAP-delta (PF05404): Translocon-associated protein, delta subunit precursor (TRAP-delta)
Stk39
interactor100Pkinase (PF00069): Protein kinase domain
OSR1_C (PF12202): Oxidative-stress-responsive kinase 1 C terminal

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